Synthetic Chemistry Lead, London, Lausanne

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life‐changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery. Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.

Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel‐winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed. Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI's powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world's most devastating diseases.

Our dynamic team of Synthetic Chemists and CRO Leads are dedicated to transforming drug design and manufacturing. We work in partnership with our AI/ML and drug discovery colleagues to support all phases of chemistry, from early to late stages, as well as managing our extensive external CRO team. We promote a supportive atmosphere where the diverse expertise of every team member is recognised and appreciated. We maintain a strong growth mindset, with continuous development and learning as a priority.

If you are a skilled and ambitious scientist looking to take the next step in your career, joining Isomorphic Labs will lift you out of your comfort zone and provide you with an amazing opportunity for personal growth and development.

Your impact:

• Apply your Synthetic Chemistry expertise across Medicinal Chemistry and/or CMC projects.
• Act as a Synthetic Chemistry Lead in one or more active drug discovery programs.
• Collaborate both internally and with third‐party organisations, interacting within multidisciplinary teams to support the data‐driven delivery of high quality scientific solutions to complex technical problems.
• Work cross‐functionally with the Medicinal Chemistry, DMPK, Biology, and Technology teams.
• Represent the company externally, interacting with existing and prospective collaborators including Contract Research Organisations (CROs) and Contract Development & Manufacturing Organisations (CDMOs).
• Prepare detailed scientific proposals and reports to support new and ongoing programs.
• Embrace and champion our culture of inclusion and continuous professional development.

Skills And Qualifications:

• PhD in Synthetic Chemistry, or a related technical field, or equivalent industrial experience.
• 3+ years' professional experience in a Chemistry role, operating within a biotech, pharma or CRO setting. 5+ years' experience for more senior positions.
• Solid technical foundation in synthetic chemistry with previous experience operating independently as an individual contributor.
• Excellent problem‐solving and decision‐making capabilities applied to complex synthetic chemistry challenges.
• Experience of working with and closely managing CRO and/or CDMO resources.
• A genuine passion for drug discovery and enthusiasm for the potential of AI/ML to transform the field.
• Excellent communication (written and verbal) and interpersonal skills, with an ability to work effectively in a cross‐functional, collaborative team environment.
• Track record of creative problem solving with a strong growth mindset, adaptability, and eagerness to learn new concepts and techniques.

Culture and values:

• Thoughtful – Curious, creative and caring. It is about good people doing good, rigorous and future‐making science every single day.
• Brave – Fearlessness, but also initiative and integrity. The scale of the challenge demands nothing less.
• Determined – Confidence in our hypothesis, urgency and agility needed to deliver.
• Together – Connection, collaboration across fields and catalytic relationships. Transformation is a group project, impacting real people worldwide.
• Creating An Extraordinary Company – We believe that to be successful we need a team with a range of skills and talents. We build an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive.

Hybrid working:

It's hugely important for us to share knowledge and build strong relationships with each other, so we follow a hybrid model. You would be required to come into the office 3 days a week (currently Tuesday, Wednesday and one other day depending on which team you're in). If you have additional needs that would prevent you from following this hybrid approach, we'd be happy to talk through these if you're selected for an initial screening call.

We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know.