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- Tasks: Join a vibrant team to discover and develop cyclic peptides for therapeutic targets.
- Company: Imperial College London, a world-leading institution in chemical biology.
- Benefits: Sector-leading salary, flexible working, generous family leave, and travel schemes.
- Why this job: Make a real impact in science while working on innovative peptide discovery projects.
- Qualifications: Experience in peptide chemistry and a passion for multidisciplinary research.
- Other info: Collaborative culture with opportunities for career growth and personal development.
The predicted salary is between 36000 - 60000 £ per year.
Seeking a researcher in chemical biology to contribute to our team’s efforts to discover and develop cyclic peptides to a range of therapeutically relevant protein targets using mRNA display. You will work based at the Molecular Sciences Research Hub within the Chemistry Department at Imperial College London. The Walport lab is a highly interdisciplinary lab that uses a wide variety of techniques, spanning from synthetic and peptide chemistry to cell biology, to study biomedically important proteins.
This position is part of a collaborative research programme between Imperial College London and the Laboratory for Synthetic Chemistry and Chemical Biology Limited (LSCCB) in Hong Kong, bringing together complementary expertise in peptide chemistry, chemical biology, and therapeutic development. There may be an opportunity to pursue some work in the LSCCB laboratories in Hong Kong.
Building on our recent development of lysate-based mRNA display, you will join a vibrant research group to extend this screening methodology. You will develop cyclic peptide inhibitors of a range of difficult-to-drug, therapeutically relevant protein targets. You will carry out novel research adapting and applying our mRNA-display-based peptide discovery protocols. Your work will involve mammalian cell culture to produce screening cell lines, performing RaPID screens against cell-lysate based targets, hit validation, optimising your peptides for cellular delivery, and applying these tools in a range of structural, biochemical and cellular assays.
We are seeking a motivated and enthusiastic peptide chemist/chemical biologist. This project will be multidisciplinary, involving synthetic and peptide chemistry, biophysical characterisation of peptide hits, and molecular and cell biology. We are therefore seeking someone with experience in a selection of these techniques and a willingness to learn others as dictated by the project. Experience with the development, optimisation and testing of peptide inhibitors is essential. Experience of mRNA-display or similar display techniques would be desirable.
Opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity. Sector-leading salary and remuneration package. Access to a range of workplace benefits including a flexible working policy from day 1, generous family leave packages, interest-free season ticket loan schemes for travel and a cycle-to-work scheme. Be part of a diverse, inclusive, and collaborative work culture with various resources designed to support your personal and professional development.
Research Associate in Peptide Discovery and Development in London employer: Imperial College London
Contact Detail:
Imperial College London Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Research Associate in Peptide Discovery and Development in London
✨Tip Number 1
Network like a pro! Reach out to current or former employees at Imperial College London or the LSCCB. A friendly chat can give us insider info on the team and the work culture, plus it might just get your name on the radar.
✨Tip Number 2
Show off your skills in interviews! Prepare to discuss your experience with peptide chemistry and mRNA display techniques. We want to see your passion and how you can contribute to our vibrant research group.
✨Tip Number 3
Don’t forget to ask questions during your interview! Inquire about the collaborative aspects of the role and how you can grow within the team. This shows us that you’re genuinely interested in the position and the research.
✨Tip Number 4
Apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, we love seeing candidates who take the initiative to connect directly with us.
We think you need these skills to ace Research Associate in Peptide Discovery and Development in London
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in peptide chemistry and chemical biology. We want to see how your skills align with the role, so don’t be shy about showcasing your past projects and achievements!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you’re excited about this position and how your background makes you a perfect fit for our team. Keep it engaging and personal – we love to see your enthusiasm!
Showcase Your Skills: In your application, be sure to mention any specific techniques you’ve worked with, especially those related to mRNA display or peptide inhibitors. We’re looking for someone who’s not just experienced but also eager to learn and adapt!
Apply Through Our Website: We encourage you to apply directly through our website. It’s the best way to ensure your application gets into the right hands. Plus, it shows us you’re serious about joining our vibrant research group!
How to prepare for a job interview at Imperial College London
✨Know Your Peptides
Make sure you brush up on your knowledge of cyclic peptides and their therapeutic applications. Be ready to discuss specific examples of peptide inhibitors you've worked on, as well as any experience with mRNA display techniques. This will show your passion and expertise in the field.
✨Showcase Your Interdisciplinary Skills
Since this role involves a mix of synthetic chemistry, cell biology, and biophysical characterisation, be prepared to highlight your experience across these areas. Share examples of how you've successfully collaborated with different teams or adapted techniques from one discipline to another.
✨Prepare for Technical Questions
Expect some technical questions related to peptide chemistry and cell culture techniques. Review your past projects and be ready to explain your methodologies and results clearly. This will demonstrate your problem-solving skills and ability to think critically about your work.
✨Express Your Enthusiasm for Collaboration
This position is part of a collaborative research programme, so it's important to convey your enthusiasm for teamwork. Share experiences where you've worked effectively in a team setting, especially in multidisciplinary environments, and express your eagerness to contribute to the vibrant research group.
