At a Glance
- Tasks: Daily production of PET radiopharmaceuticals and maintenance of production equipment.
- Company: Join the Radiopharmacy team at Alliance Medical, a leader in radiopharmaceuticals.
- Benefits: Full-time position with shift work, including night shifts on a rotational basis.
- Other info: Role requires adherence to strict safety and regulatory protocols.
- Why this job: Opportunity to work in a GMP environment with cutting-edge radiochemistry.
- Qualifications: Degree in a scientific discipline and experience in GMP and radiochemistry preferred.
The predicted salary is between 30000 - 40000 £ per year.
We have a new opportunity for a Production Radiochemist to join our Radiopharmacy team. This is a full‑time position working 40 hours a week. Our site’s operational hours are 00:00 to 20:00, 24 days a week, so shift work is required.
You should be a scientific graduate with a scientific background, ideally with experience of (radio) pharmaceutical manufacture in a GMP environment. To be successful in this role you will demonstrate:
- Excellent verbal and written communication skills
- Analytical skills
- A logical approach to problem solving
- Good attention to detail
As an effective team member you will have great organisational skills and the ability to work under pressure. Be educated to a degree level in a related scientific discipline or able to demonstrate relevant experience. Ideally be able to demonstrate experience in radiochemistry or related disciplines. Ideally be able to demonstrate knowledge of GMP, validation and relevant regulations. Validation experience (including laboratory equipment and process validation) would be advantageous. Previous experience operating in a GMP grade C cleanroom, operating a GMP grade A isolator and/or distributing radiopharmaceuticals would be advantageous.
Production involves daily routine production of PET radiopharmaceuticals, including 18F‑FDG, for Alliance Medical Radiopharmacy in strict adherence to GMP and relevant EU pharmacopoeia standards. You will operate routine protocols for customer orders and distribute 18FDG and other PET tracers to scanning sites.
Maintenance includes arranging first‑line scheduled and emergency maintenance for production equipment and associated plant, in collaboration with Alliance Medical Radiopharmacy engineers. You will ensure efficient performance of, and undertake first‑line maintenance and any required troubleshooting of the FDG synthesizers, dispensing equipment, hot cells, including dose calibration, monitoring and sterility checks within strict application of environmental and clean‑room protocols.
For faults, you will maintain records of faults on any dysfunction – operational, equipment or environmental integrity. You will interpret and rectify operational faults where possible and liaise with engineers and suppliers as necessary.
Quality Systems require you to operate to approved quality standards by recording production‑quality related actions (e.g., deviations and change controls) in a timely manner, to comply with AMR policies and regulatory requirements.
As a Principal Operator, on a rota basis you will act as production radiochemist for radio‑synthesis of PET tracers in accordance with a pre‑determined daily timetable. The role will include some night work on a rotational shift rota.
Chemical Preparation involves monitoring and maintaining lab stocks of chemicals, consumables and spare parts, as well as the safe disposal of waste chemicals and materials.
Standard Operating Procedures require you to prepare and review SOPs in accordance with the relevant guidelines for approval by the QP and adoption by the unit.
Training Others involves providing training and support for others selected as rota/backup in production of radiopharmaceuticals.
Safety and Control means assuming responsibility for the safe and efficient handling of all radioactive substances (solid, gas, liquid) received from the Centre’s cyclotron, including their synthesis, transmission, dispensing, storage, containerisation, packing, dispatch, transport, decay control and release. In accordance with local rules for emergency or serious incident procedure, you will record such events in accordance with SOPs. You will be responsible for following agreed safety procedures to ensure safety of yourself and others.
Regulatory compliance requires strictly adhering to GMP, GLP and safety protocols laid down by the MHRA, EA and HSE in accordance with issued licences as determined from time to time. Corresponding adherence to local rules developed by Alliance Medical Radiopharmacy in conformity with such licensing requirements is also necessary.
Production Radiochemist employer: Job Search Place Limited
Alliance Medical Radiopharmacy is located in a state-of-the-art facility. Employees benefit from comprehensive training and support in a dynamic team environment focused on quality and safety. The company is committed to adhering to the highest standards in radiopharmaceutical production.
