At a Glance
- Tasks: Develop predictive models of epigenetic dynamics and collaborate with top researchers.
- Company: Join the prestigious John Innes Centre at Oxford University.
- Benefits: Access to cutting-edge technology, training opportunities, and a supportive research environment.
- Other info: Work in an interdisciplinary team with excellent career advancement potential.
- Why this job: Make a real impact in understanding fundamental biological processes.
- Qualifications: PhD in Theoretical Physics, Bio-Mathematics, or Computational Biology preferred.
The predicted salary is between 36000 - 60000 £ per year.
Overview
The main purpose of the position is to develop predictive computational models of epigenetic dynamics, collaborating with the experimental group of Prof Rob Klose in the Dept of Biochemistry, Oxford University. The models will enhance understanding of how the Polycomb system silences gene expression and how a silenced memory state can be stably maintained through many cell cycles. The position is funded by Wellcome and would suit an individual with a high degree of independence and vision, able to advance the project independently. The successful candidate will have a rare opportunity to work on fundamental biological processes in an interdisciplinary environment, with seamless collaboration with a leading experimental group.
The ideal candidate will possess (or soon complete) a PhD in Theoretical Physics, Bio-Mathematics or Computational Biology. They will possess a strong interest in biological problems and have achieved demonstrable scientific success in previous roles. Prior experience of biological modelling is desirable but not essential.
Languages: ENGLISH
About the John Innes Centre
The John Innes Centre is an independent, international centre of excellence in plant and microbial sciences. We nurture a creative, curiosity-led approach to answering fundamental questions in bioscience, and translate that knowledge into societal benefits. Our strategic vision, Healthy Plants, Healthy People, Healthy Planet, sets out our ambitious long-term goals for the game changing impact of our science globally. Our employees enjoy access to state-of-the-art technology and a diverse range of specialist training opportunities, including support for leadership and management. Click here to find out more about working at the John Innes Centre.
About the Howard Group
The Howard group combines simple, predictive mathematical and biophysical modelling with long-lasting experimental collaborations to dissect biological mechanisms too complex to unravel by experiments alone. In many cases we are able to rationalise complex biological dynamics into simple underlying mechanisms, with few components and interactions.
Our approach is highly interdisciplinary and relies heavily on the techniques of statistical physics and applied mathematics, as well as on close collaboration with experimental groups. At present there are two main research areas in the group: probing how epigenetic memory states are set up and then stably maintained, and understanding patterning dynamics in sub-cellular biological systems. For epigenetics, we work on both histone modification memory systems, particularly the Polycomb silencing system, as well as on DNA methylation. For patterning, the main application at present is to the dynamics of crossover positioning in meiosis.
The group regularly publishes in the most prominent multidisciplinary journals, with recent papers in Nature, Science, Cell Systems, eLife, Molecular Cell and PNAS. Several previous members of the Howard group now hold independent faculty positions of their own, including in Warwick, Glasgow, Sydney, Amsterdam and Munich.
Job offer Postdoctoral Researcher employer: John Innes Centre
The John Innes Centre offers an exceptional environment for a Postdoctoral Researcher, fostering a culture of creativity and collaboration in the heart of Oxford. With access to cutting-edge technology and a commitment to employee development through diverse training opportunities, you will be part of a pioneering team dedicated to advancing our understanding of epigenetic dynamics. This role not only provides a unique chance to contribute to impactful research but also positions you within a vibrant academic community that values independence and innovation.
StudySmarter Expert Advice🤫
We think this is how you could land Job offer Postdoctoral Researcher
✨Tip Number 1
Network like a pro! Reach out to current or former researchers in the field, especially those connected to the John Innes Centre or Prof Rob Klose's group. A friendly chat can give you insights and maybe even a foot in the door.
✨Tip Number 2
Show off your skills! Prepare a short presentation or a portfolio of your previous work that highlights your computational modelling expertise. This will help you stand out during interviews and discussions.
✨Tip Number 3
Be proactive! Don’t just wait for job openings; reach out directly to the team at the John Innes Centre. Express your interest in their research and how you can contribute. It shows initiative and enthusiasm!
✨Tip Number 4
Keep learning! Stay updated on the latest trends in epigenetics and computational biology. Join relevant webinars or workshops to expand your knowledge and meet like-minded individuals in the field.
We think you need these skills to ace Job offer Postdoctoral Researcher
Some tips for your application 🫡
Tailor Your Application:Make sure to customise your CV and cover letter for the Postdoctoral Researcher role. Highlight your relevant experience in computational modelling and any interdisciplinary projects you've worked on. We want to see how your background aligns with our research focus!
Show Your Passion:Let your enthusiasm for biological problems shine through in your application. Share specific examples of how you've tackled complex scientific challenges in the past. We love candidates who are genuinely excited about the work we do at StudySmarter!
Be Clear and Concise:When writing your application, keep it straightforward and to the point. Use clear language to describe your skills and experiences. We appreciate well-structured applications that make it easy for us to see your qualifications at a glance.
Apply Through Our Website:Don’t forget to submit your application through our official website! This ensures that your application gets to the right people quickly. Plus, it’s the best way to stay updated on your application status. We can’t wait to hear from you!
How to prepare for a job interview at John Innes Centre
✨Know Your Science
Make sure you brush up on the latest research in epigenetics and computational biology. Familiarise yourself with the Polycomb system and its role in gene expression. Being able to discuss recent papers or breakthroughs will show your genuine interest and expertise.
✨Show Your Independence
Since the position requires a high degree of independence, prepare examples from your past work where you took initiative or led a project. Highlight how you approached challenges and what outcomes you achieved, demonstrating your ability to advance projects independently.
✨Interdisciplinary Mindset
This role is all about collaboration across disciplines. Be ready to discuss how your background in theoretical physics, bio-mathematics, or computational biology can contribute to the experimental work at the John Innes Centre. Show that you can bridge the gap between theory and practice.
✨Ask Insightful Questions
Prepare thoughtful questions about the Howard group's current research areas and future directions. This not only shows your enthusiasm but also your critical thinking skills. Asking about their approach to biological modelling can spark a great conversation and demonstrate your engagement.
