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- Tasks: Engineer enzymes using AI-powered technology and collaborate on innovative projects.
- Company: Join Imperagen, a cutting-edge AI enzyme engineering company in Manchester.
- Benefits: Competitive salary, equity options, and a chance to work on groundbreaking science.
- Other info: Dynamic lab environment with opportunities for real-world impact and career growth.
- Why this job: Be part of a revolutionary team shaping the future of biocatalysis.
- Qualifications: PhD in chemistry or biochemistry with experience in enzyme assays and analytical techniques.
The predicted salary is between 40000 - 50000 £ per year.
About Imperagen
Imperagen is building an AI-powered enzyme engineering company focused on biocatalysis. Our ambition is to create a proprietary AI platform that connects computational design, experimental validation, and real-world commercial outcomes in a system that gets smarter over time. We believe the future of biocatalysis will be shaped by autonomous closed-loop experimentation, where AI, software, and lab workflows work together to accelerate discovery, improve decision quality, and compound learning across programs.
The Role
We are hiring a biocatalysis and analytical development expert to join our team in Manchester. You will work closely within our multidisciplinary team delivering enzyme engineering programs and contributing to the development of our closed-loop enzyme technology platform.
Responsibilities
- This is a laboratory-based role, where the primary task will be to use Imperagen’s closed-loop platform to engineer enzymes in commercial programs.
- You will have responsibility for maintaining the analytical equipment (HPLC, UPLC and LC-MS).
- Knowledge of biocatalysis and enzyme chemistry is also highly desirable.
- Establish and optimise analytical and screening methods using UV/Vis, fluorescence, HPLC, and MS.
- Provide expertise in analytical methodologies and techniques to the team, especially relative to high throughput assay development and maintenance of the equipment.
- Provide expertise in biocatalysis and biotransformations reactions to the team.
- Design and perform molecular biology experiments including PCR and site-directed mutagenesis.
- Express recombinant proteins (e.g. in E. coli) and carry out purification protocols.
- Develop and run enzyme screening and characterisation assays.
- Analyse, document, and communicate experimental data.
- Collaborate with computational scientists to integrate experimental and in silico workflows.
- Contribute to development of automated and scalable laboratory systems and processes.
Required Experience and Qualifications
- PhD in chemistry, biochemistry or a related field.
- Experience with enzyme assays and analytical techniques (HPLC, UPLC, LC-MS, GC preferred).
- Deep understanding of biocatalysis and biotransformation reaction chemistry.
- Strong understanding of enzyme engineering and directed evolution.
- Experience with microbial culture and recombinant protein expression.
- Proficiency in molecular biology techniques.
- Strong teamwork and communication skills.
Preferred Experience
- Postdoctoral or industry experience in enzyme engineering.
- Knowledge of enzyme mechanisms, kinetics, or structural biology.
- Experience with lab automation or high-throughput workflows.
- Familiarity with computational biology tools or data systems.
Eligibility to work in the UK
- Candidates must have the legal right to work in the UK.
- Please note that Imperagen is not able to provide visa or work permit sponsorship for this role.
Compensation
Imperagen offers a competitive salary plus equity.
Why Join Imperagen
This is a rare opportunity to build something foundational. You will join a skilled and motivated team, working on real-world systems where software, models, and experimental science come together.
Closing date: Wednesday 13th May
Relevant candidates should reach out to us on:
Biocatalysis & Analytical Development Scientist in Bolton employer: Imperagen
Contact Detail:
Imperagen Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Biocatalysis & Analytical Development Scientist in Bolton
✨Tip Number 1
Network like a pro! Reach out to professionals in the biocatalysis field on LinkedIn or at industry events. A friendly chat can lead to opportunities that aren’t even advertised yet.
✨Tip Number 2
Show off your skills! Prepare a portfolio or a presentation that highlights your past projects and achievements in enzyme engineering. This can really set you apart during interviews.
✨Tip Number 3
Practice makes perfect! Conduct mock interviews with friends or mentors to refine your answers and boost your confidence. Focus on how your experience aligns with the role at Imperagen.
✨Tip Number 4
Apply through our website! It’s the best way to ensure your application gets noticed. Plus, it shows you’re genuinely interested in joining our innovative team at Imperagen.
We think you need these skills to ace Biocatalysis & Analytical Development Scientist in Bolton
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the role of Biocatalysis & Analytical Development Scientist. Highlight your relevant experience with enzyme assays and analytical techniques, as well as any specific projects that showcase your skills in biocatalysis.
Craft a Compelling Cover Letter: Your cover letter should tell us why you're passionate about biocatalysis and how your background aligns with our mission at Imperagen. Share specific examples of your work that demonstrate your expertise and enthusiasm for the field.
Showcase Your Teamwork Skills: Since this role involves collaboration with a multidisciplinary team, make sure to highlight your teamwork and communication skills. Share experiences where you successfully worked with others to achieve a common goal.
Apply Through Our Website: We encourage you to apply through our website for a smoother application process. This way, we can easily track your application and ensure it gets the attention it deserves!
How to prepare for a job interview at Imperagen
✨Know Your Stuff
Make sure you brush up on your biocatalysis and enzyme chemistry knowledge. Be ready to discuss specific techniques like HPLC, UPLC, and LC-MS, as well as your experience with molecular biology experiments. The more you can demonstrate your expertise, the better!
✨Show Your Team Spirit
This role is all about collaboration, so be prepared to talk about your teamwork experiences. Share examples of how you've worked with multidisciplinary teams in the past, especially in lab settings. Highlight your communication skills and how you contribute to a positive team dynamic.
✨Prepare for Practical Questions
Expect some technical questions or even problem-solving scenarios related to enzyme engineering and analytical methods. Think through potential challenges you might face in the lab and how you would tackle them. This shows you're not just knowledgeable but also practical!
✨Connect the Dots
Imperagen is looking for someone who can integrate experimental work with computational science. Be ready to discuss how your past experiences align with this vision. Talk about any projects where you've combined lab work with data analysis or automation, showcasing your ability to bridge these areas.