Principal Scientist – Discovery & Translational Biology
Principal Scientist – Discovery & Translational Biology

Principal Scientist – Discovery & Translational Biology

Full-Time 43200 - 72000 £ / year (est.) No home office possible
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At a Glance

  • Tasks: Lead the development of innovative oncology therapeutics and manage project strategies.
  • Company: Join a cutting-edge start-up focused on improving cancer treatment outcomes.
  • Benefits: Enjoy a competitive salary and the chance to work in a dynamic, supportive environment.
  • Why this job: Make a real impact in drug development while collaborating with passionate professionals.
  • Qualifications: PhD in a relevant field with experience in oncology biologics, especially ADCs or Bispecific Antibodies.
  • Other info: Be part of a growing team in a start-up atmosphere that values innovation.

The predicted salary is between 43200 - 72000 £ per year.

A fantastic opportunity has arisen for a Principal Scientist – Discovery & Translational Biology to join a high-potential drug-development start-up focused on developing new oncology therapeutics that significantly improve overall survival for patients with high unmet needs. Our client is at the cutting edge of oncology therapeutics, leveraging proprietary algorithms to identify novel protein fingerprints from a comprehensive membrane protein database. They are establishing their own laboratory to support their ambitious growth plans and are seeking a highly motivated Principal Scientist to join their Research Group. This is an exciting opportunity for the right candidate to make a meaningful contribution across discovery and translational sciences.

KEY DUTIES AND RESPONSIBILITIES:

  • The ideal candidate will have hands-on experience in developing novel oncology therapeutics, ideally Antibody Drug Conjugates (ADCs) or Bispecific Antibodies.
  • You should be skilled at balancing laboratory work with project leadership and have a proven track record of building successful relationships with external partners.
  • Joining a small, growing team, this dynamic role offers the opportunity to influence strategy across all aspects of early drug development.
  • You will support portfolio expansion through target validation and co-expression studies, develop workflows for hit selection and lead triage, and deliver pivotal in vivo proof-of-concept data via external partners.

ROLE REQUIREMENTS:

  • Applicants should hold a PhD in a relevant field, with significant experience in developing novel oncology biologics, ideally ADCs or Bispecific Antibodies, gained mainly within a biotech or biopharma environment.
  • Strong technical expertise in primary cell tissue culture, flow cytometry, and IHC assay development and execution is required.
  • Experience working with spheroids is desirable.
  • You must be comfortable working independently and proactively in a start-up environment.

Principal Scientist – Discovery & Translational Biology employer: Hyper Recruitment Solutions LTD

As a Principal Scientist in Discovery & Translational Biology at our innovative drug-development start-up in Cambridgeshire, you will be part of a pioneering team dedicated to transforming oncology therapeutics. We offer a collaborative work culture that fosters creativity and professional growth, alongside competitive benefits and the chance to make a significant impact on patient outcomes. With our commitment to employee development and a dynamic start-up environment, this role presents a unique opportunity to shape the future of cancer treatment while advancing your career.
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Contact Detail:

Hyper Recruitment Solutions LTD Recruiting Team

StudySmarter Expert Advice 🤫

We think this is how you could land Principal Scientist – Discovery & Translational Biology

Tip Number 1

Network with professionals in the oncology and biopharma sectors. Attend industry conferences, webinars, or local meetups to connect with potential colleagues and learn about the latest trends in drug development.

Tip Number 2

Showcase your hands-on experience with Antibody Drug Conjugates (ADCs) or Bispecific Antibodies during informal discussions or networking events. This will help you stand out as a candidate who understands the specific challenges and innovations in this area.

Tip Number 3

Familiarise yourself with the proprietary algorithms and technologies used by the company. Understanding their approach to identifying novel protein fingerprints can give you an edge in conversations and interviews.

Tip Number 4

Prepare to discuss your project leadership experiences and how you've successfully built relationships with external partners. Highlighting these skills will demonstrate your ability to thrive in a start-up environment and contribute to the company's growth.

We think you need these skills to ace Principal Scientist – Discovery & Translational Biology

PhD in a relevant field
Experience in developing novel oncology therapeutics
Hands-on experience with Antibody Drug Conjugates (ADCs)
Experience with Bispecific Antibodies
Strong technical expertise in primary cell tissue culture
Proficiency in flow cytometry
Expertise in IHC assay development and execution
Familiarity with spheroid culture techniques
Project leadership skills
Ability to build successful relationships with external partners
Independent and proactive working style
Experience in a biotech or biopharma environment
Understanding of target validation and co-expression studies
Ability to deliver in vivo proof-of-concept data

Some tips for your application 🫡

Tailor Your CV: Make sure your CV highlights your relevant experience in developing oncology therapeutics, particularly focusing on Antibody Drug Conjugates (ADCs) or Bispecific Antibodies. Use specific examples to demonstrate your hands-on experience and project leadership skills.

Craft a Compelling Cover Letter: Write a cover letter that not only outlines your qualifications but also expresses your passion for oncology research. Mention how your background aligns with the company's mission to improve patient outcomes and your enthusiasm for contributing to their innovative projects.

Highlight Technical Skills: In your application, emphasise your technical expertise in primary cell tissue culture, flow cytometry, and IHC assay development. If you have experience with spheroids, make sure to include that as well, as it is desirable for this role.

Showcase Collaborative Experience: Since the role involves building relationships with external partners, include examples of past collaborations in your application. Highlight any successful projects where you worked with others to achieve common goals, demonstrating your ability to thrive in a team-oriented environment.

How to prepare for a job interview at Hyper Recruitment Solutions LTD

Showcase Your Technical Expertise

Make sure to highlight your hands-on experience with oncology therapeutics, especially Antibody Drug Conjugates (ADCs) or Bispecific Antibodies. Be prepared to discuss specific projects where you applied your technical skills in primary cell tissue culture, flow cytometry, and IHC assay development.

Demonstrate Leadership Skills

Since this role involves balancing laboratory work with project leadership, be ready to share examples of how you've successfully led projects in the past. Discuss how you built relationships with external partners and influenced strategy in previous roles.

Prepare for Start-Up Culture

Familiarise yourself with the dynamics of a start-up environment. Be ready to discuss how you can contribute to a small, growing team and adapt to the fast-paced nature of drug development. Highlight any previous experiences in similar settings.

Ask Insightful Questions

Prepare thoughtful questions about the company's research focus and future plans. This shows your genuine interest in their work and helps you assess if the company aligns with your career goals. Inquire about their proprietary algorithms and how they impact the drug development process.

Principal Scientist – Discovery & Translational Biology
Hyper Recruitment Solutions LTD
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