Senior Director, Global Medical Director, Neuro-Oncology

The Senior Director, Global Medical Director, Neuro-Oncology will be the Medical Affairs lead for the Neuro-Oncology disease area, including in line and early assets. This role is a key member of Global Commercialization Organization Medical Affairs (GCOMA) Oncology and reports to the VP, Global Medical Franchise Lead, Oncology, Medical Affairs. This is a new, hybrid role with dual responsibility for US and Global strategy and execution.

This role will lead the US Neuro-Oncology Medical Affairs team, partnering closely with global development, EU/International and US cross-functional partners to create and deliver on medical affairs strategy and input operating with the US as the principal region approach. This is a strategic role with both people management and execution responsibilities and is accountable for ensuring the needs and priorities of the regions are represented and addressed through engagement with key partners across Jazz.

The Senior Director, Global Medical Director ensures a deep understanding of customer, patient, and healthcare system needs are represented consistently across cross-functional discussions and decision-making forums. This role will provide strategic leadership and contributions directly or through team members in support of the clinical development team to determine and align on future treatment landscape scenarios for assets in early development through commercialization for all Neuro-Oncology assets.

The Senior Medical Director will inform and influence clinical development strategy, evidence plans and the target product profile for such products, with a bias toward the United States therapeutic landscape as the driver of strategic planning. The role serves as a critical interface between Medical Affairs and global R&D, Early/Clinical Development, Global Product Development and Commercialization functions, to ensure regional insights and priorities are understood, communicated, and appropriately considered within the Global Product Team (GPT), Commercial Development Team (CDT), Medical Functional Matrix Team (FMT), and governance forums including the Portfolio Governance Committee (PGC) and Development Project Review Committee (DPRC).

This role leads the US medical affairs team with responsibility to deliver strategy and execution in support of the US indications in Neuro-Oncology in alignment with Neuro-Oncology commercial leadership and partners in the US market.

Essential Functions/Responsibilities:

• Lead the global and US Medical Affairs Neuro-Oncology team to deliver all aspects of medical affairs strategy in support of pipeline and marketed products.
• Lead the global medical Neuro-Oncology FMT.
• Provide strategic and executional leadership and guidance to team members to deliver US medical plan in support of all indications and launch planning.
• Lead and develop team members in high performing team culture.
• Lead the development, maintenance, and execution of the Integrated Evidence Generation Plan Neuro-Oncology including investigator-sponsored studies, real-world evidence initiatives, health outcomes research, and Phase IV interventional studies, where appropriate.
• Responsible for the development of the scientific narrative for Neuro-Oncology indications by identifying and advancing key analytic needs and informing the interpretation of pivotal trial data.
• Represent and advocate for medical perspectives within global cross-functional teams and governance forums, including GPT, CDT, PGC, and DPRC.
• Contribute Medical Affairs expertise to inform early development activities for early pipeline assets, including Target Product Profile (TPP) development, clinical trial design and lifecycle planning based on regional insights and aligned future therapeutic landscape scenarios.
• Ensure regional needs and insights are appropriately considered in early/clinical development discussions, evidence-generation activities, and lifecycle planning.
• Maintain and apply a deep understanding of the competitive landscape to inform evidence generation strategy and internal development decisions.
• Partner effectively across Medical Affairs, Clinical Development, Regulatory Affairs, Market Access, HEOR, RWE, Commercial, and other cross-functional teams to support evidence generation and scientific exchange.
• Lead development and execution of publication strategy and publication plans in alignment with regional evidence needs and scientific priorities.
• Support scientific communications, congress planning, advisory boards, and external engagement activities as required.

Required Knowledge, Skills, and Abilities:

• A minimum of 10 years of Medical Affairs, Clinical Development, or related pharmaceutical or biotechnology industry experience is required.
• A minimum of 5 years of experience leading US strategy and in-line execution is required.
• Experience in people management strongly preferred.
• Experience in Neuro-Oncology is strongly preferred.
• Demonstrated experience developing and executing evidence-generation strategies, publication plans, and external scientific engagement activities.
• Strong understanding of clinical research, evidence generation, and drug development.
• Proven ability to influence without authority and operate effectively within complex matrix organizations.
• Strong strategic thinking coupled with excellent operational execution skills.
• Excellent written, verbal, presentation, and stakeholder management skills.
• Ability to build productive partnerships across regions and functions and effectively represent diverse stakeholder perspectives.
• Demonstrated ability to manage multiple priorities and deliver high-quality outcomes in a fast-paced environment.
• Evidence of success in matrix organizations and track record of high performing behaviors, including independent critical thinking, initiative, and execution under time pressure with competing priorities.
• Self-awareness and emotional intelligence as demonstrated by prior experience navigating complex matrix environments successfully.

Required/Preferred Education and Licenses:

• Advanced scientific or healthcare degree required (PharmD, PhD, MD, MBBS, Nurse Practitioner, PA, or equivalent).
• Experience in the delivery of oncology care preferred.