At a Glance
- Tasks: Use AI to solve drug design problems and mentor junior colleagues.
- Company: Isomorphic Labs, a pioneering tech company in drug discovery.
- Benefits: Hybrid work model, inclusive culture, and opportunities for professional growth.
- Other info: Collaborative environment that values diverse perspectives and continuous learning.
- Why this job: Join a mission to revolutionise healthcare with cutting-edge AI technology.
- Qualifications: PhD in relevant field and 5+ years of industry experience required.
The predicted salary is between 70000 - 90000 € per year.
Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. We aim to accelerate drug discovery through AI, transforming the way diseases are addressed from earlier stages to cure.
About Iso
Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. We combine drug discovery expertise with machine learning to develop predictive and generative AI models that accelerate scientific discovery at digital speed.
Your impact
You will play an integral role in our drug discovery project teams, applying modern drug design principles to provide strategic input and advance our programs. You will use AI in computational drug design, gaining hands‑on experience with state-of-the-art computational tools in real‑world challenges. You will contribute scientific expertise and strategic direction to improve our platform.
What you will do
- Apply your expertise in computational drug design to solve drug design problems and provide technical direction to our Platform teams.
- Collaborate internally and with third‑party organisations to support the data‑driven delivery of high quality designs, and solutions to complex technical problems.
- Prepare detailed scientific proposals and reports to support new and ongoing drug discovery programs.
- Mentor and support the development of more junior colleagues in our growing team.
- Embrace and champion our culture of inclusion and continuous professional development.
Skills and qualifications
- PhD in Computational Chemistry, Medicinal Chemistry, Synthetic Organic Chemistry (or related technical field), or equivalent industrial experience.
- 5+ years industrial experience in computational chemistry (CADD) within biotech or pharma setting.
- Strong foundational knowledge of modern computational chemistry, including cheminformatics, virtual screening, docking, machine learning models, model assessment.
- Experience contributing to structure‑based drug design (SBDD) problems, with a proven track record of success.
- Experience writing and implementing Python scripts, or utilising pipelining tools, to support project teams in cheminformatic and computational chemistry design workflows.
- Passion and enthusiasm for applying AI/ML to drug design.
- Excellent communication and interpersonal skills, ability to work effectively in cross‑functional teams.
- Strong growth mindset, adaptability, eagerness to learn new concepts and techniques.
Nice to have
- Experience working with or managing activities at contract research organisations (CROs).
- Familiarity with medicinal chemistry techniques (data analysis software, ADMET principles).
- Knowledge of fragment‑based drug design (FBDD), and alternative modalities like PROTACs, molecular glues, PPI inhibitors or stabilisers.
- Basic understanding of drug metabolism and pharmacokinetics (DMPK) principles.
- Fluency in Python with ability to write code for new tools.
- Track record of authorship of relevant scientific manuscripts and/or inventorship of composition of matter patents.
Culture and values
Our shared values guide our work: thoughtful, brave, determined, and together. We encourage curiosity, creativity and care; fearlessness, initiative and integrity; confidence in our hypotheses and urgency to deliver; and connection, collaboration and catalytic relationships.
Creating an extraordinary company
We build an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds and perspectives to create extraordinary impact.
We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please let us know.
We follow a hybrid model requiring employees to be in the office 3 days a week (currently Tuesday, Wednesday, and one other day). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call.
Computational Drug Designer, London, Lausanne Lausanne; London employer: Isomorphic Labs Limited
Isomorphic Labs is an exceptional employer, fostering a culture of collaboration and continuous professional development in the heart of London and Lausanne. With a commitment to advancing human health through innovative AI-driven drug discovery, employees benefit from hands-on experience with cutting-edge technology, mentorship opportunities, and a supportive environment that values diverse perspectives. Join us to make a meaningful impact in the fight against disease while enjoying a flexible hybrid work model that promotes work-life balance.
StudySmarter Expert Advice🤫
We think this is how you could land Computational Drug Designer, London, Lausanne Lausanne; London
✨Tip Number 1
Network like a pro! Reach out to people in the industry, attend events, and connect with professionals on LinkedIn. You never know who might have the inside scoop on job openings or can refer you directly.
✨Tip Number 2
Show off your skills! Create a portfolio or GitHub repository showcasing your projects and coding skills in Python. This is a great way to demonstrate your expertise in computational drug design and make a lasting impression.
✨Tip Number 3
Prepare for interviews by brushing up on your technical knowledge and soft skills. Practice common interview questions related to computational chemistry and be ready to discuss your past experiences and how they relate to the role.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, it shows you’re genuinely interested in joining our team at Isomorphic Labs.
We think you need these skills to ace Computational Drug Designer, London, Lausanne Lausanne; London
Some tips for your application 🫡
Show Your Passion:When you're writing your application, let your enthusiasm for computational drug design and AI shine through. We want to see that you’re not just qualified, but genuinely excited about the work we do at Isomorphic Labs!
Tailor Your Application:Make sure to customise your CV and cover letter to highlight your relevant experience in computational chemistry and drug design. We love seeing how your unique background aligns with our mission, so don’t hold back!
Be Clear and Concise:Keep your written application straightforward and to the point. Use clear language to describe your skills and experiences, as this helps us quickly understand how you can contribute to our team.
Apply Through Our Website:We encourage you to submit your application directly through our website. It’s the best way to ensure it gets into the right hands and shows us you’re serious about joining our team!
How to prepare for a job interview at Isomorphic Labs Limited
✨Know Your Stuff
Make sure you brush up on your computational drug design knowledge. Familiarise yourself with the latest AI and machine learning techniques relevant to drug discovery. Be ready to discuss specific projects you've worked on and how they relate to the role.
✨Show Your Collaborative Spirit
Isomorphic Labs values teamwork, so be prepared to share examples of how you've successfully collaborated with others in cross-functional teams. Highlight any mentoring experiences you have, as this shows your commitment to supporting junior colleagues.
✨Prepare for Technical Questions
Expect to face technical questions related to cheminformatics, virtual screening, and structure-based drug design. Brush up on your Python skills too, as you might be asked about coding or implementing scripts during the interview.
✨Embrace Their Culture
Familiarise yourself with Isomorphic Labs' values: thoughtful, brave, determined, and together. Think of examples from your past that demonstrate these qualities, and be ready to discuss how you can contribute to their culture of inclusion and continuous professional development.
