At a Glance
- Tasks: Drive analytical strategies and develop methods for biopharmaceutical analysis.
- Company: Join Immunocore, a pioneering biotech company transforming medicine.
- Benefits: Inclusive workplace, career development, and the chance to make a real impact.
- Other info: Collaborative environment with opportunities for mentorship and growth.
- Why this job: Be part of a team creating breakthrough therapies that change lives.
- Qualifications: Experience in biopharmaceutical analysis and method development required.
The predicted salary is between 36000 - 60000 £ per year.
Senior Scientist I Analytical Development - Oxford
Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry\'s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.
Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.
At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients\' lives, advancing medicine, and supporting one another in these pursuits.
Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.
As Senior Scientist I, Analytical Development, you will help execute analytical strategies across Immunocore\'s therapeutic project portfolio, driving the development and oversight of robust impurity analytical methods and control strategies. Acting within cross-functional teams, you\'ll provide technical consultancy and guide the technical transfer and validation of assays at contract manufacturers. Your role will be instrumental in delivering high-quality data and impactful contributions to the advancement of Immunocore\'s therapeutic pipeline.
Key Responsibilities
* Contribute to analytical program strategies across our therapeutic project portfolio
* Represent analytical development within cross-functional project teams, providing strategic support and technical consultancy
* Develop and qualify analytical methods for biopharmaceutical process analysis, and process related impurity testing, including methods such as host cell protein ELISA, 2D Western blotting, host cell DNA and/or endotoxin assays as well as HPLC of residual impurities
* Contribute to development and control of critical reagents for biopharmaceutical assays
* Oversee technical transfer and validation of assays at contract manufacturers in line with ICH regulatory guidelines, and develop phase appropriate specifications
* Contribute towards relevant sections of CMC regulatory documentation, e.g., IND, IMPD, BLA, MAA and help responses to any agency questions
* Develop scientists of lower grades within the analytical development team
* Prepare reports and presentations of high quality suitable for internal and external audiences.
* Independently test and, increasingly, lead lines of investigation. Propose new experiments based on emerging data and other related information. Provide support on technical aspects to others.
* Priorities: establish priorities for own work and team-based projects; make decisions on prioritisation based on the overall goals of the team, department and project, using direct evidence and personal experience as guidance.
* Technical Knowledge: share knowledge with the wider team and, across departments representing the department both internally and externally. Increasingly provide analysis of new techniques and theories from outside the Company to advance the way the company works; sharing these with leaders across the Company.
* Laboratory records: ensure that all records and information are up to date, on time and recorded to the correct standard.
* Laboratory equipment: provide technical guidance to others within the team on how to use equipment most effectively; making recommendations regarding acquisition of new pieces of equipment.
* Adhere to safe working practices in laboratories according to Immunocore EHS policies.
Experience & knowledge
Essential
* Experience in development of methods for analysis of recombinant proteins or antibodies.
* Worked in a biopharmaceutical laboratory environment.
* Hands on expertise of SDS PAGE, Western blotting of proteins and impurity testing experience (one or more of host cell protein ELISA, host cell DNA (qPCR), endotoxin, process residuals).
* Experience with early and late stage/commercial biopharmaceutical drug programs
* Presented detailed scientific findings to internal and external audiences.
* Mentored and coached less experienced colleagues in scientific practices and theory.
Desirable
* Experience with HCP coverage assessments and strategy
* Knowledge of GMP
* Experience with managing analytical activities at Contract Manufacturers.
* Led a small project team, formally or informally, through a change in practice including project management.
Education & qualifications
* Essential: BSc. Or MSc. in biochemistry, biotechnology or related discipline
* Desirable: PhD in related discipline
Senior Scientist I Analytical Development - Oxford employer: Immunocore
Immunocore is an exceptional employer that fosters a culture of innovation and collaboration, making it an ideal place for Senior Scientists to thrive. Located in Oxford, we offer competitive benefits, a commitment to employee growth through mentorship and training, and a diverse, inclusive environment where every voice is valued. Join us in our mission to develop transformative therapies that make a real difference in patients' lives while working alongside some of the brightest minds in the biotech industry.
StudySmarter Expert Advice🤫
We think this is how you could land Senior Scientist I Analytical Development - Oxford
✨Get Involved in Local Research Communities
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We think you need these skills to ace Senior Scientist I Analytical Development - Oxford
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show Immunocore that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at Immunocore.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that Immunocore does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at Immunocore
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at Immunocore. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
✨Show Your Teamwork Skills
Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into Immunocore's culture.
✨Research Recent Biotech Innovations
Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at Immunocore. This shows your passion for the industry!
