b Overview /b p As Principal Scientist, you will lead Cell Line Development and Upstream Process Development for biologics, guiding projects from early stage to commercial manufacture. You will provide scientific leadership across CLD and USP, mentoring junior scientists and ensuring robust, scalable processes. You’ll collaborate with cross-functional teams and external CDMOs to drive programme delivery and technology transfer. This role offers exposure to a diverse biologics pipeline and a chance to shape development strategy within a global biopharma network. You’ll work in a collaborative, innovation-driven culture focused on impactful patient outcomes and continuous improvement. /p b Pay / Benefits /b ul li Flexible hybrid working /li li International collaboration across UK, Ireland and France /li li Exposure to diverse biologics pipeline /li li Culture of scientific excellence and continuous learning /li li Mentoring opportunities and career development /li li Global biopharmaceutical environment /li /ul b Responsibilities /b ul li Lead CLD and Upstream Process Development strategies across biologics development programs /li li Provide scientific leadership for CMC development projects from early development through commercialisation /li li Act as subject matter expert for CLD and USP activities to support technical decision-making /li li Drive innovation and continuous improvement to enhance process productivity, robustness and product quality /li li Represent Upstream Process Development within multidisciplinary CMC teams /li li Collaborate with internal stakeholders and external CMOs for development, scale-up and technology transfer /li li Contribute to regulatory submissions and technical documentation /li li Conduct technical assessments for new product opportunities and in-licensing /li li Mentor, coach and develop junior scientists /li /ul b Key requirements /b ul li Significant pharmaceutical or biotechnology industry experience within biologics development /li li Deep expertise in Cell Line Development and/or Upstream Process Development /li li Strong experience with CHO cell lines and mammalian cell culture processes /li li Experience leading CMC development activities across the product lifecycle /li li Proven ability to work with cross-functional stakeholders and external partners /li li Experience engaging with and managing activities CDMOs /li li Strong communication, influencing and stakeholder management skills /li /ul ul li leadership /li li communication /li li influence /li li Cell Line Development /li li Upstream Process Development /li li CHO cell culture /li /ul
Principal Scientist employer: Ipsen
Ipsen Biopharm Ltd is an exceptional employer that prioritises a human-centric workplace culture, fostering collaboration and excellence. With a commitment to employee growth, Ipsen offers opportunities for continuous improvement and innovation in the biopharmaceutical field, particularly in vibrant locations like Paris and London. Employees are empowered to thrive, making a meaningful impact on patients and society while enjoying a supportive environment that values diverse perspectives.
