Senior Scientist - Allegis Global Solutions in Stevenage

GSK is a science-led global healthcare company with a special purpose: to help people do more, feel better, live longer. We are on an audacious journey to impact the health of 2.5 billion people over the next decade. Our R&D division is at the forefront of this mission, dedicated to the discovery and development of groundbreaking vaccines and medicines. We are transforming the landscape of medical research by integrating cutting-edge science and technology and harnessing the power of genetics and new data. By fostering a collaborative environment that unites the talents of our people, we are revolutionizing R&D to pre-empt and defeat diseases.

Location: Stevenage

Contract length: 12 months

Part of R&D, Large Molecule Research is accountable for the discovery of antibodies and other protein-based therapeutics from the initial discovery, expression and characterisation to molecular engineering and biophysical profiling. Within Large Molecule Research, the Molecular Design and Engineering (MDE) group is responsible for antibody engineering and developability profiling to improve molecule quality and transform discovered leads into potential therapeutics before candidate selection.

We are seeking an Analytical Scientist to join the developability team within MDE. The role will be lab centric and will involve profiling/characterising a panel of biopharmaceuticals based on their biophysical properties, interpreting the data and conveying the outcomes to early project teams. The successful candidate will have experience with one or more of the biophysical techniques such as Dynamic light scattering, analytical size exclusion, differential scanning fluorimetry etc. and ideally have applied these to characterise the stability and/or structure of proteins. Although predominantly lab based, the role will also require effective communication (both written and oral), organisational, interpersonal and teamwork skills.

Key Responsibilities

• Plan, design, and execute experiments to characterise proteins using biophysical methods, such as SEC, DLS and DSF.
• Communicate experimental outcomes to non-experts on multi-disciplinary project teams.
• Keep high quality electronic lab notebooks.

Minimum Requirements

• PhD or equivalent academic/industry experience in biophysics or related discipline.
• Demonstrated, hands-on experience characterising proteins using one or more of the following biophysical techniques: Dynamic Light Scattering, Analytical Size Exclusion or other chromatography based methods, Differential scanning fluorimetry, mass spectrometry etc.
• Good analytical and data interpretation skills.

Preferred Qualifications

• Experience in working with automated liquid handlers.
• Familiarity with antibody drug discovery processes.
• Experience characterising protein-protein interactions using surface plasmon resonance.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

Inclusion at GSK

GSK is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.