At a Glance
- Tasks: Lead innovative projects in epigenomics to tackle Alzheimer's and dementia research.
- Company: Join the UK Dementia Research Institute at Imperial College London, a leader in dementia research.
- Benefits: Competitive salary, 41 days off, generous pension, and career development opportunities.
- Other info: Collaborative environment with mentoring opportunities and strong national research links.
- Why this job: Make a real impact in dementia research while working with cutting-edge technologies.
- Qualifications: Experience in epigenomics, nuclei isolation, and single-cell genomic technologies required.
The predicted salary is between 49017 - 57472 € per year.
Launched in 2017, the UK DRI stands as a beacon of scientific innovation, representing an unprecedented £300 million investment in dementia research - the largest of its kind in UK history. The purpose of the UK DRI is to transform the outlook for people living with or at risk of neurodegenerative conditions through research.
Applications are invited for a Research Associate in oligodendrocyte and neuroimmune epigenomics to join the lab of Dr Alexi Nott in the UK DRI at Imperial. Following a new collaborative UK DRI Key Questions Award with Dr Sarah Marzi (King's), Dr Rikesh Rajani (Edinburgh), and Dr Dervis Salih (UCL), we are seeking to appoint a dynamic postdoctoral researcher to lead one or more projects to characterise the epigenome of oligodendrocytes and neuroimmune cell types in early Alzheimer's and resilience to dementia using patient-derived samples. This post is funded for three years: the first 1.5 years based at Imperial on the White City Campus under the guidance of Dr Alexi Nott, where you will profile the epigenome of brain-derived oligodendrocytes and neuroimmune cell types. The second phase of the project will be in the lab of Dr Sarah Marzi, at the Denmark Hill Campus of King's College London, to examine the epigenome of macroglia at single-cell resolution. You will contribute to the design and generation of large-scale 'omics datasets with a primary focus on epigenomic analysis at cell-type-enriched and single-nuclei resolution to address major research questions relevant to Alzheimer's and resilience to dementia.
What you would be doing:
- Using your experience in (epi)genomics of the brain, you will generate cell-type-enriched and single-nuclei CUT&Tag data from patient-derived brain tissue and stem cell model systems.
- Work collaboratively as part of a multi-site, multidisciplinary research team.
What we are looking for:
We are seeking a motivated and organised researcher who is excited by the science we do! You will have:
- Experience in nuclei isolation, preferably from brain and/or human tissue.
- Experience of fluorescence-activated nuclei sorting (FANS), and/or FACS.
- Experience in epigenomics and/or single-cell genomic technologies.
What we can offer you:
This role is part of the UK Dementia Research Institute (UK DRI) at Imperial College London, located in the Department of Brain Sciences. Postdocs in the UK DRI at Imperial enjoy excellent career development opportunities with:
- Access to a range of cutting-edge technologies.
- An inclusive and collegial working environment with the opportunity to mentor, supervise and teach students.
- Strong national links through the UK DRI with attendance at its annual scientific meeting 'Connectome'.
- The opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity.
- Grow your career: gain access to Imperial's sector-leading dedicated career support for researchers as well as opportunities for promotion and progression.
- Sector-leading salary and remuneration package (including 41 days off a year and generous pension schemes).
- Be part of a diverse, inclusive and collaborative work culture with various staff networks and resources to support your personal and professional wellbeing.
This is a full-time fixed term role based at our White City Campus. If you require any further details about the role, please contact: Dr Alexi Nott and Dr Sarah Marzi.
Research Associate in Epigenomics - UK Dementia Research Institute - London employer: Imperial College London
The UK Dementia Research Institute at Imperial College London is an exceptional employer, offering a dynamic and inclusive work environment dedicated to groundbreaking research in neurodegenerative conditions. With access to cutting-edge technologies, extensive career development opportunities, and a strong focus on employee wellbeing, you will be part of a collaborative team committed to transforming the future for those affected by dementia. Enjoy a competitive salary package, generous leave, and the chance to contribute to meaningful scientific advancements in a world-leading institution.
StudySmarter Expert Advice🤫
We think this is how you could land Research Associate in Epigenomics - UK Dementia Research Institute - London
✨Tip Number 1
Network like a pro! Reach out to current or former employees at the UK Dementia Research Institute on LinkedIn. A friendly chat can give us insights into the team culture and maybe even a referral!
✨Tip Number 2
Prepare for the interview by diving deep into the latest research in epigenomics and dementia. We want to show that we’re not just passionate but also knowledgeable about the field!
✨Tip Number 3
Practice our pitch! We should be ready to explain how our experience aligns with the role. Highlight specific projects or skills that relate directly to the job description.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure our application gets seen. Plus, it shows we’re serious about joining the team at the UK DRI.
We think you need these skills to ace Research Associate in Epigenomics - UK Dementia Research Institute - London
Some tips for your application 🫡
Tailor Your CV:Make sure your CV is tailored to the role of Research Associate in Epigenomics. Highlight your experience in (epi)genomics, nuclei isolation, and any relevant technologies like FACS or FANS. We want to see how your skills match what we're looking for!
Craft a Compelling Cover Letter:Your cover letter is your chance to shine! Use it to express your passion for dementia research and how you can contribute to our mission at the UK DRI. Be genuine and let us know why you're excited about this opportunity.
Showcase Collaborative Spirit:Since this role involves working in a multidisciplinary team, make sure to mention any previous collaborative projects you've been part of. We love seeing how you work with others to achieve common goals!
Apply Through Our Website:Don't forget to apply through our website! It’s the best way to ensure your application gets to us directly. Plus, it makes the process smoother for everyone involved. We can't wait to hear from you!
How to prepare for a job interview at Imperial College London
✨Know Your Epigenomics Inside Out
Make sure you brush up on your knowledge of epigenomics, especially as it relates to neurodegenerative conditions like Alzheimer's. Be prepared to discuss your previous research experiences and how they align with the role's focus on oligodendrocytes and neuroimmune cell types.
✨Showcase Your Technical Skills
Highlight your experience with nuclei isolation, FANS, and FACS during the interview. Bring examples of past projects where you've successfully used these techniques, as this will demonstrate your hands-on expertise and readiness for the role.
✨Emphasise Collaboration
Since this position involves working in a multi-site, multidisciplinary team, be ready to talk about your collaborative experiences. Share specific examples of how you've worked with others to achieve research goals, and express your enthusiasm for contributing to a team environment.
✨Ask Insightful Questions
Prepare thoughtful questions about the research projects and the team dynamics at the UK DRI. This shows your genuine interest in the role and helps you assess if the environment is the right fit for you. Consider asking about future directions of the research or opportunities for mentorship.
