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- Tasks: Lead cutting-edge analyses to identify new drug targets for cardiometabolic diseases.
- Company: Major European pharmaceutical client with a focus on R&D and AI.
- Benefits: Permanent position in vibrant locations, competitive salary, and opportunities for professional growth.
- Why this job: Make a real impact on drug discovery using advanced AI and data analysis.
- Qualifications: Master’s or PhD in biology, extensive pharma experience, and strong leadership skills.
- Other info: Collaborative environment with a focus on innovative drug target identification.
The predicted salary is between 72000 - 108000 ÂŁ per year.
Insight Global are seeking a Senior Principal Scientist on behalf of a major European pharmaceutical client of ours, within their R&D AI team. This role is a permanent position, based in either Central London or Oxford.
As Senior Principal Scientist, you will perform cutting edge analyses of cellular phenotype data derived from ultra-high throughput genetic and compound screens to identify new drug targets for cardiometabolic disease. You will have direct impact on our early pipeline and lead the scientific deliveries from our flagship genome-scale in‑vitro perturbation screens producing high‑content imaging and functional genomics data and help us translate these into compelling drug projects.
Responsibilities Include:
- Scientific leadership and execution of high-value AI and data analysis projects for target discovery.
- Translation of ultra-high throughput in‑vitro screening analysis results/insights into drug target candidates and pipeline projects.
- Systems biology‑guided interrogation of high‑dimensional cell‑painting embeddings & omics (incl. DRUG‑seq/perturb‑seq) data derived from genetic & chemical perturbations.
- Keep pace with cutting edge biology‑focused AI methods and contribute to the development of internal evaluations/benchmarks to keep our models focused on value to our discovery pipeline.
- Develop collaborative and strategic relationships with key stakeholders in our therapy areas to ensure alignment with the global drug discovery strategy and portfolio.
Must-Have Requirements Include:
- Master’s degree or a PhD in cellular/molecular/computational biology.
- Extensive experience in a pharma/tech bio context.
- Scientific leadership experience in cross‑functional teams with a track record of progressing novel biological hypotheses, ideally focused on drug target identification within a pharma industry context.
- Experience applying cutting edge AI and systems biology methods to generate, analyse and interpret high‑dimensional datasets, preferably from HCI/omics data on in‑vitro genetic/compound screens.
- Independence and motivation to perform in‑depth biology‑focused data analysis and work with project and leadership teams to progress targets.
- Experience working in Python/R to curate and analyse data.
- Experience in CMD‑relevant cellular/molecular biology is an advantage.
Senior Principal Scientist in Oxford employer: Insight Global
Contact Detail:
Insight Global Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Principal Scientist in Oxford
✨Tip Number 1
Network like a pro! Reach out to your connections in the pharma and AI sectors. We all know that sometimes it’s not just what you know, but who you know. Attend industry events or webinars to meet potential colleagues and get your name out there.
✨Tip Number 2
Show off your skills! Prepare a portfolio of your past projects, especially those involving high-dimensional datasets or AI methods. We want to see how you’ve tackled challenges in drug target identification and how you can bring that expertise to our team.
✨Tip Number 3
Practice makes perfect! Get ready for interviews by rehearsing answers to common questions in the pharma and AI fields. We suggest focusing on your scientific leadership experiences and how you’ve driven projects forward in cross-functional teams.
✨Tip Number 4
Apply through our website! It’s the best way to ensure your application gets seen by the right people. We’re excited to find someone who can lead our R&D AI team, so don’t hesitate to showcase your passion for drug discovery and innovation.
We think you need these skills to ace Senior Principal Scientist in Oxford
Some tips for your application 🫡
Tailor Your CV: Make sure your CV reflects the skills and experiences that match the Senior Principal Scientist role. Highlight your expertise in cellular/molecular biology and any relevant AI methods you've used. We want to see how you can contribute to our R&D AI team!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about drug discovery and how your background aligns with our mission at StudySmarter. Be sure to mention specific projects or experiences that showcase your scientific leadership.
Showcase Your Technical Skills: Since this role involves data analysis, make sure to highlight your proficiency in Python/R and any experience with high-dimensional datasets. We love seeing candidates who can demonstrate their technical prowess and how it applies to our work in drug target identification.
Apply Through Our Website: We encourage you to apply directly through our website for the best chance of getting noticed. It’s the easiest way for us to keep track of your application and ensure it reaches the right people. Don’t miss out on this opportunity!
How to prepare for a job interview at Insight Global
✨Know Your Science
Make sure you brush up on the latest trends in cellular and molecular biology, especially those related to drug target identification. Be ready to discuss your previous experiences with high-dimensional datasets and how you've applied AI methods in your work.
✨Showcase Your Leadership Skills
As a Senior Principal Scientist, you'll need to demonstrate your ability to lead cross-functional teams. Prepare examples of how you've successfully guided projects or influenced stakeholders in your past roles, highlighting your scientific leadership.
✨Familiarise Yourself with the Company’s Pipeline
Research the pharmaceutical client’s current drug discovery projects and their R&D AI initiatives. This will not only show your interest but also help you align your skills and experiences with their goals during the interview.
✨Prepare for Technical Questions
Expect to dive deep into technical discussions about data analysis using Python or R. Brush up on your coding skills and be prepared to explain your thought process when analysing complex datasets, as this will be crucial for the role.
