Senior Scientist II - Bioinformatician,Translational Medicine - Oxford

Senior Scientist II – Bioinformatician,Translational Medicine – Oxford

Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry\’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.

Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.

At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients\’ lives, advancing medicine, and supporting one another in these pursuits.

Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.

To provide focused bioinformatics expertise across Research projects. Propose bioinformatic solutions and implement tools and workflows to enable the advancement of the Company pipeline and processes.

KEY RESPONSIBILITIES

* Possess a deep understanding of bioinformatic techniques and apply knowledge to complex problems.
* Demonstrate entrepreneurship in identifying new data sources and analytical solutions.
* Develop apps and other tools which will provide scientists with the ability to easily view and integrate data from multiple sources.
* Evaluate solutions and exercise judgement to improve data management and workflow/tool development.
* Develop understanding of the scientific context and underlying strategy across a diverse range of Research projects across autoimmune, infectious diseases and oncology. Be proactive in contributing on a scientific level.
* Demonstrate project leadership qualities through proactive team participation and collaboration with other senior representatives within Research groups.
* Maintain and increase technical knowledge in relevant fields through self-study, observation, attending relevant conferences and training courses.
* Maintain accurate records of all work by completing documentation on time, following Company procedures.
* Operate in accordance with the Company\’s Health and Safety policies.

PERSON SPECIFICATION

EXPERIENCE AND KNOWLEDGE

Essential

* Will be proficient in R/BioConductor, Linux OS and shell scripting bash. Proven programming ability
* Understanding of molecular biology, cell biology, immunology or related discipline.
* Significant experience of independent research in academic or industrial setting, or transferable skills gained from professional experience.
* Proposed and driven changes in working practices that have improved efficiency, supported teams through adoption and change.
* Presented detailed scientific findings and papers to internal and external audiences.
* Experience of building NGS pipelines.
* Contributed towards the development of database systems, using SQL or similar.

Desirable
* Familiarity with machine learning and AI applications in bioinformatics.
* Previously worked or studied in the infectious disease field.
* Demonstrated experience in bioinformatics related to TCR and/or antibody research.
* Proficiency in bioinformatics tools and databases for immune receptor analysis (e.g. IMGT, VDJtools).
* Knowledge of analysing single cell RNAseq data.
* Experience with cloud computing and HPC environments.
* Mentored and coached less experienced colleagues in scientific practices and theory.

KEY BEHAVIOURAL ATTRIBUTES – ALL STAFF

* Openness and honesty
Readily offering information pertaining to work in hand whether positive or negative.
* Taking responsibility
Being prepared to accept full responsibility for tasks entrusted to them; seeing tasks through to completion and dealing with the consequences of failure or success.
* Flexibility
Being flexible to new ideas and approaches; changes of plans, objectives and/or priorities. Handling disjointed tasks effectively.
* Team spirit
Being able to work productively with others to achieve tasks. Showing consideration for the needs and feelings of others.

EDUCATION & QUALIFICATIONS

* Normally requires a PhD in a scientific discipline and a minimum of 5-8 years related experience; may include post-doctoral experience.
* MSc degree with extensive role specific equivalent research or industrial experience.