At a Glance
- Tasks: Support groundbreaking research on DNA replication stress and repair in a dynamic lab environment.
- Company: Join a leading research team funded by the Academy of Medical Sciences.
- Benefits: Gain hands-on experience, develop skills, and contribute to impactful scientific studies.
- Other info: Diverse and inclusive workplace with opportunities for personal and professional growth.
- Why this job: Be part of innovative research that makes a real difference in biomedical sciences.
- Qualifications: Bachelor’s degree in biomedicine or related field; lab experience preferred.
The predicted salary is between 35000 - 45000 £ per year.
- Research Laboratory Technician
- Biomedical & Life Sciences
Job Description
We are looking for a Research Technician to support our research studies exploring how a ubiquitin ligase contributes to DNA replication stress and repair.
The position is funded by an Academy of Medical Sciences grant awarded to Dr.
Panagiotis Kotsantis, and is available for 24 months.
Key Responsibilities
- Generate and characterise engineered cell lines with inducible gene expression, gene depletion, and targeted genetic modifications, including domain deletions and site‑directed mutations.
- Investigate cellular responses to DNA damage and replication stress using a range of molecular and cell biology approaches, including immunofluorescence microscopy, immunoblotting, DNA fibre assays, and micronucleus analysis.
- Examine protein localisation and chromatin‑associated dynamics at sites of DNA replication and genome maintenance using advanced imaging and proteomic techniques.
- Characterise protein–protein and protein–nucleic acid interactions through biochemical and proximity‑based assays, including immunoprecipitation and proximity ligation assays.
- Identify and analyse interaction networks and candidate substrates of a target pathway regulator using mass spectrometry‑based proteomics.
- Prepare and conduct experiments including engineered cell line generation, DNA damage response analysis, protein interaction and localisation studies, and proteomic identification of molecular interaction networks.
- Data acquisition and management, and contributing to analysis and reporting.
- Support day‑to‑day lab operations, including equipment maintenance, ordering supplies, record keeping, and assisting with regulatory documentation.
- Provide technical training to students and other lab members.
About You
- Bachelor’s degree in biomedicine, biomedical sciences, biochemistry or a related discipline.
- Experience supporting biomedical studies, including mammalian cell culture, immunoblotting, immunofluorescence, DNA cloning, molecular biology techniques and data analysis using Graph Pad‑Prism and Image J.
- Strong organisational and administrative skills, including inventory management, maintaining accurate records, and report writing.
- A proactive approach to problem‑solving and technical troubleshooting, with the confidence to take initiative and work independently.
- Excellent written and verbal communication skills, and a collaborative, team‑oriented approach.
- Experience with the DNA fibre assay is desirable but not essential; training will be provided for the right candidate.
Most importantly, you will bring motivation, attention to detail, and enthusiasm for contributing to meaningful interdisciplinary research.
We warmly welcome applicants from all sections of the community regardless of their age, religion, gender identity or expression, race, disability or sexual orientation, and are committed to promoting diversity and equality of opportunity.
Contact
Please contact Dr Panagiotis Kotsantis at p. kotsantis@lancaster. ac. uk .
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Research Laboratory Technician - 0607-26 employer: Lancaster University
Lancaster University is an exceptional employer, offering a dynamic and inclusive work environment that prioritises student wellbeing and success. With a strong commitment to professional development, employees benefit from flexible working arrangements and opportunities to lead impactful initiatives in widening participation. Located in the vibrant city of Lancaster, staff enjoy a supportive culture that values diversity and fosters collaboration across disciplines.
StudySmarter Expert Advice🤫
We think this is how you could land Research Laboratory Technician - 0607-26
✨Join Biotechnology Meetups
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✨Tap into University Resources
If you’re still in school or recently graduated, don’t forget to use your university’s career services. They often have exclusive connections with companies looking for temporary staff. Reach out to them for internship listings and networking opportunities tailored to the biotech sector.
✨Apply Directly on Our Website
When you spot that perfect temporary role at Lancaster University, make sure to apply directly through our website. This way, you’ll be in the best position to get noticed quickly and can show your enthusiasm for the role while filling out the application.
We think you need these skills to ace Research Laboratory Technician - 0607-26
Some tips for your application 🫡
Showcase Relevant Lab Skills:In the biotech world, your lab skills are paramount. Make sure your CV highlights specific techniques and equipment you’ve used, such as PCR, gel electrophoresis, or cell culture. This will give us a clear picture of what you can bring to Lancaster University as a temporary teammate.
Highlight Your Research Experience:If you’ve worked on any research projects — whether during your studies or in previous positions — make sure to detail these in your application. Include the objective, your role, and what you achieved. This will help us see your potential and fit for the temporary position at Lancaster University.
Keep It Concise and Relevant:Especially for a temporary role, we want to see a clear and focused application. Tailor your CV and cover letter to emphasise the qualifications and experiences that are most relevant to the biotech field and the specific role at Lancaster University. This shows us you’re genuinely interested and capable.
Be Clear About Your Availability:Since it’s a temporary role, let us know right away when you’re available to start and how long you can commit. Include this in your cover letter — this kind of transparency saves us all time and helps us find the right fit quickly at Lancaster University.
How to prepare for a job interview at Lancaster University
✨Brush Up on Your Biotech Basics
Understanding the fundamental concepts in biotechnology is crucial. Be ready to discuss core topics like genetics, molecular biology, or bioinformatics, especially if you're asked technical questions. We suggest revisiting your coursework or recent projects to refresh your memory.
✨Demonstrate Your Adaptability
Since this is a temporary role, they’re likely looking for someone who can jump in and get up to speed quickly. Share experiences where you’ve adapted to new environments, tools, or teams in a short space of time. It shows you're ready to tackle the challenge head-on!
✨Emphasise Your Lab Experience
If you’ve got hands-on experience in lab settings, now’s the time to showcase it. Talk about specific techniques you’ve mastered, like PCR or chromatography, and any relevant safety protocols you’ve followed. These details help paint you as an effective team member from day one.
✨Be Prepared to Explain Your Passion
Hiring managers want to see your motivation, especially for a temporary position in a fast-paced field like biotechnology. Be ready to discuss what excites you about the industry, your career goals, and how this role at Lancaster University aligns with them. It’s all about showing that you’re not just looking for a job, but a stepping stone in your biotech journey.
