Disease Area Lead - Hepatology, Renal and Cardiovascular diseases London

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting‑edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success.

This is a rare opportunity to shape the future of clinical delivery at scale. As Disease Area Lead covering Hepatology, Renal and Cardiovascular diseases, you will be the single point of accountability for development operations across major assets within the GSK portfolio—driving strategy, people and performance from early phase through phase IV. You will sit at the heart of our R&D engine, partnering with the senior leaders across the organization to help shape the future of development operations.

Key Responsibilities

• Set and own the strategic vision and operational direction for the disease area portfolio, leading a team of clinical operations leaders to deliver on time, on budget and to quality standards.
• Act as the single accountable point for all operational milestones, timelines and quality standards— from candidate commitment through life‑cycle management.
• Lead the Disease Area Matrix Leadership Team through partnering with key stakeholders to shape the vision, resourcing and delivery strategy to support the clinical portfolio from design through regulatory submission/approvals.
• Define and oversee resourcing strategy across the portfolio, including in‑house vs. outsourcing decisions, and provide input into Business Development due diligence and clinical development planning.
• Proactively identify, own and manage portfolio‑level risks, embedding a Quality by Design mindset and driving inspection readiness across all assets.
• Identify, integrate and scale best practices and innovations across the portfolio—continuously raising the bar for clinical delivery excellence.
• Shape a culture of accountability, collaboration and innovation; develop and retain top talent within your team.
• Partner with senior R&D leadership to ensure operational strategy is fully aligned with GSK's broader objectives, including new partnership assets and new indications of marketed products.

Leading with data and an enterprise mindset

• Drive data‑led decision making: leverage portfolio analytics, delivery metrics and external benchmarks to anticipate risk, prioritise investment and demonstrate value to senior stakeholders.
• Champion data quality and integrity across your portfolio—ensuring that operational data is accurate, timely and decision‑ready at all times.
• Apply an enterprise mindset in every decision: weigh the impact on the wider organisation, not just your disease area, and actively contribute to enterprise‑wide capability building and strategy.
• Represent Clinical Operations at senior governance forums with the credibility and commercial acumen to influence beyond your direct sphere of control.
• Bring external intelligence into the organisation—staying current with industry trends, competitive trial landscapes and evolving regulatory expectations to keep GSK ahead.

Basic Qualifications

• Bachelor’s degree in scientific discipline with knowledge and experience in Biopharmaceutical drug development at a senior strategic level within Clinical Operations.
• Significant senior leadership experience in global clinical operations, with a track record of delivering complex, multi‑asset portfolios across Hepatology, Renal and Cardiovascular diseases.
• Demonstrated ability to lead, coach and develop high‑performing teams across matrix organisations.
• Strong analytical capability—comfortable interrogating data, drawing insight and translating it into clear strategic choices.
• Enterprise‑level thinking: able to hold both the detail and the big picture, and to align decisions with organisational priorities beyond your immediate remit.
• Exceptional stakeholder influencing skills; able to build trust and drive alignment across scientific, commercial and governance audiences.
• Experience operating across all clinical phases, including early phase strategy and life‑cycle management.
• Familiarity with outsourcing strategy, vendor governance and budget management at portfolio scale.

Preferred Qualifications

• Advanced qualification preferred.