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- Tasks: Join us as an Aptamer Scientist, designing libraries and conducting wet lab experiments.
- Company: Level Zero is a top startup revolutionising health monitoring with cutting-edge biosensor technology.
- Benefits: Enjoy competitive salary, equity options, and opportunities for travel and career growth.
- Why this job: Be part of a mission-driven team making a real impact on personalised health.
- Qualifications: Ph.D. in relevant fields; expertise in SELEX, molecular biology, and data analysis required.
- Other info: Work closely with industry experts in a dynamic startup environment.
The predicted salary is between 36000 - 60000 £ per year.
About Level Zero
Level Zero is pioneering next-generation biosensor technology for precise, real-time monitoring of critical endocrine biomarkers. Recognised as one of the top 20 startups across all categories worldwide at TechCrunch Disrupt 2024—and backed by top-tier organisations like SOSV and Entrepreneur First—we’re pushing the boundaries of biochemistry and nanotechnology to revolutionize personalised health.
Founded by two seasoned engineers, we bring extensive experience in R&D, technical innovation, and commercial strategy to transform the way people monitor their health. Our mission is bold: to revolutionise health management by delivering clinical-grade data directly to individuals, wherever they are.
We’re seeking driven innovators to join us in pushing the boundaries of biosensing and health tech, making personalised health monitoring a reality for everyone. To achieve this ambitious vision, we’re assembling the best team in the world—dedicated to turning cutting-edge science into life-changing, real-world solutions.
About The Role
We are excited to welcome a aptamer scientist to join our team. The ideal candidate will have expertise in SELEX, aptamer library design, and binding analysis using techniques like SPR and BLI. Proficiency in bio-conjugation reactions, nucleic acid structure characterization. Strong data analysis skills with tools like Python or R are required. Experience with electrochemical aptamer-based biosensors is a plus. The candidate will work closely with the nano-biosensor team to advance R&D milestones.
This is a full-time, in-person role primarily based in London.
Some examples of what you might do:
- Design Library for aptamer selection against various small molecule or proteins
- Wet lab experiments to perform selections, identification and binding analysis of candidates using fluorescence, electrochemical based method, or biophysical techniques such as Surface plasmon / Biolayer interferometry
- Perform various bio-conjugation reactions and purifications of oligonucleotides
Analyse and organise raw experimental data as technical reports.
- Work closely with the Nano biosensor team leader for work progress towards R&D milestones
- Attend R&D-related trainings and seminars for continuous updates on the latest trend in small molecule sensing technologies
What You Bring
- A Ph.D. in Molecular Biology, Biochemistry, Nucleic Acid Chemistry, or a related field. Postdoctoral experience (university or industrial) will be a plus for this position
The ideal candidate will possess expertise in the following areas:
- Proficient in Capture-SELEX, including library and primer design, optimisation of regeneration of libraries
- Skilled in molecular biology techniques, including RT-PCR, cloning, in vitro transcription, and various gel electrophoresis (denaturing, native PAGE and agarose)
- In-depth knowledge of fluorescence-based assays, such as fluorescence resonance energy transfer (FRET) and other fluorescence detection methods. Experience with standard gel scanning instruments such TYPHOON or Geldoc etc
- Experience with Nucleic Acid secondary structure characterisation by biophysical and biochemical techniques such as CD Spectroscopy, DMS Footprint, SHAPE assays
- Extensive experience with high-throughput sequencing and bioinformatics workflows for aptamer characterisation
- Well-versed in DNA/RNA folding, secondary structure prediction, and basic computational analysis tools
- Experience with display-based selection methods, such as bead-based, droplet-based, or cell-based platforms for aptamer screening
- Hands on experience of basic conjugation chemistries like NHS coupling, Click chemistry and solid phase oligo synthesis
Nice to have:
- Experience with Electrochemical/optical Aptamer based biosensor development
- Operating ability and basic analytical knowledge of standard instrument such as HPLC, FPLC, and LC-MS
Who You Are
- We value culture as much as we value technical expertise, creating an environment that’s equal parts collaboration, curiosity, and fun
We’re a fast-paced, mission-driven young team on a quest to make a lasting impact, fueled by uncompromising integrity, unwavering support for one another, and the thrill of exploring uncharted territories. Our passion for excellence drives everything we do, and we welcome individuals who share our commitment to shaping the future.
