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- Tasks: Conduct experiments in protein purification and downstream process development.
- Company: Immunocore is a pioneering biotech company focused on transformative medicines for unmet patient needs.
- Benefits: Enjoy a collaborative environment, opportunities for learning, and a commitment to diversity and inclusion.
- Why this job: Join a team that values innovation and aims to make a real impact in healthcare.
- Qualifications: GCSEs in maths, English, and science; BSc or MSc in relevant fields preferred.
- Other info: Entry-level position with full-time hours in Oxford, UK.
The predicted salary is between 28800 - 43200 £ per year.
Associate Process Development Scientist, Downstream
Join to apply for the Associate Process Development Scientist, Downstream role at Immunocore
Associate Process Development Scientist, Downstream
Join to apply for the Associate Process Development Scientist, Downstream role at Immunocore
Location of role Oxford, UK
Department CMC
Key Responsibilities To conduct experimental investigations to drive the downstream process development of emerging drug candidates, supportive reagents and successful establishment of production processes for manufacturing and clinical development. Protein purification is core to this role, requiring an understanding of protein characteristics to utilise column chromatography and separation techniques along with analytical assessments of purity, using methods such as SDS-PAGE and HPLC. The job requires a strong team player capable of following instructions with a drive for learning and developing knowledge and experience in downstream process development. Robust record-keeping and regular reporting of results are essential.
Key Responsibilities – All Scientists
- Conducting experiments, observing, interpreting, and responding to results.
- Following experimental protocols and writing reports
- Maintaining and increasing technical knowledge in relevant fields through self-study, observation and attending relevant conferences or training courses.
- Maintaining accurate records of all work by completing laboratory notebook on time, following company procedures.
- Ensuring laboratory equipment is operated in accordance with safety and risk guidelines, acting promptly to report any faults or problems.
- Operating in accordance with the Company’s Health and Safety policies, especially within a laboratory environment.
Specific Responsibilities
- Experiments: running pre-established experimental investigations, with guidance from line managers, a mentor or colleagues. Reviewing data with line manager or colleagues before next steps.
- Priorities: working to agreed experimental priorities and deadlines; raising issues or concerns with managers or colleagues so that these can be addressed
- Technical knowledge: actively developing own knowledge, drawing on the experience of others and self-learning
- Laboratory records: ensuring that all records and information are up to date, on time and recorded to the correct standard, checking with a mentor or colleagues if unsure
- Laboratory equipment: attending training on the use of technical instruments, using equipment appropriately, correctly and tidily; owning and maintaining assigned items of equipment
- Reporting: communicating and presenting research findings at meetings with colleagues and line manager. Regular reporting on progress of work verbally and in writing. Protocols and reports to be written and reviewed to meet the Immunocore Quality system.
- Health & Safety: compliance with all H&S requirements, attending appropriate training programmes
Essential
EXPERIENCE AND KNOWLEDGE
- Operated in a bench-based microbial or mammalian expression, biochemistry, molecular biology, analytical or bio-pharmaceutical laboratory environment with experience or familiarity in these areas:
- Protein purification
- Routine microbial culture operations
- Aseptic techniques
- Basic protein biochemistry and/or molecular biology
- Competent in the safe use of general laboratory equipment
- Recorded results and information in a concise, accurate and timely way, and in compliance with agreed standards
- Learnt about new practices through observation, self-learning and an enquiring mind
- Worked and contributed actively in a diverse team environment
Desirable
- AKTA purifications and method design
- Molecular biology skills
- Biophysical characterisation of proteins
- Mammalian expression
- An awareness of cGMP and biopharmaceutical manufacturing requirements
- DoE experience
- Able to interpret results with minimum guidance
- Proficient in general laboratory analysis software
- Implemented or influenced best lab practice
- Worked in an industrial/biotechnology laboratory environment
Education & Qualifications
- Essential: GCSE in mathematics, English and science
- Desirable: BSc. or MSc. In protein engineering, microbiology, biochemistry, molecular biology or related discipline
About the Company Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.
Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.
At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients’ lives, advancing medicine, and supporting one another in these pursuits.
Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.
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Science, Supply Chain, and Manufacturing
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Associate Process Development Scientist, Downstream employer: Immunocore
Contact Detail:
Immunocore Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Associate Process Development Scientist, Downstream
✨Tip Number 1
Familiarise yourself with the specific techniques mentioned in the job description, such as column chromatography and SDS-PAGE. Being able to discuss these methods confidently during an interview will show your understanding and readiness for the role.
✨Tip Number 2
Network with professionals in the biopharmaceutical field, especially those who have experience in downstream process development. Attend relevant conferences or workshops to make connections and gain insights that could be beneficial during your application process.
✨Tip Number 3
Prepare to demonstrate your teamwork skills, as the role requires collaboration with colleagues. Think of examples from your past experiences where you successfully worked in a team, and be ready to share these during your interview.
✨Tip Number 4
Stay updated on the latest trends and advancements in protein purification and biopharmaceutical manufacturing. This knowledge can help you engage in meaningful discussions during interviews and show your commitment to continuous learning.
We think you need these skills to ace Associate Process Development Scientist, Downstream
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in protein purification, molecular biology, and laboratory techniques. Use keywords from the job description to demonstrate that you meet the essential criteria.
Craft a Strong Cover Letter: In your cover letter, express your enthusiasm for the role at Immunocore and explain how your background aligns with their mission. Mention specific experiences that showcase your skills in downstream process development and teamwork.
Highlight Relevant Skills: Clearly outline your technical skills related to protein biochemistry, chromatography, and laboratory safety protocols. Provide examples of how you've applied these skills in previous roles or academic projects.
Proofread Your Application: Before submitting, carefully proofread your application materials for any spelling or grammatical errors. A polished application reflects your attention to detail, which is crucial in a scientific role.
How to prepare for a job interview at Immunocore
✨Understand the Role
Make sure you thoroughly understand the responsibilities of an Associate Process Development Scientist, especially in protein purification and downstream process development. Familiarise yourself with techniques like column chromatography and analytical methods such as SDS-PAGE and HPLC.
✨Showcase Teamwork Skills
Emphasise your ability to work collaboratively in a team environment. Be prepared to discuss past experiences where you contributed to a team project, highlighting your communication skills and how you supported your colleagues.
✨Demonstrate Continuous Learning
Highlight your commitment to self-improvement and staying updated with industry trends. Mention any relevant courses, conferences, or self-study you've undertaken that relate to biochemistry, molecular biology, or protein engineering.
✨Prepare for Technical Questions
Expect technical questions related to protein purification and laboratory techniques. Brush up on your knowledge of microbial culture operations, aseptic techniques, and general laboratory practices to confidently answer these queries.
