At a Glance
- Tasks: Discover and develop inhibitors for cancer treatment using innovative structural biology techniques.
- Company: University of Oxford, a leading institution in molecular medicine.
- Benefits: Three-year funded position with opportunities for professional growth and research impact.
- Other info: Collaborative environment focused on equality and diversity.
- Why this job: Join a groundbreaking project that aims to revolutionise cancer treatment through drug discovery.
- Qualifications: PhD in structural biology and experience in protein production and analysis.
The predicted salary is between 35000 - 45000 £ per year.
Applications are invited for a postdoctoral position to discover and develop inhibitors of oncogenic proteins for cancer treatment. The post is available for 3 years, funded by the Medical Research Council.
The aim of the work is to discover small-molecule drugs that inhibit protein-protein interactions involving transcription factor multi-protein complexes. The approach will involve novel strategies using single domain antibody fragments and peptides as tools for the identification of drug-like molecules for hit to lead development and assay development for characterization and target validation.
The programme involves structural determination of protein complexes together with screening and characterization of small molecule inhibitors of protein-protein interactions. In particular, the project will use the structure of single antibody domains as templates for drug lead development.
Candidates must have a PhD in structural biology, experience with recombinant protein production purification, with solving structures using X-ray diffraction and analyzing protein interactions using biophysical techniques. Experience with mammalian and yeast culture would be an advantage.
Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.
The closing date for this position is noon on Thursday 21 November 2013.
Committed to equality and valuing diversity.
Postdoctoral Scientist: Structural Biology & Drug Discovery in Oxford employer: Instruct-ERIC
The University of Oxford is an exceptional employer, offering a vibrant and collaborative work culture that fosters innovation and academic excellence. As a Postdoctoral Research Assistant in Structural Biology, you will have access to cutting-edge facilities and resources, alongside opportunities for professional development and networking within a world-renowned institution. Located in the historic city of Oxford, you will enjoy a stimulating environment that encourages both personal and professional growth while contributing to groundbreaking research in bacterial membrane biology.
StudySmarter Expert Advice🤫
We think this is how you could land Postdoctoral Scientist: Structural Biology & Drug Discovery in Oxford
✨Get Involved in Local Research Communities
Tap into local biotechnology meetups and research forums. These are great places to mingle with industry professionals, share your passion, and even discover unadvertised job openings. It's all about getting your face known in the field!
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Curate a portfolio showcasing any research projects or internships you've completed in biotechnology. This tangible evidence of your skills can really impress employers when you chat with them at networking events or interviews. It's about making that killer first impression!
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Biotech is a fast-paced field, so keeping yourself updated with the latest advancements is crucial. Attend industry conferences, webinars, or workshops to broaden your knowledge and meet potential employers. Plus, it’ll give you fantastic talking points for your interviews at places like Instruct-ERIC!
We think you need these skills to ace Postdoctoral Scientist: Structural Biology & Drug Discovery in Oxford
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show Instruct-ERIC that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at Instruct-ERIC.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that Instruct-ERIC does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at Instruct-ERIC
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at Instruct-ERIC. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
✨Show Your Teamwork Skills
Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into Instruct-ERIC's culture.
✨Research Recent Biotech Innovations
Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at Instruct-ERIC. This shows your passion for the industry!
