Senior Scientist – Bioinformatician (Data Analysis)

Job Overview

Senior Scientist – Bioinformatician (Data Analysis) – full‑time permanent – South Mimms, Hertfordshire. Hybrid working: at least 8 days/month onsite, up to 12 days depending on business needs.

Key Responsibilities

• Lead design, development and delivery of scalable NGS bioinformatics pipelines (Nextflow, Python, R).
• Manage cloud‑based bioinformatics infrastructure (Google Cloud Platform) ensuring reproducibility, governance and MHRA quality systems compliance.
• Perform quality control, statistical analysis and biological interpretation of multi‑modality NGS data in collaboration with cross‑functional teams.
• Mentor junior bioinformaticians, contribute to publications, grant proposals and integrate emerging technologies.

Required Qualifications

• MSc or equivalent in Bioinformatics, Computational Biology or related discipline.
• Extensive experience delivering large‑scale bioinformatics analysis using cloud computing environments.
• Proficiency in Bash, Python, R, Nextflow and containerisation (Docker, Singularity, GitHub).
• Strong project management skills and ability to communicate complex genomic data to diverse audiences.

Preferred Experience

• Hands‑on pipeline development for genomics, transcriptomics, metagenomics, microbiome profiling and single‑cell analysis.
• Experience with cloud platforms (GCP, AWS, Azure) and Unix/Linux environments.
• Previous leadership of analytical components in multi‑stakeholder projects.

Assessment Method

A=Application, T=Test, I=Interview, P=Presentation – assessment will follow Civil Service Success Profiles.

Contact and Application

Closing date: 9 February 2026. Applications open online. For questions, email careers@mhra.gov.uk.