Medical Assessor (CDF)

We are currently looking for a Medical Assessor to join our Clinical Investigations and Trials Function within the Scientific Research and Innovation group. This is a full-time opportunity, on a permanent basis. The role will be based in 10 South Colonnade, Canary Wharf London, E14 4PU. Government departments and agencies are working towards implementing a minimum 60% attendance in office sites. We are currently implementing a flexible, hybrid way of working, with a minimum of 8 days per month working on site to enable the collaboration and contact with partners and stakeholders needed to deliver MHRA business.

The Medicines and Healthcare products Regulatory Agency enhance and improve the health of millions of people every day through the effective regulation of medicines and medical devices, underpinned by science and research. The Innovation and Compliance Group delivers public health impact, world‑leading research innovation, and a unique proposition via an ambitious Science Strategy which will balance innovation against sustainability and affordability. It is divided into 3 sub‑Groups: Innovation Accelerator and Regulatory Science, Clinical Investigations and Trials, and Standards and Compliance.

The clinical investigations and trials function ensure the efficient, pragmatic, proportionate and patient‑centred advice for, and assessment of, clinical investigations into the performance and safety of medical devices and diagnostics as well as clinical trials of investigational medicinal products.

What’s the role?

The role encompasses a broad range of activities from assessing clinical aspects of clinical trial authorisation (CTA) applications and amendments to existing CTAs, to providing scientific advice to companies around clinical/regulatory issues for the development of new products. The role holder will be expected to contribute to policy and strategy development to maintain and enhance the reputation of the UK as a great place to conduct clinical research, identifying synergies and opportunities for streamlining across the functional areas of the Science, Research and Innovation Group. The role is both intellectually challenging and rewarding and provides significant opportunity for scientific and regulatory learning.

Key Responsibilities

• Carry out the risk‑based assessment of data provided in clinical trial authorisation initial and amendment applications for chemical, biological or advanced therapy products making appropriate recommendations and decisions in line with the protection of public health.
• Prepare and present objective assessment reports or other scientific papers to expert advisory bodies.
• Manage own workload working in conjunction with the support team and other assessors to meet agency deadlines.
• Provide scientific and clinical trial expertise in advice meetings with external stakeholders, obtaining cross‑agency or external support depending on the questions posed.
• Provide a written response to enquiries submitted through a variety of sources, including via internal customer‑facing portals and the wider civil service.
• Contribute where medical input is required in critical clinical trial projects and contribute to the Innovative Licensing and Access Pathway (ILAP).

Who are we looking for?

Our Successful Candidate Will Have

• Substantial proven experience working as a medical assessor in the assessment of Clinical Trial Authorisation (CTA) applications, making independent decisions on their suitability for approval within regulatory timelines, as well as experience providing scientific or regulatory advice.
• Demonstrating a consistently high level of performance in the role including a high throughput of work commensurate with experience and knowledge to meet required deadlines.
• Degree in Medicine, registered with the General Medical Council, with a relevant postgraduate qualification and/or experience.
• Previous experience of the assessment of clinical aspects of a clinical trial authorisation or marketing authorisation application.
• Up to date knowledge of relevant legislation and procedures applicable to the regulation of clinical trials.

Person Specification

Method of assessment: A=Application, T=Test, I=Interview, P=Presentation

Behaviour Criteria

• Communicating and Influencing (A, I)
• Managing a Quality Service (A, I)
• Delivering at Pace (A, I)
• Making Effective Decisions (A, I)

Experience Criteria

• Substantial proven experience working as a medical assessor in the assessment of Clinical Trial Authorisation (CTA) applications, making independent decisions on their suitability for approval within regulatory timelines, as well as experience providing scientific or regulatory advice. Demonstrating a consistently high level of performance in the role including a high throughput of work commensurate with experience and knowledge to meet required deadlines (A, I)

Technical Criteria

• Degree in Medicine, registered with the General Medical Council, with a relevant postgraduate qualification and/or experience (A)
• Previous experience of the assessment of clinical aspects of a clinical trial authorisation or marketing authorisation application (A)
• Up to date knowledge of relevant legislation and procedures applicable to the regulation of clinical trials (I)

If you require any disability related adjustments at any point during the process, please contact careers@mhra.gov.uk as soon as possible.

Additional Information

For Internal Applicants: Eligible applicants should discuss their intention/application and supporting statement with their line manager. Following the discussion, the line manager and countersigning manager must complete the Managers Endorsement Form, which is then submitted by the internal applicant as an attachment document. It is recommended that you allow your line manager at least three working days to complete this to ensure your application can be submitted on time.

The Selection Process

We use the Civil Service Success Profiles to assess our candidates. Online application form, including a statement of suitability, of no more than 1,000 words demonstrating how you meet the person specification. Please ensure all application questions are completed in full; your application may not be considered if any responses are left blank. Our applications are CV blind, and our Hiring Managers will not be able to access your CV when reviewing your application. Please ensure not to include any personal identifying information on your supporting information. Interview, which can include questions based on the Behaviour, Experience, Technical and Strengths Success Profiles.

In the instance that we receive a high number of applications, we will hold an initial sift based on the lead criteria of substantial proven experience working as a medical assessor in the assessment of Clinical Trial Authorisation (CTA) applications, making independent decisions on their suitability for approval within regulatory timelines, as well as experience providing scientific or regulatory advice. Applications are scored based on the statement of suitability provided.

Closing date: 24 August 2026

Shortlisting date: from 25 August 2026

Interview date: w/c 07 September 2026

If you need assistance applying for this role or have any other questions, please contact careers@mhra.gov.uk

Successful candidates must pass a disclosure and barring security check as well as animal rights and pro‑life activism checks. People working with government assets must complete basic personnel security standard checks. Applicants who are successful at interview will be, as part of pre‑employment screening subject to a check on the Internal Fraud Database (IFD). This check will provide information about employees who have been dismissed for fraud or dishonesty offences.