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- Tasks: Join a team tackling antimicrobial resistance through innovative research in molecular bacteriology.
- Company: World-leading institution focused on impactful scientific research.
- Benefits: Sector-leading salary, 41 days off, generous pension, and career development opportunities.
- Why this job: Contribute to groundbreaking research that addresses a major global health challenge.
- Qualifications: PhD in bacteriology or related field; experience with Gram-negative bacteria and collaborative research.
- Other info: Dynamic, inclusive environment with resources for personal and professional growth.
The predicted salary is between 37800 - 42000 £ per year.
This post is based in the laboratory of Professor Jessica Blair (University of Birmingham), with co-investigators at the Universities of Birmingham and Nottingham, Imperial, and the Quadram Institute. This multi-disciplinary project aims to understand how the host environment affects bacterial accumulation of antibiotics, via modulation of the cell envelope and efflux systems.
Antimicrobial resistance (AMR) represents a significant and growing global health threat, with an estimated 39 million deaths directly attributed to AMR between 2025–2050. Of particular concern are Gram-negative bacteria which possess two cell membranes, including a hard-to-penetrate outer membrane decorated with efficient efflux systems. These structural barriers severely limit intracellular accumulation of antibiotic drugs, rendering many ineffective. Despite a renewed focus on AMR research, there is still limited understanding of how to develop antibiotics that can cross these membranes and accumulate within bacteria.
Working with others, the appointee will contribute to this project by understanding how the membrane excludes antibiotics under diverse conditions. This will include the generation of mutant strains, lipidomics analysis, biochemical assays and measurements of membrane barrier function.
Essential criteria for the role include:
- A PhD in bacteriology or related field. Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £43,863 - £47,223 per annum.
- Experience in genetic manipulation of Gram-negative bacteria.
- Ability to work collaboratively, experience in experimental planning, troubleshooting, data analysis, and safe laboratory working practices.
- One or more of the following: Experience in studying membrane biology and/or efflux systems; Knowledge of antibiotics and resistance.
Become part of a multidisciplinary team working on one of the major challenges in antibiotic drug discovery. The opportunity to develop your research career at a world-leading institution and be part of our mission to continue science for humanity. Grow your career: gain access to Imperial’s sector-leading resources as well as opportunities for promotion and progression. Sector-leading salary and remuneration package (including 41 days off a year and generous pension schemes). Be part of a diverse, inclusive and collaborative work culture with various resources to support your personal and professional development.
Post-Doctoral Research Associate in Molecular Bacteriology in London employer: Imperial College London
Contact Detail:
Imperial College London Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Post-Doctoral Research Associate in Molecular Bacteriology in London
✨Tip Number 1
Network like a pro! Reach out to your contacts in the field of bacteriology and antimicrobial resistance. Attend conferences or seminars where you can meet potential collaborators or employers. Remember, it’s all about who you know!
✨Tip Number 2
Show off your skills! Prepare a portfolio showcasing your research projects, especially those related to genetic manipulation and membrane biology. This will help you stand out during interviews and discussions.
✨Tip Number 3
Practice makes perfect! Conduct mock interviews with friends or mentors to refine your responses. Focus on how your experience aligns with the project goals, especially regarding antibiotic resistance and efflux systems.
✨Tip Number 4
Apply through our website! We’ve got loads of opportunities waiting for you. Make sure to tailor your application to highlight your collaborative spirit and passion for tackling antimicrobial resistance.
We think you need these skills to ace Post-Doctoral Research Associate in Molecular Bacteriology in London
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the role. Highlight your PhD and any relevant experience in bacteriology, especially with Gram-negative bacteria. We want to see how your skills align with our project on antimicrobial resistance!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Explain why you're passionate about tackling antimicrobial resistance and how your background makes you a perfect fit for our multidisciplinary team. Let us know what excites you about this research!
Showcase Your Collaborative Spirit: We value teamwork here at StudySmarter. In your application, mention any past experiences where you've worked collaboratively on research projects. This will show us that you can thrive in our inclusive and diverse work culture.
Apply Through Our Website: Don't forget to apply through our website! It’s the best way to ensure your application gets to us directly. Plus, it helps us keep track of all the amazing candidates like you who are eager to join our mission in science for humanity.
How to prepare for a job interview at Imperial College London
✨Know Your Science
Make sure you brush up on the latest research in molecular bacteriology, especially around antimicrobial resistance and Gram-negative bacteria. Be prepared to discuss your PhD work and how it relates to the project, as well as any relevant techniques like genetic manipulation or lipidomics analysis.
✨Show Your Collaborative Spirit
This role is all about teamwork, so be ready to share examples of how you've successfully worked with others in the lab. Highlight your experience in experimental planning and troubleshooting, and demonstrate your ability to communicate effectively with a multidisciplinary team.
✨Prepare for Technical Questions
Expect questions that dive deep into your technical skills, particularly around membrane biology and efflux systems. Brush up on your knowledge of antibiotics and resistance mechanisms, and be ready to explain complex concepts in a clear and concise manner.
✨Ask Insightful Questions
At the end of the interview, don’t forget to ask thoughtful questions about the project and the team. This shows your genuine interest in the role and helps you gauge if the environment is the right fit for you. Consider asking about future directions of the research or how success is measured within the team.
