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- Tasks: Lead innovative projects in drug discovery and develop novel therapeutic agents.
- Company: Join a dynamic biopharmaceutical company focused on patient-driven solutions.
- Benefits: Competitive salary, professional development, and opportunities for mentorship.
- Why this job: Make a real impact in oncology and neuroscience while advancing your career.
- Qualifications: MSc/PhD in relevant field with expertise in molecular modelling and drug design.
- Other info: Collaborative environment with excellent growth opportunities and cutting-edge technology.
The predicted salary is between 72000 - 108000 £ per year.
We are looking for dynamic, creative, and talented computational chemist to join our expanding Discovery & Medicinal Chemistry Department. Reporting to the Director of Medicinal Chemistry, you will apply your expertise, leadership and guidance to discover and develop novel small-molecule therapeutic agents. You will be working within a patient-focused, science-driven, and multi-disciplinary biopharmaceutical environment, covering all stages of the drug discovery process. You will collaborate with scientists from other disciplines within Jazz Pharmaceuticals and with external collaborators to build an innovative portfolio of therapeutics across our exciting and growing oncology and neuroscience pipelines. Working at the forefront of drug discovery you will advance projects from target selection to preclinical drug candidates and FiH trials, and contribute to the growth of the medicinal chemistry team.
Key Responsibilities
- Utilize modern molecular modelling methods to support different stages of R&D programs.
- Collaborate effectively with other departments and functions to advance research discovery projects expeditiously from hit identification to high quality preclinical candidates.
- Design, lead and drive computational studies on projects throughout the several discovery phases and ensure execution on agreed deliverables.
- Opportunities to lead or co-lead projects in addition to drive discipline-specific endeavours.
- Set the vision and strategy for computational chemistry.
- Foster innovative thinking in all areas of departmental activities, with a particular focus on computational and medicinal chemistry.
- Manage CRO compchem activities, providing expertise and guidance.
- Present plans and results internally, including at board level, and externally at conferences.
- Contribute to the writing of patent applications, scientific publications, and internal reports.
- Develop and mentor less experienced staff.
- Keep up to date with the latest scientific advances and trends in drug discovery to deliver the next-generation therapies.
- Undertake ongoing professional development by attending relevant training and conferences.
Requirements & Qualifications
- MSc/PhD in a relevant scientific discipline (Pharmaceutical Sciences, Chemistry, Computational Chemistry) with a solid foundation in molecular modelling built in a pharma/biotech/CRO setting.
- Expert knowledge in CADD software packages and modern molecular modelling techniques.
- Sound knowledge in cutting-edge cheminformatic tools, AI/ML-enabled technologies, and in silico drug design, including both structure- and ligand-based methodologies.
- Passion for drug discovery with a deep entrepreneurial and problem-solving attitude.
- Mastery of all the theoretical and practical principles of medicinal chemistry and drug design.
- Broad knowledge of biophysical, biochemical, and cell-based assays used in the early stages of the drug discovery process.
- In depth understanding of multi-parameter optimization and ability to integrate disease biology, ADME/DMPK and toxicology data to solve complex drug discovery problems.
- Excellent leadership, management, organizational and team-working skills, and a talent to deliver project milestones within the expected time frame.
- Demonstrated track record of scientific publications.
- Exceptional oral, written, and interpersonal communication skills, and ability to develop and grow strong cross-functional collaborations.
Senior Principal Scientist, Computational Chemist employer: Jazz Pharmaceuticals
Contact Detail:
Jazz Pharmaceuticals Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Principal Scientist, Computational Chemist
✨Network Like a Pro
Get out there and connect with people in the industry! Attend conferences, workshops, or even local meetups. We can’t stress enough how important it is to build relationships; you never know who might have the inside scoop on job openings.
✨Show Off Your Skills
When you get the chance to chat with potential employers, make sure to highlight your expertise in computational chemistry and drug discovery. Share specific examples of your past projects and how you’ve contributed to successful outcomes. We want to see your passion shine through!
✨Follow Up
After any interview or networking event, don’t forget to follow up with a thank-you email. It’s a simple way to show appreciation and keep yourself fresh in their minds. We believe this small gesture can make a big difference!
✨Apply Through Our Website
If you’re keen on joining us at Jazz Pharmaceuticals, make sure to apply directly through our website. It’s the best way to ensure your application gets seen by the right people. Plus, we love seeing candidates who are proactive about their job search!
We think you need these skills to ace Senior Principal Scientist, Computational Chemist
Some tips for your application 🫡
Show Your Passion: When writing your application, let your enthusiasm for drug discovery shine through. We want to see your passion for computational chemistry and how it drives you to innovate and solve complex problems.
Tailor Your CV: Make sure your CV is tailored to highlight your relevant experience in molecular modelling and drug discovery. We love seeing how your background aligns with our needs, so don’t hold back on showcasing your achievements!
Craft a Compelling Cover Letter: Your cover letter is your chance to tell us why you're the perfect fit for the role. Be creative and specific about your experiences and how they relate to the responsibilities outlined in the job description.
Apply Through Our Website: We encourage you to apply directly through our website. It’s the best way to ensure your application gets into the right hands and shows us you’re serious about joining our team at StudySmarter!
How to prepare for a job interview at Jazz Pharmaceuticals
✨Know Your Science
Make sure you brush up on the latest advancements in computational chemistry and drug discovery. Be ready to discuss specific molecular modelling methods and how they apply to the role. This shows your passion and expertise, which is crucial for a Senior Principal Scientist.
✨Showcase Collaboration Skills
Since this role involves working with various departments, prepare examples of past collaborations. Highlight how you’ve effectively communicated and driven projects forward with cross-functional teams. This will demonstrate your ability to foster innovative thinking and teamwork.
✨Prepare for Leadership Questions
Expect questions about your leadership style and experiences. Think of instances where you’ve led projects or mentored others. Articulate how you set visions and strategies, as well as how you manage and motivate your team to achieve project milestones.
✨Practice Your Presentation Skills
You might need to present your plans and results during the interview. Practise summarising complex scientific concepts clearly and concisely. This will not only help you in the interview but also reflect your ability to communicate effectively at board level and conferences.