If our vision excites you, here are the qualities we look for:
- You live and breathe integrity, tackling challenges with honesty and transparency
- You’re a self-starter who loves diving into the unknown, collaborating on complex problems, and taking full ownership of results
- You excel at open, clear communication and see every piece of feedback as a springboard for growth—especially in a science and data-focused environment
- You’re motivated by creating real impact, particularly when it comes to advancing human health
- You strike a balance between independence and collaboration, knowing when to seek support or invite others to join in
- You’re confident in defending your ideas, while also valuing respectful, constructive debate as a path to better solutions
- You thrive in the dynamic atmosphere of a startup, constantly evolving your skill set and fearlessly applying what you learn
What We Offer
- A full-time role with a competitive salary and equity options, reflecting our value in your expertise and potential
- An environment where you’ll collaborate directly with the founding team at a leading biosensor startup, gaining access to industry experts and thought leaders
- The chance to grow with us, including ample opportunities for leadership, career advancement, and exploration
- Travel to New York and other potential sites for R&D purposes
- The excitement of working on cutting-edge technology, shaping strategic decisions, and driving innovation at an early-stage venture alongside a superstar team
Be Part of Our Journey
If you\’re ready to be at the forefront of biosensing innovation and thrive in fast-paced, learning-rich environments, we\’d love to hear from you.
If your skills and experience do not align perfectly with this role, yet you believe you have something unique to offer, we\’re keen to listen. Reach out to us with a short statement on how you can contribute and let\’s discuss where you might fit into our team.
Seniority level
-
Seniority level
Not Applicable
Employment type
-
Employment type
Full-time
Job function
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Job function
Research, Analyst, and Information Technology
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Industries
Software Development
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Aptamer Scientist employer: Level Zero Health
Contact Detail:
Level Zero Health Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Aptamer Scientist
✨Tip Number 1
Familiarise yourself with the latest advancements in biosensor technology and aptamer research. This will not only help you understand Level Zero's mission but also allow you to engage in meaningful conversations during interviews.
✨Tip Number 2
Network with professionals in the biosensing and health tech fields. Attend relevant conferences or webinars where you can meet potential colleagues and learn more about the industry trends that could benefit your application.
✨Tip Number 3
Showcase your hands-on experience with techniques like SELEX and binding analysis in informal discussions or networking events. Being able to discuss your practical skills confidently can set you apart from other candidates.
✨Tip Number 4
Prepare thoughtful questions about Level Zero's projects and future directions. This demonstrates your genuine interest in the role and helps you assess if the company culture aligns with your values.
We think you need these skills to ace Aptamer Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in molecular biology, biochemistry, and aptamer technology. Emphasise your expertise in SELEX, binding analysis, and any specific techniques mentioned in the job description.
Craft a Compelling Cover Letter: In your cover letter, express your passion for biosensor technology and how your background aligns with Level Zero's mission. Mention specific projects or experiences that demonstrate your skills in aptamer library design and data analysis.
Showcase Technical Skills: Clearly outline your technical skills related to the role, such as proficiency in Python or R for data analysis, and any experience with electrochemical aptamer-based biosensors. Use examples to illustrate your capabilities.
Highlight Collaborative Experience: Since the role involves working closely with a team, include examples of past collaborative projects. Discuss how you contributed to team success and how you value open communication and constructive feedback.
How to prepare for a job interview at Level Zero Health
✨Showcase Your Technical Expertise
Make sure to highlight your experience with SELEX, aptamer library design, and binding analysis techniques like SPR and BLI. Be prepared to discuss specific projects where you applied these skills, as this will demonstrate your hands-on knowledge and problem-solving abilities.
✨Demonstrate Data Analysis Skills
Since strong data analysis skills are required, be ready to talk about your proficiency with tools like Python or R. You might want to prepare examples of how you've used these tools in past projects to analyse experimental data and draw meaningful conclusions.
✨Emphasise Collaboration and Communication
Level Zero values open communication and teamwork. Be prepared to discuss how you've collaborated with others in previous roles, especially in a research setting. Highlight instances where you effectively communicated complex scientific concepts to non-experts.
✨Align with Company Culture
Familiarise yourself with Level Zero's mission and values. During the interview, express your enthusiasm for their vision of revolutionising health management and how your personal values align with their culture of integrity, curiosity, and collaboration.
