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- Tasks: Join a groundbreaking neonatal research trial, recruiting babies for a Phase I study.
- Company: Manchester University NHS Foundation Trust is the largest NHS Trust in England, focused on innovation and collaboration.
- Benefits: Gain research experience, present findings, publish work, and potentially complete a higher degree.
- Why this job: Be part of an impactful study with expert supervision in a supportive environment.
- Qualifications: Must have six months of neonatal experience and hold a full MRCPCH or equivalent.
- Other info: This role is not accredited for training but offers valuable Out-of-Programme experience.
The predicted salary is between 48000 - 72000 £ per year.
Applications are invited for a clinical research fellow (CRF) for 24 months as 0.8 whole time equivalent position at ST4+ onwards to support the local recruitment of babies with moderate-severe hypoxic ischaemic encephalopathy (HIE) to a Phase I neonatal neuroprotection trial.
The ACUMEN Study is an international, multicentre Phase I, non-randomised dose escalation neonatal trial funded by the Medical Research Council (MRC). The Primary objectives are:
- Safety Profile Assessment: to assess the safety profile of melatonin across all dose levels being studied based on the occurrence of dose-limiting events (DLE).
- The attainment of putative therapeutic plasma melatonin levels (in the range of 15-30mg/L) across dose levels being studied.
- The attainment of putative ethanol safety (BAC levels < 0.25g/L) across dose levels being studied.
To identify the recommended Phase 2 dose (RP2D).
Babies with moderate-severe HIE who are eligible for therapeutic hypothermia will be recruited from ten tertiary neonatal units in London (UCLH, Royal London Hospital), Manchester, Edinburgh, Dublin (Coombe and Rotunda Hospitals), Cork, Sheffield, Melbourne (Monash Medical Centre) and Adelaide.
This post is suitable for a paediatric or neonatal trainee, holding an allocated NTN number or equivalent looking to develop research experience and complete a higher degree.
Main duties of the job
Professor Nikki Robertson and Dr Ajit Mahaveer will provide research and clinical supervision to the successful applicant. The CRF position is funded for a period of 24 months. The research time will give the successful applicant an opportunity to pursue research studies related to neonatal neuroprotection and neurocritical care. It is likely that this work at the cutting edge of neonatal research will lead to presentations in national and international meetings and publications in peer reviewed journals. For those who wish, completion of a higher degree could be possible.
Applicants must possess a minimum of six months of previous experience in Neonates at the Tier 2 level, and a full MRCPCH or equivalent level is mandatory. While this post is not accredited for training purposes, it may be appropriate for a trainee seeking Out-of- Programme opportunities for research or experience. The trainee must secure approval for OOP(R)/OOP(E) from their Postgraduate Dean.
About us
MFT is England\’s largest NHS Trust with a turnover of £3bn & is on a different scale than most other NHS Trusts. We\’re creating an exceptional integrated health & social care system for the 1 million patients who rely on our services every year.
Bringing together 10 hospitals & community services from across Manchester, Trafford & beyond, we champion collaborative working & transformation, encouraging our 30,000 workforce to pursue their most ambitious goals. We set standards that other Trusts seek to emulate so you\’ll benefit from a scale of opportunity that is nothing short of extraordinary.
We\’ve also created a digitally enabled organisation to improve clinical quality, patient & staff experience, operational effectiveness & driving research and innovation through the introduction of Hive our brand-new Electronic Patient Record system which we\’ve launched in September 2022.
We\’re proud to be a major academic Research Centre & Education provider, providing you with a robust infrastructure to encourage and facilitate high-quality research programmes. What\’s more, we\’re excited to be embarking on our new Green Plan which will set out how MFT continues to play its part in making healthcare more sustainable.
At MFT, we create and foster a culture of inclusion and belonging, provide equal opportunities for career development that are fair, open and transparent, protecting your health and wellbeing, and shaping the future of our organisation together.
Job description
Job responsibilities
To find out more about the key responsibilities and the specific skills and experience youll need, take a look at the Job Description & Person Specification attachments under the Supporting Documents heading. So that youre even more equipped to make an informed decision to apply to us, youll need to take time to read the Candidate Essentials Guide that sits with the Job Description and Person Specification. This document provides you with details about the Trust, our benefits and outlines how we care for you as you care for others. Most importantly, it also contains critical information youll need to be aware of before you submit an application form.
