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- Tasks: Lead innovative projects in drug discovery and develop novel therapeutic agents.
- Company: Join Jazz Pharmaceuticals, a dynamic biopharmaceutical company focused on patient-driven solutions.
- Benefits: Competitive salary, professional development, and opportunities for impactful work.
- Why this job: Make a real difference in healthcare by advancing cutting-edge therapies.
- Qualifications: MSc/PhD in relevant field with expertise in molecular modelling and drug design.
- Other info: Collaborative environment with excellent growth opportunities and mentorship.
The predicted salary is between 72000 - 108000 £ per year.
We are looking for dynamic, creative, and talented computational chemists to join our expanding Discovery & Medicinal Chemistry Department. Reporting to the Director of Medicinal Chemistry, you will apply your expertise, leadership and guidance to discover and develop novel small-molecule therapeutic agents. You will be working within a patient-focused, science-driven, and multi-disciplinary biopharmaceutical environment, covering all stages of the drug discovery process. You will collaborate with scientists from other disciplines within Jazz Pharmaceuticals and with external collaborators to build an innovative portfolio of therapeutics across our exciting and growing oncology and neuroscience pipelines. Working at the forefront of drug discovery you will advance projects from target selection to preclinical drug candidates and FiH trials, and contribute to the growth of the medicinal chemistry team.
Responsibilities
- Utilize modern molecular modelling methods to support different stages of R&D programs;
- Collaborate effectively with other departments and functions to advance research discovery projects expeditiously from hit identification to high quality preclinical candidates;
- Design, lead and drive computational studies on projects throughout the several discovery phases and ensure execution on agreed deliverables;
- Opportunities to lead or co-lead projects in addition to drive discipline-specific endeavours;
- Set the vision and strategy for computational chemistry;
- Foster innovative thinking in all areas of departmental activities, with a particular focus on computational and medicinal chemistry;
- Manage CRO compchem activities, providing expertise and guidance;
- Present plans and results internally, including at board level, and externally at conferences;
- Contribute to the writing of patent applications, scientific publications, and internal reports;
- Develop and mentor less experienced staff;
- Keep up to date with the latest scientific advances and trends in drug discovery to deliver the next-generation therapies;
- Undertake ongoing professional development by attending relevant training and conferences.
Qualifications
- MSc/PhD in a relevant scientific discipline (Pharmaceutical Sciences, Chemistry, Computational Chemistry) with a solid foundation in molecular modelling built in a pharma/biotech/CRO setting;
- Expert knowledge in CADD software packages and modern molecular modelling techniques;
- Sound knowledge in cutting-edge cheminformatic tools, AI/ML-enabled technologies, and in silico drug design, including both structure- and ligand-based methodologies;
- Passion for drug discovery with a deep entrepreneurial and problem-solving attitude;
- Mastery of all the theoretical and practical principles of medicinal chemistry and drug design;
- Broad knowledge of biophysical, biochemical, and cell-based assays used in the early stages of the drug discovery process;
- In depth understanding of multi-parameter optimization and ability to integrate disease biology, ADME/DMPK and toxicology data to solve complex drug discovery problems;
- Excellent leadership, management, organizational and team-working skills, and a talent to deliver project milestones within the expected time frame;
- Demonstrated track record of scientific publications;
- Exceptional oral, written, and interpersonal communication skills, and ability to develop and grow strong cross-functional collaborations.
Senior Principal Scientist, Computational Chemist Jazz Pharmaceuticals Cambridge or Sittingbour[...] in Sittingbourne employer: Jazz Pharmaceuticals, Inc.
Contact Detail:
Jazz Pharmaceuticals, Inc. Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Principal Scientist, Computational Chemist Jazz Pharmaceuticals Cambridge or Sittingbour[...] in Sittingbourne
✨Tip Number 1
Network like a pro! Reach out to professionals in the field through LinkedIn or industry events. A friendly chat can lead to opportunities that aren’t even advertised yet.
✨Tip Number 2
Show off your skills! Prepare a portfolio of your past projects and achievements. When you get the chance, share how your expertise in computational chemistry can drive innovation at Jazz Pharmaceuticals.
✨Tip Number 3
Practice makes perfect! Get ready for interviews by rehearsing common questions and scenarios related to drug discovery. We want you to feel confident showcasing your leadership and problem-solving skills.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets noticed. Plus, it shows you’re genuinely interested in joining our team at Jazz Pharmaceuticals.
We think you need these skills to ace Senior Principal Scientist, Computational Chemist Jazz Pharmaceuticals Cambridge or Sittingbour[...] in Sittingbourne
Some tips for your application 🫡
Tailor Your CV: Make sure your CV reflects the skills and experiences that align with the Senior Principal Scientist role. Highlight your expertise in computational chemistry and any relevant projects you've led or contributed to.
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to tell us why you're passionate about drug discovery and how your background makes you a perfect fit for our team. Be sure to mention specific experiences that relate to the job description.
Showcase Your Collaborative Spirit: Since collaboration is key in our multi-disciplinary environment, share examples of how you've worked effectively with other scientists or departments. This will show us that you can thrive in our dynamic setting.
Apply Through Our Website: We encourage you to apply directly through our website. It’s the best way to ensure your application gets into the right hands and shows us you're serious about joining our innovative team at Jazz Pharmaceuticals.
How to prepare for a job interview at Jazz Pharmaceuticals, Inc.
✨Know Your Science
Make sure you brush up on the latest advancements in computational chemistry and drug discovery. Be prepared to discuss specific methodologies you've used, especially in molecular modelling and cheminformatics. This shows your passion and expertise in the field.
✨Showcase Your Collaboration Skills
Since the role involves working with multi-disciplinary teams, think of examples where you've successfully collaborated with others. Highlight how you’ve contributed to projects across different functions, as this will demonstrate your ability to work effectively within Jazz Pharmaceuticals' environment.
✨Prepare for Leadership Questions
As a Senior Principal Scientist, you'll be expected to lead projects and mentor others. Prepare to discuss your leadership style and provide examples of how you've guided teams or driven projects to success. This will help convey your readiness for the responsibilities of the role.
✨Communicate Clearly and Confidently
Practice articulating your thoughts clearly, especially when discussing complex scientific concepts. You might be asked to present your ideas or results, so being able to communicate effectively is key. Remember, confidence can make a big difference in how your expertise is perceived.
