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For Companies At a Glance
- Tasks: Lead GMP manufacturing of CAR-T cells for groundbreaking cancer research.
- Company: Join King’s College London and NHS Trusts in pioneering medical advancements.
- Benefits: Fixed-term contract, professional development days, and a collaborative work environment.
- Why this job: Make a real difference in patients' lives with innovative CAR-T therapies.
- Qualifications: Experience in GMP manufacturing, flow cytometry, and knowledge of immunology required.
- Other info: Be part of a rapidly expanding academic programme with excellent career growth.
The predicted salary is between 36000 - 60000 £ per year.
About Us
King’s College London (KCL) and its partner NHS Trusts – King’s College Hospital (KCH) and Guy’s & St Thomas’ Hospital (GSTT) together have one of the largest chimeric antigen receptor T (CAR-T) cell programmes in the UK with licensed and experimental CAR-T products being administered for patients with B-cell leukaemias, lymphomas, multiple myeloma, solid tumours and autoimmune disease.
About The Role
This role is to lead GMP manufacturing of CAR-T cells for a Blood Cancer UK funded, first-in-human, multi-centre CAR-T study for relapsed refractory multiple myeloma (TriMM trial) due to open at the lead site King’s College Hospital in 2026. The postholder will join a team of CAR-T cell production scientists and technicians based at KCL, Denmark Hill campus and work across GMP facilities at GSTT and KCH in close collaboration with the pre-clinical, process development and Haematology clinical teams.
The Advanced Therapy GMP Unit at GSTT is purpose built for the manufacture of Advanced Therapy Investigational Medicinal Products (ATIMPs) such as somatic cell therapies, gene therapies and tissue engineered products for early phase clinical trials. The Cell Therapy Unit at KCH (King’s CTU) offers GMP manufacturing facilities for cell and gene therapy products, including lenti/retroviral vectors, hepatocytes, islet cells, mesenchymal stromal cells and CAR-T cells. The postholder will have a strong background in GMP manufacturing of ATIMPs, be proficient in flow cytometry, have prior experience with clinical trials, and an in-depth knowledge of immunology and CAR-T cell biology.
This is an excellent opportunity for an experienced production scientist to join a rapidly expanding academic CAR-T programme at King’s Health Partners and contribute to innovative research enabling patients with refractory cancers to be treated with potentially transformative CAR-T therapy products.
This is a full time post (35 hours per week), and you will be offered a fixed term contract until 31/05/2028.
Research staff at King’s are entitled to at least 10 days per year (pro-rata) for professional development.
Advanced Therapies Production Scientist/Research Associate - Strand, London, WC2R 2LS employer: KINGS COLLEGE LONDON
Contact Detail:
KINGS COLLEGE LONDON Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Advanced Therapies Production Scientist/Research Associate - Strand, London, WC2R 2LS
✨Tip Number 1
Network like a pro! Reach out to people in the industry, attend events, and connect with professionals on LinkedIn. We can’t stress enough how valuable personal connections can be in landing that dream job.
✨Tip Number 2
Prepare for interviews by researching the company and role thoroughly. We recommend practising common interview questions and even doing mock interviews with friends or mentors to boost your confidence.
✨Tip Number 3
Showcase your skills! Bring along a portfolio or examples of your work to interviews. We love seeing tangible evidence of what you can do, especially in a hands-on field like CAR-T cell production.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen. Plus, we’re always looking for passionate individuals who want to make a difference in advanced therapies.
We think you need these skills to ace Advanced Therapies Production Scientist/Research Associate - Strand, London, WC2R 2LS
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the role of Advanced Therapies Production Scientist. Highlight your experience in GMP manufacturing and any relevant clinical trials you've been involved in. We want to see how your background aligns with our CAR-T cell programme!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about CAR-T therapy and how your skills can contribute to our innovative research. Keep it concise but impactful – we love a good story!
Showcase Relevant Skills: Don’t forget to showcase your proficiency in flow cytometry and your knowledge of immunology and CAR-T cell biology. These are key skills for us, so make sure they stand out in your application!
Apply Through Our Website: We encourage you to apply through our website for a smooth application process. It’s the best way for us to receive your application and ensure it gets the attention it deserves. Good luck!
How to prepare for a job interview at KINGS COLLEGE LONDON
✨Know Your CAR-T Inside Out
Make sure you brush up on your knowledge of CAR-T cell biology and the specific therapies being developed at King’s College London. Being able to discuss the nuances of CAR-T therapy, especially in relation to multiple myeloma, will show your passion and expertise.
✨Familiarise Yourself with GMP Standards
Since this role involves GMP manufacturing, it’s crucial to understand the regulations and standards that govern this process. Be prepared to discuss your previous experiences with GMP and how you’ve ensured compliance in past roles.
✨Highlight Your Teamwork Skills
This position requires collaboration with various teams, so be ready to share examples of how you've successfully worked in multidisciplinary teams. Emphasise your communication skills and how you can contribute to a cohesive working environment.
✨Prepare Questions for Them
Interviews are a two-way street! Prepare insightful questions about the TriMM trial and the future of CAR-T therapies at King’s. This shows your genuine interest in the role and helps you assess if it’s the right fit for you.
