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- Tasks: Engineer enzymes using cutting-edge AI technology and collaborate with a multidisciplinary team.
- Company: Join Imperagen, an innovative AI-powered enzyme engineering company in Manchester.
- Benefits: Competitive salary, equity options, and the chance to work on groundbreaking projects.
- Other info: Exciting opportunity for career growth in a dynamic and collaborative environment.
- Why this job: Be part of a pioneering team shaping the future of biocatalysis and lab automation.
- Qualifications: PhD in chemistry or biochemistry, with experience in enzyme assays and analytical techniques.
The predicted salary is between 40000 - 50000 £ per year.
About Imperagen
Imperagen is building an AI-powered enzyme engineering company focused on biocatalysis. Our ambition is to create a proprietary AI platform that connects computational design, experimental validation, and real-world commercial outcomes in a system that gets smarter over time. We believe the future of biocatalysis will be shaped by autonomous closed-loop experimentation, where AI, software, and lab workflows work together to accelerate discovery, improve decision quality, and compound learning across programs.
The Role
We are hiring a biocatalysis and analytical development expert to join our team in Manchester. You will work closely within our multidisciplinary team delivering enzyme engineering programs and contributing to the development of our closed-loop enzyme technology platform.
Responsibilities
- This is a laboratory-based role, where the primary task will be to use Imperagen’s closed-loop platform to engineer enzymes in commercial programs.
- You will have responsibility for maintaining the analytical equipment (HPLC, UPLC and LC-MS).
- Knowledge of biocatalysis and enzyme chemistry is also highly desirable.
- Establish and optimise analytical and screening methods using UV/Vis, fluorescence, HPLC, and MS.
- Provide expertise in analytical methodologies and techniques to the team, especially relative to high throughput assay development and maintenance of the equipment.
- Provide expertise in biocatalysis and biotransformations reactions to the team.
- Design and perform molecular biology experiments including PCR and site-directed mutagenesis.
- Express recombinant proteins (e.g. in E. coli) and carry out purification protocols.
- Develop and run enzyme screening and characterisation assays.
- Analyse, document, and communicate experimental data.
- Collaborate with computational scientists to integrate experimental and in silico workflows.
- Contribute to development of automated and scalable laboratory systems and processes.
Required Experience and Qualifications
- PhD in chemistry, biochemistry or a related field.
- Experience with enzyme assays and analytical techniques (HPLC, UPLC, LC-MS, GC preferred).
- Deep understanding of biocatalysis and biotransformation reaction chemistry.
- Strong understanding of enzyme engineering and directed evolution.
- Experience with microbial culture and recombinant protein expression.
- Proficiency in molecular biology techniques.
- Strong teamwork and communication skills.
Preferred Experience
- Postdoctoral or industry experience in enzyme engineering.
- Knowledge of enzyme mechanisms, kinetics, or structural biology.
- Experience with lab automation or high-throughput workflows.
- Familiarity with computational biology tools or data systems.
Eligibility to work in the UK
- Candidates must have the legal right to work in the UK.
- Please note that Imperagen is not able to provide visa or work permit sponsorship for this role.
Compensation
Imperagen offers a competitive salary plus equity.
Why Join Imperagen
This is a rare opportunity to build something foundational. You will join a skilled and motivated team, working on real-world systems where software, models, and experimental science come together.
Closing date: Wednesday 13th May
Relevant candidates should reach out to us on:
Biocatalysis & Analytical Development Scientist in Warrington employer: Imperagen
Contact Detail:
Imperagen Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Biocatalysis & Analytical Development Scientist in Warrington
✨Tip Number 1
Network like a pro! Reach out to people in the biocatalysis and analytical development field on LinkedIn or at industry events. A friendly chat can lead to opportunities that aren’t even advertised yet.
✨Tip Number 2
Show off your skills! Prepare a portfolio or a presentation showcasing your past projects and achievements in enzyme engineering. This will help you stand out during interviews and discussions.
✨Tip Number 3
Practice makes perfect! Conduct mock interviews with friends or mentors to refine your responses, especially around your experience with HPLC, UPLC, and LC-MS. Confidence is key!
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets noticed. Plus, it shows you’re genuinely interested in joining our innovative team at Imperagen.
We think you need these skills to ace Biocatalysis & Analytical Development Scientist in Warrington
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the role of Biocatalysis & Analytical Development Scientist. Highlight your relevant experience with enzyme assays, analytical techniques, and any specific projects that showcase your skills in biocatalysis.
Craft a Compelling Cover Letter: Your cover letter should tell us why you're passionate about biocatalysis and how your background aligns with our mission at Imperagen. Share specific examples of your work that demonstrate your expertise and enthusiasm for the field.
Showcase Your Teamwork Skills: Since this role involves collaboration with a multidisciplinary team, emphasise your teamwork and communication skills. Mention any past experiences where you successfully worked with others to achieve a common goal.
Apply Through Our Website: We encourage you to apply through our website for a smoother application process. It’s the best way for us to receive your application and ensure it gets the attention it deserves!
How to prepare for a job interview at Imperagen
✨Know Your Biocatalysis Basics
Make sure you brush up on your biocatalysis and enzyme chemistry knowledge. Be ready to discuss specific techniques you've used, like HPLC or LC-MS, and how they relate to the role. This shows you're not just familiar with the theory but have practical experience too.
✨Showcase Your Analytical Skills
Prepare to talk about your experience with analytical methodologies. Think of examples where you've established or optimised screening methods. Highlight any high-throughput assay development you've been involved in, as this is key for the position.
✨Collaboration is Key
Imperagen values teamwork, so be ready to share examples of how you've collaborated with others, especially in multidisciplinary teams. Discuss any experiences where you worked alongside computational scientists or contributed to lab automation projects.
✨Communicate Clearly
Since you'll need to analyse and document experimental data, practice explaining complex concepts in a straightforward way. During the interview, focus on clear communication to demonstrate your ability to convey scientific information effectively.