Senior Systems Integration Engineer in Cambridge

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realise health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world-changing projects, you will do more and become more than you ever thought possible.

As a Senior Systems Integration Engineer at Illumina, you will work in a dynamic, team-oriented environment to integrate, test and troubleshoot complex prototype DNA sequencing systems, with a strong focus on electrical and electronic subsystems. You will play a hands-on role in the development of early-stage and next-generation instruments, working at system level across electronics, embedded systems, hardware, firmware, software, fluidics and chemistry. A key part of the role is diagnosing complex system interactions, executing structured experiments, and driving issues to root cause in collaboration with cross-functional teams. This role is ideal for an electrical or electronics engineer who enjoys working with prototype hardware, system-level problem solving, and applying their skills to cutting-edge life-science instrumentation.

Why Illumina? Illumina offers an industry-leading remuneration package, purpose-built state-of-the-art facilities, and a collaborative, fast-moving work environment. Our employee benefits include flexible time off, private medical insurance, compassion and care time off, leisure travel insurance, pension, employee stock purchasing programme, volunteer time off, and much more. At Illumina, we push boundaries, think beyond the conventional, and work together to improve human health through genomics.

Key Responsibilities

• Hands-on integration, testing and troubleshooting of DNA sequencing systems, with particular focus on electrical and electronic subsystems
• Debugging and fault isolation of prototype hardware and embedded systems at system level
• System-level troubleshooting across electronics, firmware, software, fluidics, mechanics and chemistry
• Design, execution and documentation of system and electrical test plans
• Tracking, logging and communicating issues encountered during development
• Working effectively within cross-functional project teams (R&D, manufacturing, service, quality, marketing)
• Writing and maintaining test procedures and quality control documentation
• Supporting manufacturing by troubleshooting hardware and system-level integration issues
• Presenting technical findings and recommendations to engineering and scientific stakeholders

Required Background, Skills And Experience

• Degree in Electronic Engineering, Electrical Engineering, Embedded Systems Engineering, Mechatronics, Robotics, or a closely related discipline
• Strong hands-on experience with electronic systems, embedded hardware, or prototype instrumentation
• Proven system-level troubleshooting skills on complex electromechanical systems
• Experience working on prototypes or early-stage development hardware
• Comfortable working in a Linux environment for system operation and troubleshooting
• Meticulous, detail-oriented approach with strong analytical and problem-solving skills
• Effective interpersonal and communication skills; comfortable engaging in technical discussions across disciplines
• Ability to clearly document work and present findings to stakeholders

Desirable (nice-to-have) Experience

• Experience with fluidics, mechatronics, robotics or vision systems
• Exposure to NGS sequencing or sample preparation methods
• Experience working in regulated environments (ISO 13485, ISO 9001, GxP)
• Basic coding or scripting skills (e.g. Python, MATLAB, VB)
• Experience supporting manufacturing or design-for-manufacture activities
• Previous experience in genomics or life sciences is a plus, but not required.

We are particularly interested in strong electrical or electronics engineers who are excited to apply their skills in a genomics environment. You'll join a team of bright, energetic, and dedicated engineers and scientists who are the driving force behind Illumina's innovation and impact. Every role at Illumina contributes to meaningful work that improves lives, and this position offers the opportunity to work hands-on with complex systems at the forefront of genomic technology.

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritised openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.

Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact.

The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.