Principal Epidemiologist in City of London

Principal Epidemiologist

Medicines and Healthcare products Regulatory Agency (MHRA) is looking for an experienced Principal Epidemiologist to join our Scientific Data & Insight Function within the Safety and Surveillance group.

This full‑time, 2‑year fixed‑term contract (internal move/loan/secondment or temporary promotion) will be based in 10 South Colonnade, Canary Wharf, London E14 4PU. Attendance is required at least 8 days/month in the office, with flexibility up to 12 days/month as required. The role is open to UK residents only.

Key Responsibilities

• Conduct high‑quality research in the wider fields of pharmacoepidemiology or device epidemiology.
• Publish research papers in high‑quality journals.
• Build and maintain collaborations with UK and international academic, regulatory, and healthcare partners to enhance the MHRA’s epidemiological capabilities.
• Proactively identify and secure external research funding opportunities, preparing high‑quality proposals that expand the Agency’s resources and influence.
• Mentor colleagues, foster innovation, and contribute to building in‑house expertise and capability in pharmacoepidemiology and device epidemiology.

Qualifications

• Doctoral qualification (or equivalent advanced experience) in epidemiology, statistics, or a closely related quantitative discipline.
• Demonstrated leadership in solving complex, strategic challenges, using advanced epidemiological methods.
• A strong track record in high‑quality research as evidenced by a substantial publication record.
• Internationally recognised expertise in at least one of the following domains, with significant influence on practice, policy, or methodological development:
  • Bayesian methods
  • Causal inference
  • Dynamic benefit‑risk assessment
  • Genetic and molecular epidemiology
  • Machine learning and AI
  • Simulation‑based benefit‑risk models
  • Systems epidemiology
  • Similar advanced and novel methods
• Recognised thought leadership, evidenced by publications, invited keynotes, advisory roles, or leadership of expert working groups, both nationally and internationally.
• Proven ability to shape organisational culture and strategic direction, particularly through mentoring, coaching, and fostering innovation.

Selection Process

• Online application form, including questions based on the Behaviour, Experience and Technical Success Profiles.
• Presentation, to be prepared as part of your interview.
• Interview, which can include questions based on the Behaviour, Experience, Technical and Strengths Success Profiles.

Use of AI in Job Applications

Applicants must ensure that anything submitted is factually accurate and truthful. Plagiarism can include presenting the ideas and experience of others, or generated by artificial intelligence, as your own.

Contact

For enquiries or assistance, email careers@mhra.gov.uk.

Closing Date

24 November 2025