Director, Neuroscience Medical Affairs

IXICO plc (AIM: IXI) is a global leader in neuroscience imaging and biomarker analytics, using its proprietary AI‑driven platform to help advance the treatment of neurological disorders and reduce the uncertainties associated with drug discovery, development and monitoring. As a key part of the global neurological disease research community, the Company has built a global reputation and 20‑year track record as an end‑to‑end Imaging Contract Research Organisation (iCRO) working with leading pharma companies, innovative biotech's, disease consortia and non‑profit organisations. IXICO has supported hundreds of neurological clinical trials, analysed hundreds of thousands scans and built an expansive network of expert imaging centres around the world.

The IXICO Platform is tailor‑made for neurological disease, reliably processing data from global trials, precisely measuring key imaging biomarkers associated with the identification, progression and treatment of diseases such as Alzheimer’s, Huntington’s and Parkinson’s. Image data is interrogated by the Platform and IXICO’s expert scientists translating complex data into clinically meaningful insights while minimizing data variability and increasing reproducibility.

Our people are empowered to enable us to achieve our company goals and their own personal development through the “4A” values at the heart of our culture: Aspiration, Ability, Agility and Accountability.

To help us deliver our medical image analysis solutions to large clinical trials we are hiring a dedicated Director, Neuroscience Medical Affairs on a permanent full‑time capacity.

Purpose of the Role: The Director, Neuroscience Medical Affairs is a senior medical‑scientific lead, reporting directly to the CSO/CMO. The role holder leads priority Key Opinion Leader (KOL) relationships, provides senior scientific input to pharma engagements and partnerships, drives the company’s publication and congress activity, and contributes medical input to IXICO’s growing portfolio of regulated software products. The role spans IXICO’s full therapeutic‑area scope (AD, PD, HD and selected rare neurological indications) and reflects the company’s evolving scientific positioning, including the increasing relevance of multimodal biomarker integration as the diagnostic and treatment landscape evolves. The role is hands‑on and externally visible: the post holder is expected to be a credible scientific voice for IXICO with pharma sponsors, KOLs, consortia and clinical networks.

Essential Duties and Responsibilities:

• Medical Affairs strategy and planning: Working closely with the CSO/CMO, support development of the Medical Affairs strategy and lead translation into an actionable annual operating plan covering KOL engagement, publications, congresses, consortium activity and pharma scientific engagement. Own end‑to‑end delivery of priority workstreams against this plan, with clear KPIs and reporting cadence. Identify and surface emerging scientific and competitive developments that may inform updates to the strategy, including evolutions in the diagnostic frameworks, the multimodal biomarker landscape, treatment mechanisms, and the regulated software product space.
• KOL and clinical‑network engagement: Lead day‑to‑day engagement with priority KOLs across AD, PD, HD and selected rare neurological indications. Maintain and grow relationships with consortium partners and Scientific Advisory Board members. Build relationships into neurologist, memory‑clinic and diagnostic‑imaging‑network communities to understand evolving requirements for clinical decision‑support tools.
• Publications, congresses and external scientific communication: Drive IXICO’s peer‑reviewed publication output across priority scientific themes. Support planning of IXICO’s scientific congress presence at major meetings, including abstract submissions, presentations, KOL meetings and pharma engagement. Support development and review of external scientific material (e.g. webinars, white papers, blog posts, website content), assuring scientific accuracy and alignment with the agreed commercial and scientific positioning.
• Pharma sponsor and partner medical engagement: Provide medical support to Business Development, including bid defences, capability presentations and scientific advisory interactions with pharma sponsors. Act as a scientific point of contact in strategic partnerships, supporting joint scientific narratives, co‑publications and co‑developed evidence packages where appropriate. Provide medical input into proposals, statements of work and study imaging charters where senior medical‑affairs perspective is needed.
• Medical input to products and regulatory submissions: Contribute medical and clinical‑scientific input to IXICO’s SaMD and analytics product roadmap, including intended‑use definition, claim‑specific validation considerations and the clinical‑evidence narrative for products. Partner with Regulatory Affairs and R&D teams to ensure compliance and scientific integrity.