Diversity Matters
MFT is committed to promoting equality of opportunity, celebrating and valuing diversity, and eliminating any form of unlawful discrimination across our workforce, ensuring our people are truly representative of the communities we serve. All individuals regardless of age, disability, gender reassignment, marriage and civil partnership, pregnancy and maternity, race, religion or belief, sex, and sexual orientation are encouraged to apply for this post. As an inclusive employer, we are here to support you. If you have any special requirements to help you with your application, email our team at resourcing@mft.nhs.uk.
Were looking forward to hearing from you!
Person Specification
Other requirements
Essential
- Full registration (or eligible for full registration) with the General Medical Council and License to Practice
Qualifications
Essential
- Medical Degree
- Qualifications: MRCPCH or MRCOG
- Certificate in Good Clinical Practice
Experience and Knowledge
Essential
- Comprehensive understanding of UK Clinical Trials Regulations, ICH Good Clinical Practice, the European Directives on Clinical Trials and Good Clinical Practice and the Department of Health\’s Research Governance Framework
- Appreciation/knowledge of NHS Plan in related areas
Desirable
- Previous experience of neonatal research
- Publications as first or last author in internationally refereed journals on topics mentioned in Job Description
- Clinical and Research Governance application in clinical service delivery
- Good knowledge of neonatal neurocritical care
Skills and Abilities
Essential
- Ability to work both independently and collaboratively demonstrating good organisation and management skills
- Demonstration of excellent interpersonal, oral and written communication skills
- Ability to present data publicly in poster and platform form
Desirable
- Proven ability to attract grant funding to support research
- Ability to design and implement research studies
- Ability to develop new techniques and projects
- Ability to supervise academic work by undergraduates, masters and doctorate students
Personal attributes
Essential
- Ability to work as part of a multidisciplinary team, and collaborate with clinical researchers and basic scientists
- Commitment to academic research
Any attachments will be accessible after you click to apply.
349-SMH-7269280-RL4
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Senior Locally Employed Doctor in Neonatal Research employer: Manchester University NHS Foundation Trust
Contact Detail:
Manchester University NHS Foundation Trust Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Locally Employed Doctor in Neonatal Research
✨Tip Number 1
Reach out to Professor Nikki Robertson or Dr Ajit Mahaveer for an informal chat about the role. This can give you valuable insights into the expectations and culture of the team, making you a more informed candidate.
✨Tip Number 2
Familiarise yourself with the ACUMEN trial and its objectives. Understanding the specifics of the study will not only help you in interviews but also demonstrate your genuine interest in the research.
✨Tip Number 3
Network with professionals in neonatal research, especially those who have experience with clinical trials. They can provide tips on how to navigate the application process and may even refer you to opportunities.
✨Tip Number 4
Consider attending relevant conferences or workshops related to neonatal research. This will not only enhance your knowledge but also expand your professional network, which could be beneficial when applying for this position.
We think you need these skills to ace Senior Locally Employed Doctor in Neonatal Research
Some tips for your application 🫡
Understand the Role: Familiarise yourself with the specifics of the Senior Locally Employed Doctor in Neonatal Research position. Highlight your relevant experience in neonatal care and research, particularly in relation to hypoxic ischaemic encephalopathy (HIE).
Tailor Your CV: Craft your CV to emphasise your neonatal experience, MRCPCH qualification, and any research projects you've been involved in. Make sure to include specific achievements and skills that align with the job description.
Write a Compelling Cover Letter: In your cover letter, express your enthusiasm for the role and the ACUMEN trial. Discuss how your background makes you a suitable candidate and mention your desire for research experience and potential for a higher degree.
Proofread Your Application: Before submitting, carefully proofread your application materials. Check for spelling and grammatical errors, and ensure that all information is clear and concise. A polished application reflects your attention to detail.
How to prepare for a job interview at Manchester University NHS Foundation Trust
✨Know Your Research
Familiarise yourself with the ACUMEN trial and its objectives. Be prepared to discuss how your experience aligns with the study's goals, particularly regarding neonatal neuroprotection and hypoxic ischaemic encephalopathy.
✨Highlight Relevant Experience
Emphasise your six months of neonatal experience at Tier 2 level. Discuss specific cases or situations where you demonstrated your skills and knowledge in a clinical research setting.
✨Prepare Questions
Have insightful questions ready for your interviewers about the role, the team, and the research environment at Manchester University NHS Foundation Trust. This shows your genuine interest and helps you assess if it's the right fit for you.
✨Showcase Your Collaborative Spirit
Since this role involves working across multiple neonatal units, highlight your ability to work collaboratively in a team. Share examples of how you've successfully collaborated with colleagues in past roles.
