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- Tasks: Lead cutting-edge analyses to identify new drug targets for cardiometabolic diseases.
- Company: Major European pharmaceutical client with a focus on R&D and AI.
- Benefits: Permanent position in vibrant locations, competitive salary, and opportunities for professional growth.
- Why this job: Make a real impact on drug discovery using advanced AI and data analysis.
- Qualifications: Master’s or PhD in relevant fields with extensive pharma/tech experience.
- Other info: Collaborative environment with a focus on innovative drug target identification.
The predicted salary is between 72000 - 108000 ÂŁ per year.
Insight Global are seeking a Senior Principal Scientist on behalf of a major European pharmaceutical client of ours, within their R&D AI team. This role is a permanent position, based in either Central London or Oxford.
As Senior Principal Scientist, you will perform cutting edge analyses of cellular phenotype data derived from ultra-high throughput genetic and compound screens to identify new drug targets for cardiometabolic disease. You will have direct impact on our early pipeline and lead the scientific deliveries from our flagship genome-scale in‑vitro perturbation screens producing high‑content imaging and functional genomics data and help us translate these into compelling drug projects.
Responsibilities Include:
- Scientific leadership and execution of high-value AI and data analysis projects for target discovery.
- Translation of ultra-high throughput in‑vitro screening analysis results/insights into drug target candidates and pipeline projects.
- Systems biology‑guided interrogation of high‑dimensional cell‑painting embeddings & omics (incl. DRUG‑seq/perturb‑seq) data derived from genetic & chemical perturbations.
- Keep pace with cutting edge biology‑focused AI methods and contribute to the development of internal evaluations/benchmarks to keep our models focused on value to our discovery pipeline.
- Develop collaborative and strategic relationships with key stakeholders in our therapy areas to ensure alignment with the global drug discovery strategy and portfolio.
Must-Have Requirements Include:
- Master’s degree or a PhD in cellular/molecular/computational biology.
- Extensive experience in a pharma/tech bio context.
- Scientific leadership experience in cross‑functional teams with a track record of progressing novel biological hypotheses, ideally focused on drug target identification within a pharma industry context.
- Experience applying cutting edge AI and systems biology methods to generate, analyse and interpret high‑dimensional datasets, preferably from HCI/omics data on in‑vitro genetic/compound screens.
- Independence and motivation to perform in‑depth biology‑focused data analysis and work with project and leadership teams to progress targets.
- Experience working in Python/R to curate and analyse data.
- Experience in CMD‑relevant cellular/molecular biology is an advantage.
Senior Principal Scientist in London employer: Insight Global
Contact Detail:
Insight Global Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Principal Scientist in London
✨Tip Number 1
Network like a pro! Reach out to your connections in the pharma and AI sectors. Attend industry events or webinars, and don’t be shy about introducing yourself. You never know who might have the inside scoop on job openings!
✨Tip Number 2
Show off your expertise! Prepare a portfolio or presentation that highlights your previous projects, especially those involving high-dimensional datasets and AI methods. This will help you stand out during interviews and showcase your scientific leadership.
✨Tip Number 3
Practice makes perfect! Conduct mock interviews with friends or mentors in the field. Focus on articulating your experience with drug target identification and systems biology methods. The more comfortable you are discussing your work, the better you'll perform.
✨Tip Number 4
Apply through our website! We’ve got a streamlined application process that makes it easy for you to get your foot in the door. Plus, it shows you’re genuinely interested in joining our team and contributing to cutting-edge research.
We think you need these skills to ace Senior Principal Scientist in London
Some tips for your application 🫡
Tailor Your CV: Make sure your CV reflects the skills and experiences that match the Senior Principal Scientist role. Highlight your expertise in cellular/molecular biology and any relevant AI methods you've used. We want to see how you can contribute to our R&D AI team!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about drug discovery and how your background aligns with our mission at StudySmarter. Be sure to mention specific projects or experiences that showcase your scientific leadership.
Showcase Your Technical Skills: Since this role involves data analysis, make sure to highlight your proficiency in Python or R. Include examples of how you've used these tools to analyse high-dimensional datasets, especially in a pharma context. We love seeing practical applications of your skills!
Apply Through Our Website: We encourage you to apply directly through our website for the best chance of getting noticed. It’s the easiest way for us to keep track of your application and ensure it reaches the right people. Don’t miss out on this opportunity!
How to prepare for a job interview at Insight Global
✨Know Your Science
Make sure you brush up on the latest trends in cellular and molecular biology, especially those related to drug target identification. Be ready to discuss your previous projects and how they relate to the role, showcasing your scientific leadership and experience in cross-functional teams.
✨Showcase Your AI Skills
Since this role involves cutting-edge AI methods, be prepared to talk about your experience with Python or R. Highlight specific projects where you've applied these skills to analyse high-dimensional datasets, particularly in a pharma context. This will demonstrate your technical prowess and relevance to the position.
✨Prepare for Scenario Questions
Expect questions that assess your problem-solving abilities and how you handle challenges in a collaborative environment. Think of examples where you've led a project or navigated complex data analysis, and be ready to explain your thought process and outcomes.
✨Align with Their Vision
Research the company’s drug discovery strategy and be ready to discuss how your background aligns with their goals. Showing that you understand their pipeline and can contribute to their mission will set you apart as a candidate who is genuinely interested in the role.
