Clinical Data Manager - Real-World Evidence - Observational and Disease Registry studies
Location: UK / Remote
Permanent
**MUST HAVE RWE and registry or observational study experience**
KEMIO is looking for an experienced Clinical Data Manager to join a growing Healthcare and Data Analytics Life Sciences organisation delivering observational clinical studies and real-world evidence programmes, with a particular focus on oncology and rare disease.
This is a hands-on role where you'll take ownership of clinical data management activities across Phase II-IV studies, working closely with Clinical Operations, Biometrics, Data Science and Sponsor teams.
What you'll be doing
- Develop and maintain Data Management Plans (DMPs) and data validation specifications
- Support eCRF/EDC design and clinical database development
- Lead data review, cleaning, validation and site query management
- Manage clinical coding including MedDRA and WHO Drug
- Support adverse event/SAE reconciliation and safety data requirements
- Work with multiple data sources including eCOA/ePRO, laboratory, biomarker, EHR, omics and wearable data
- Coordinate data transfers and integrations
- Manage activities through to Database Lock
- Produce data management metrics and KPIs
- Work closely with internal teams and external Sponsors to ensure high-quality, compliant data delivery
What we're looking for
You’ll have 5+ years' clinical data management experience, ideally gained within pharma, biotech, CRO or a clinical research environment.
You’ll bring strong experience across:
- Phase II-IV clinical studies
- Clinical data review, cleaning and validation
- EDC/eCRF design and edit checks
- MedDRA and WHO Drug coding
- Safety data and SAE reconciliation
- Taking clinical databases through to database lock
- Working within ICH-GCP and relevant regulatory requirements
Experience within oncology and/or rare disease would be particularly valuable.
We’re looking for someone who can work independently, take ownership of their studies and communicate confidently with both internal teams and Sponsor stakeholders.
Senior Clinical Data Manager - RWE - UK Remote employer: KEMIO Consulting
KEMIO Consulting is an exceptional employer, offering a dynamic work culture that fosters innovation and collaboration in the heart of London. With a strong emphasis on employee growth, you will have the opportunity to mentor fellow engineers while leading transformative MLOps initiatives in biomedicine. The company provides a supportive environment that values cutting-edge technology and encourages professional development, making it an ideal place for those seeking meaningful and rewarding careers.
