At a Glance
- Tasks: Lead innovative R&D projects in mammalian cell expression technologies and hands-on lab work.
- Company: Join Lonza, a leader in biopharmaceutical manufacturing in Cambridge.
- Benefits: Agile career growth, inclusive culture, and performance-based compensation.
- Other info: Collaborative environment with opportunities to mentor and develop junior scientists.
- Why this job: Make a real impact on the future of therapeutic protein production.
- Qualifications: PhD or equivalent in a relevant field with strong R&D experience.
The predicted salary is between 45000 - 55000 £ per year.
Lead Scientist – Cell Expression Technologies Location.
Cambridge, UKThe actual location of this job is in Cambridge, UK.
Relocation assistance is available for eligible candidates and their families, if needed.
Join Lonza’s team in Cambridge and help shape the next generation of mammalian cell expression technologies.
As Lead Scientist, you will lead innovative R&D projects developing industrially relevant CHO expression platforms for complex therapeutic proteins, with approximately 80% of your time spent hands-on in the laboratory.
This is a fully site-based role.
Working together in person supports close, real-time collaboration and the technical precision needed to manufacture medicines to the highest quality and safety standards.
What you will get: An agile career and dynamic working culture.
An inclusive and ethical workplace.
Compensation programs that recognize high performance.
A variety of benefits dependent on role and location.
The full list of our global benefits can be found here: .
What you will do: Lead key mammalian cell expression projects, spending approximately 80% of your time performing hands-on laboratory work and driving delivery of project goals.
Develop and contribute to next-generation CHO-based expression hosts for the production of complex therapeutic proteins, including transferring new technologies towards GMP manufacturing.
Engineer mammalian cell lines using approaches including random and targeted integration and CRISPR-based gene editing, and develop expression vectors using state-of-the-art molecular biology and assembly techniques.
Characterise engineered cell lines using a range of analytical approaches, including NGS, dd PCR, q PCR, flow cytometry and advanced cell culture techniques.
Analyse, evaluate and sign off experimental data, maintaining high-quality, traceable records and communicating findings through clear written and oral reports.
Collaborate with cross-functional teams and mentor junior scientists, supporting knowledge sharing, technical development and delivery of expression solutions.
Build world-leading expertise in mammalian expression systems through technology development, idea generation, internal stakeholder engagement and ownership of proof-of-concept projects.
What we are looking for: A Ph D or equivalent advanced scientific qualification, combined with relevant R&D experience in an academic or industrial environment.
Strong practical expertise in CHO cell line engineering and mammalian expression system development.
Hands-on experience in molecular biology, including the development and manipulation of expression systems.
Experience using cell line engineering and characterisation techniques, with the ability to design, execute and interpret complex experiments.
Demonstrated experience leading scientific projects, mentoring colleagues and contributing to technology development and
Cell & Molecular Scientist in Cambridge employer: Lonza
Lonza is an exceptional employer, providing a vibrant work culture in Cambridge where innovation thrives. Employees benefit from a competitive package and ample opportunities for professional growth, all while contributing to groundbreaking advancements in therapies that impact patients worldwide.
