Director, Legal - UK

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

Key Responsibilities:

Strategic Business Partner

• Serve as the primary legal advisor to the UK General Manager and local Leadership Team.
• Provide practical, solution-oriented legal advice to support commercial decision-making and business strategy.
• Participate as a trusted member of the UK leadership team, proactively identifying legal risks and opportunities.
• Support the successful launch and ongoing commercialisation of the Company's oncology portfolio in UK.

Commercial & In-Market Legal Advice

• Advise on all legal aspects of commercial operations within UK.
• Support Sales, Marketing, Medical Affairs, Market Access, Government Affairs, Regulatory Affairs and Finance.
• Provide legal guidance on promotional activities, field-based engagements, digital initiatives, early access and patient support programs.
• Review and negotiate commercial agreements supporting the UK business.

Market Access & Pricing

• Lead legal support for market access and reimbursement initiatives.
• Draft and negotiate rebate agreements, market access agreements and value-based arrangements with statutory and private healthcare stakeholders.
• Advise on pricing, reimbursement, tender participation and healthcare contracting.
• Partner with Market Access and Government Affairs to assess legal implications of evolving reimbursement policies.

Business Partner Relationships

• Support strategic relationships with healthcare institutions, research organisations, commercial partners and service providers.
• Draft and negotiate agreements with consultants, vendors, commercial service providers and other business partners.
• Advise on governance of strategic collaborations and alliance relationships.
• Support third-party due diligence and ongoing relationship management.
• Advise on UK and European competition law issues affecting pharmaceutical commercialisation.
• Counsel business teams on pricing, distribution, information exchanges, collaborations, tenders and interactions with competitors.
• Provide legal guidance regarding healthcare professional engagements, transfers of value, sponsorships, grants and interactions with healthcare organisations.
• Partner closely with Compliance to ensure adherence to applicable pharmaceutical industry codes and internal policies.
• Manage actual and threatened litigation involving the UK affiliate.
• Coordinate with external counsel on commercial disputes, regulatory matters, employment-related legal issues (working alongside Employment Counsel), product-related claims and investigations.
• Develop litigation strategy in collaboration with the VP Legal, Europe and senior management.
• Manage legal holds, investigations and dispute resolution processes.

Regulatory & Local Legal Support

• Advise on UK legal requirements impacting commercial operations.
• Support implementation of new legislation affecting pharmaceutical companies.
• Provide legal guidance on consumer protection, unfair competition, advertising, procurement and commercial regulations.
• Coordinate with specialist external counsel on complex local law matters where appropriate.

Cross-Functional Collaboration

• Partner with Global Legal, Compliance, Regulatory Affairs, Medical Affairs, Quality, Supply Chain, Finance and Human Resources.
• Support internal investigations, audits and compliance initiatives.
• Develop and deliver legal training to the UK affiliate.
• Contribute to the development of legal policies, templates and best practices across the European legal function.

Outside Counsel Management

• Select, instruct and manage UK external counsel.
• Oversee litigation budgets and legal spend.
• Ensure efficient delivery of high-quality legal services while controlling costs.

Qualifications:

Required

• J.D. (or equivalent law degree) and admission to practice in at least one U.S. state or a UK or European jurisdiction.
• 8–12 years of legal experience, including significant in-house or law firm experience supporting the life sciences industry.
• Strong knowledge of UK pharmaceutical law and commercial legal issues.
• Experience advising commercial pharmaceutical organisations.
• Experience supporting market access, reimbursement or healthcare contracting.
• Familiarity with competition law, healthcare compliance and pharmaceutical promotional regulations.
• Demonstrated ability to advise senior business leaders in a highly regulated environment.
• Excellent negotiation, communication and stakeholder management skills.

Preferred

• Experience supporting oncology or specialty pharmaceutical products.
• In-house legal experience supporting a UK pharmaceutical affiliate.
• Experience supporting a first commercial launch.
• Familiarity with UK statutory health insurance (GKV) contracting and reimbursement frameworks.
• Experience managing commercial litigation and regulatory investigations.
• Fluency in English.

Core Competencies

• Strategic business partnership
• Commercial judgment
• Executive presence and influencing skills
• Competition law expertise
• Healthcare regulatory knowledge
• Negotiation and contracting
• Litigation management
• Cross-functional collaboration
• Pragmatic risk management
• Strong project leadership

Travel

Approximately 10–20% travel within UK and internationally, including periodic travel to the Company's U.S. and European headquarters and European offices.

Why Join Us

This is a unique opportunity to serve as the lead legal advisor for one of the Company's most important commercial markets during a transformational period. As the Company launches its first oncology therapy in Europe, you will play a central role in shaping legal strategy, partnering directly with the UK General Manager and executive leadership, and helping build a high-performing commercial organisation that delivers innovative medicines to patients.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, colour, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

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