Senior Scientist I - Characterisation | CMC - Oxford in Northumberland

Senior Scientist I - Characterisation | CMC - Oxford in Northumberland

Northumberland Full-Time 50000 - 65000 £ / year (est.) No working from home possible
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At a Glance

  • Tasks: Characterise biotherapeutic molecules using advanced protein analysis and mass spectrometry techniques.
  • Company: Join Immunocore, a pioneering biotech company transforming patient care in oncology and autoimmune diseases.
  • Benefits: Inclusive workplace, competitive salary, and opportunities for professional growth.
  • Other info: Collaborative environment with mentorship opportunities and a commitment to diversity.
  • Why this job: Make a real impact on patients' lives through innovative biopharmaceutical research.
  • Qualifications: Experience in protein characterisation and strong analytical skills required.

The predicted salary is between 50000 - 65000 £ per year.

Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D embody our shared identity and drive our mission. We are dedicated to developing breakthrough therapies that transform patients' lives, advancing medicine, and supporting one another in these pursuits. Immunocore is proud to be an equal opportunity employer, committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.

To characterise the company's biotherapeutic recombinant T-cell receptor based and related molecules using a wide variety of protein characterisation and mass spectrometry methods. To contribute to the development of characterisation methods for the company's biopharmaceutical products, including peptide mapping (LC-MS/MS) and intact mass spectrometry analysis.

KEY RESPONSIBILITIES

  • Supporting drug substance and drug product impurity characterisation and identification.
  • Performing protein sequence and post translational modification identification, including glycosylation analysis.
  • Supporting drug substance and drug product process development by performing characterisation of process intermediates.
  • Contribute to the development of characterisation methods of ImmTAX and other products, including peptide mapping (LC-MS/MS) and intact mass analysis.
  • Designing and carrying out biochemical characterisation, chemical stability and comparability studies of biologics/drug products.
  • Contribute to writing study protocols and reports.
  • Independently testing and, increasingly, leading lines of investigation. Proposing new experiments based on emerging data and other related information. Providing support on technical aspects to others.
  • Establishing priorities for own work and team-based projects; making decisions on prioritisation based on the overall goals of the team, department and project, using direct evidence and personal experience as guidance.
  • Sharing knowledge with the wider team and across departments representing the department. May also act as a mentor to other colleagues, sharing scientific knowledge. Providing analysis of new techniques and theories from outside the company to advance the way the company works; sharing these with leaders across the department.
  • Ensuring that all records and information are up to date, on time and recorded to the correct standard. Supporting and encouraging others to achieve this.
  • Providing technical guidance to others within the team on how to use equipment most effectively.
  • Communicating and presenting research findings at meetings with colleagues, senior management and partners.
  • Adhere to safe working practices in laboratories according to Immunocore EHS policies.

Senior Scientist I - Characterisation | CMC - Oxford in Northumberland employer: Immunocore

Immunocore is an exceptional employer located in the vibrant city of Oxford, offering a dynamic work culture that fosters innovation and collaboration among top-tier scientists. Employees benefit from comprehensive professional development opportunities, competitive compensation, and a commitment to advancing cutting-edge research in immunology, making it an ideal place for those seeking meaningful contributions to healthcare advancements.

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Contact Details:

Immunocore Recruitment Team

StudySmarter Expert Advice🤫

We think this is how you could land Senior Scientist I - Characterisation | CMC - Oxford in Northumberland

Tip Number 1

Network like a pro! Reach out to people in your field, especially those at Immunocore. A friendly chat can open doors that a CV just can't.

Tip Number 2

Prepare for interviews by practising common questions and showcasing your expertise in protein characterisation. We want to see your passion for advancing medicine!

Tip Number 3

Show off your problem-solving skills! Be ready to discuss how you've tackled challenges in previous roles, especially in drug substance characterisation.

Tip Number 4

Don't forget to apply through our website! It’s the best way to ensure your application gets noticed and shows you're serious about joining our team.

We think you need these skills to ace Senior Scientist I - Characterisation | CMC - Oxford in Northumberland

Protein Characterisation
Mass Spectrometry
Peptide Mapping (LC-MS/MS)
Intact Mass Analysis
Biochemical Characterisation
Chemical Stability Studies
Comparability Studies

Some tips for your application 🫡

Tailor Your CV:Make sure your CV is tailored to the Senior Scientist I role. Highlight relevant experience in protein characterisation and mass spectrometry methods, as well as any specific projects that align with our mission at Immunocore.

Craft a Compelling Cover Letter:Your cover letter should tell us why you're passionate about biotherapeutics and how your skills can contribute to our goals. Be sure to mention any experience you have with peptide mapping or drug product development.

Showcase Your Team Spirit:We value collaboration, so don’t forget to mention your experience working in teams. Share examples of how you've supported colleagues or led projects, as this aligns with our inclusive workplace culture.

Apply Through Our Website:For the best chance of success, apply directly through our website. This ensures your application gets to the right people and shows us you're serious about joining our team at Immunocore!

How to prepare for a job interview at Immunocore

Know Your Science

Make sure you brush up on the latest techniques in protein characterisation and mass spectrometry. Be ready to discuss your experience with peptide mapping and intact mass analysis, as these are key responsibilities for the role.

Showcase Your Problem-Solving Skills

Prepare examples of how you've independently tested and led investigations in previous roles. Highlight any new experiments you proposed based on emerging data, as this shows initiative and critical thinking.

Communicate Clearly

Practice explaining complex scientific concepts in a straightforward manner. You'll need to present findings to colleagues and senior management, so being able to communicate effectively is crucial.

Emphasise Teamwork and Mentorship

Immunocore values collaboration, so be ready to discuss how you've worked within teams and mentored others. Share specific instances where you provided technical guidance or shared knowledge across departments.