At a Glance
- Tasks: Lead groundbreaking research on the ERG transcription factor in lymphatic biology.
- Company: Join a prestigious partnership between Imperial College London and the University of Nottingham.
- Benefits: Enjoy a competitive salary, 41 days annual leave, and career development support.
- Other info: Collaborative environment with opportunities for scientific recognition and career advancement.
- Why this job: Make a real impact on patient care through innovative research and cutting-edge technology.
- Qualifications: Experience in in vivo models, high-resolution imaging, and molecular biology techniques.
The predicted salary is between 40000 - 50000 £ per year.
As a MRC-funded Postdoctoral Research Associate you will spearhead an innovative investigation into the transcription factor ERG to determine its role as a master regulator of lymphatic identity and immune response. Working at a world-leading institution within a high-impact collaborative environment, you will employ in vivo models with state of the art molecular and cellular assays to uncover how ERG functions as an "immune gatekeeper" during both steady state and inflammatory challenges. Ultimately, your findings will define a new roadmap for therapeutic targets to treat debilitating conditions like primary lymphoedema, directly bridging the gap between fundamental molecular science and patient benefit.
In this role, you will lead investigations into how the transcription factor ERG regulates lymphatic identity and immune cell trafficking. Your responsibilities will include performing in vivo functional assays to quantify lymphatic drainage and immune cell trafficking. You will utilize single cell transcriptomics and high resolution multiplexed imaging to map cellular landscapes in mouse and human tissues. Additionally, you will conduct mechanistic studies to identify the role of ERG in lymph node maintenance. Throughout, you will develop advanced analytical skills and benefit from a dynamic and collaborative research environment.
What we are looking for:
- In Vivo Expertise: Advanced techniques using genetically modified mice, including functional lymphatic assays and immune trafficking models.
- High Resolution Imaging: Proficiency in spatially resolved multiplexed imaging and confocal whole mount tissue analysis.
- scRNA seq: Experience designing 10x Genomics experiments and performing computational data analysis.
- Molecular Biology: Skills in CRISPR/siRNA inhibition and in vitro functional assays.
- Data Analysis: Ability to interpret high dimensional datasets to identify gene signatures and cellular interactions.
- Collaborative Mindset: Proactive approach to sharing expertise and publishing high quality manuscripts.
- Ambition: Driven to acquire new skills and develop an independent academic research career.
What we can offer you:
- High Impact Collaboration: Work across a unique partnership between Imperial College London and the University of Nottingham, gaining expertise in ERG transcriptional regulation and immune response.
- Cutting Edge Technology: Gain mastery of state of the art platforms, including 10x Genomics for single cell transcriptomics and spatially resolved multiplexed imaging.
- Translational Impact: Contribute to clinically relevant research alongside City St. George's to identify therapeutic targets for conditions like primary lymphoedema.
- Scientific Recognition: Lead the dissemination of findings through high quality manuscripts and international conference presentations.
- Leading Benefits: Receive a sector leading salary and 41 days of annual leave.
- Career Structure: This 36 month post provides dedicated support to develop independent research ideas for future senior academic roles.
This is a Full time fixed term (3 years) role based at our White City Campus (Hammersmith Hospital site).
Research Associate in Lymphatic Biology employer: Job Search Place Limited
As a leading research institution, we offer an exceptional environment for the Research Associate in Lymphatic Biology role, where collaboration with top-tier partners like Imperial College London and the University of Nottingham fosters innovation and scientific excellence. Our commitment to employee growth is evident through dedicated support for developing independent research ideas, alongside access to cutting-edge technology and a generous benefits package, including a sector-leading salary and 41 days of annual leave. Join us at our White City Campus, where your contributions will directly impact therapeutic advancements for conditions such as primary lymphoedema.
StudySmarter Expert Advice🤫
We think this is how you could land Research Associate in Lymphatic Biology
✨Get Involved in Research Communities
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We think you need these skills to ace Research Associate in Lymphatic Biology
Some tips for your application 🫡
Highlight Your Research Experience:When applying for a full-time role in scientific research, make sure to emphasise your research experience prominently in your CV. Share specific projects you’ve worked on, the methodologies you used, and any significant findings. If you’ve published papers or presented at conferences, definitely include that too – it shows you’re on it in the academic world!
Tailor Your Cover Letter to the Research Area:Your cover letter should reflect your passion for the specific area of research at Job Search Place Limited. Mention relevant experiences that align with the organisation’s goals or projects. This shows that you’ve done your homework and are genuinely interested in the position – plus, it helps us see how you’d fit into the team dynamics.
Showcase Your Data Analysis Skills:In scientific research, data analysis skills are a big deal! Make sure to detail any relevant analytical tools or software you’re familiar with, like R, Python, or statistical packages. Employers are keen to know you can handle the data-heavy elements of the role, so add specific examples where you’ve used these skills effectively.
Discuss Your Future Research Goals:In your motivation section, it’s a great idea to talk about your future research goals and how they align with the work being done at Job Search Place Limited. This shows that you’re not just looking for any job, but rather a chance to contribute meaningfully to the field. We love to see applicants who are forward-thinking and enthusiastic about their research journey!
How to prepare for a job interview at Job Search Place Limited
✨Showcase Your Research Skills
In scientific research, it’s crucial to demonstrate your ability to design and conduct experiments. Come armed with examples of past projects where you've developed hypotheses, collected data, and analysed results. Be ready to discuss any specific methodologies or tools you’ve used, like PCR techniques or statistical software.
✨Prepare for Technical Questions
Expect some technical questions specific to your field. Make sure you're up to speed with recent advancements in scientific research related to the role at Job Search Place Limited. Brush up on concepts relevant to their projects and be prepared to discuss how you would approach a specific research problem or challenge they might face.
✨Know Your Publications
If you've authored or co-authored any papers, be prepared to discuss them! Highlighting your contributions to published research can really set you apart. It shows not only your expertise but also your ability to communicate complex ideas clearly, which is key in scientific research roles.
✨Exhibit Your Team Spirit
In full-time roles, collaboration is often at the heart of scientific research. Prepare examples that show how you've successfully worked in teams, dealt with conflicts, or contributed to group projects. We want to know how you can work effectively with the team at Job Search Place Limited to drive research projects forward.
