Associate Scientist Analytical Development - Oxford

Associate Scientist Analytical Development – Oxford

Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry's most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.
Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.
At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients' lives, advancing medicine, and supporting one another in these pursuits.
Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.
As Associate Scientist Analytical Development, you will contribute to developing analytical methods to support Immunocore's expanding pipeline of biopharmaceuticals. The core focus will be development and transfer of chromatography and electrophoresis-based methods for lot release and stability testing of protein products. Working closely with experienced scientists and cross-functional teams, you'll contribute to study reports and operating procedures, drive continuous improvement, and expand your technical expertise in a dynamic, collaborative environment.
KEY RESPONSIBILITIES
* Running pre-established experimental investigations, with guidance from line managers, a mentor or colleagues.
* Developing and qualifying (ultra) high performance liquid chromatography (UHPLC), gel / capillary electrophoresis that support stability, lot release and characterisation testing as part of biopharmaceutical product development.
* Supporting process development by testing process intermediates and performing investigations.
* Contributing to the writing of operating procedures and study reports.
* Priorities: working to agreed experimental priorities and deadlines; raising issues or concerns with managers or colleagues so that these can be addressed.
* Technical knowledge: actively developing own knowledge, drawing on the experience of others and self-learning.
* Laboratory records: Ensuring that all records and data are up to date, on time and recorded to the correct standard, checking with a mentor or colleagues if unsure.
* Laboratory equipment: attending training on the use of technical instruments, using equipment appropriately, correctly and tidily.
* Health & Safety: compliance with all H&S requirements, attending appropriate training programmes
PERSON SPECIFICATION
Experience & knowledge
Essential
* A background in recombinant protein or antibody/biopharmaceutical analytical development or QC, with one or more years' experience gained in industry.
* Hands on expertise of HPLC/UHPLC (e.g. size exclusion, ion exchange, reverse phase, hydrophobic interaction) for analysis of proteins.
* Hands on expertise of electrophoretic (e.g. CE-SDS) methods for analysis of proteins.
* Recorded results and information in a concise, accurate and timely way
* Learned about new practices through observation, self-learning and an enquiring mind
* Worked and contributed actively in a diverse team environment.
Desirable
* Experience of imaging capillary IEF (icIEF), Western blotting
* Knowledge of GMP
* Experience of lab organisation/maintenance
* Proactive in ensuring high quality of their work and seeking additional responsibilities to help meeting the goals of the team
* Familiar with principles of assay qualification/ validation i.e. robustness and suitability
Education & qualifications
* BSc. Or MSc. in biochemistry, biotechnology or related discipline