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- Tasks: Support groundbreaking research in skin wound healing and cellular mechanisms.
- Company: Join the University of Hull's innovative Wound Innovation Institute.
- Benefits: Competitive salary, part-time hours, and a collaborative research environment.
- Other info: Flexible part-time role with opportunities for professional growth.
- Why this job: Make a real difference in healthcare by advancing wound healing research.
- Qualifications: Experience in biological research and lab techniques is a plus.
The predicted salary is between 33002 - 38784 £ per year.
We are committed to equality, diversity and inclusion, creating a community where colleagues feel respected and valued. We aim to reflect the diversity of our students and communities, and to strengthen our university through collaboration and diverse perspectives, across all roles at the University.
The Wound Healing team is embedded within the newly established £48M Wound Innovation Institute at the University of Hull, a state-of-the-art translational research facility dedicated to accelerating discoveries in skin wound healing, chronic wounds, and age-related skin conditions toward clinical application. This research project focuses on cellular and molecular mechanisms of skin homeostasis, fibroblast function, senescence, Nrf2 signalling, extracellular matrix remodelling, and therapeutic interventions such as Nrf2 modulation and senolytics.
This post will provide essential technical support to a funded 2-year project investigating the roles of Nrf2 in driving pro-healing secretory phenotypes versus senescence in fibroblasts, using integrated in vitro, ex vivo, and in vivo models to identify pathways for enhancing wound repair while preserving long-term skin resilience during aging. The post holder will:
- Maintain and perform routine primary human skin fibroblast cultures, including treatment with Nrf2 activators or inducible constitutive Nrf2 models.
- Apply and evaluate senolytic treatments to clear senescent cells, followed by assessment of senescence markers via SA-β-gal staining, qRT-PCR, and immunofluorescence.
- Collect, prepare, and test conditioned media from treated fibroblasts on normal human epidermal keratinocytes and in ex vivo human skin wound models.
- Routine histology work including tissue processing, sectioning, and staining/immunofluorescence.
This role is working 29.2 hours per week (0.8 FTE). The salary stated above is the full time equivalent based on working 36.5 hours per week (1 FTE).
For an informal discussion about the role, please contact Paul Hiebert, Lecturer in Wound Healing - P.Hiebert@hull.ac.uk. Applications close at 00:01am of the closing date listed. We reserve the right to close this vacancy early if we receive sufficient applications. If you are interested in this role, please submit your application as early as possible.
Research Technician employer: Hull Limited.
Contact Detail:
Hull Limited. Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Research Technician
✨Tip Number 1
Network like a pro! Reach out to people in the field, attend relevant events, and connect with professionals on LinkedIn. You never know who might have the inside scoop on job openings or can put in a good word for you.
✨Tip Number 2
Prepare for interviews by researching the company and the role. Understand their projects and values, especially around diversity and inclusion. This will help you tailor your answers and show that you're genuinely interested in being part of their team.
✨Tip Number 3
Practice makes perfect! Conduct mock interviews with friends or use online resources to get comfortable with common questions. The more you practice, the more confident you'll feel when it’s your turn to shine.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen. Plus, we love seeing candidates who take the initiative to engage directly with us.
We think you need these skills to ace Research Technician
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the Research Technician role. Highlight relevant experience and skills that match the job description, especially in areas like fibroblast cultures and histology work.
Craft a Compelling Cover Letter: Your cover letter should tell us why you're passionate about wound healing research. Share specific examples of your past work that relate to the responsibilities outlined in the job description.
Showcase Your Technical Skills: Don’t forget to emphasise your technical skills! Mention any experience with techniques like qRT-PCR or immunofluorescence, as these are key to the role and will catch our eye.
Apply Early!: We recommend applying as soon as you can. The sooner we see your application, the better! Head over to our website to submit your application and make sure you don’t miss out.
How to prepare for a job interview at Hull Limited.
✨Know Your Research
Before the interview, dive deep into the specifics of the Wound Healing team and the Wound Innovation Institute. Familiarise yourself with their projects, especially those related to Nrf2 and fibroblast functions. This shows your genuine interest and helps you connect your skills to their needs.
✨Prepare for Technical Questions
Expect questions about your experience with primary human skin fibroblast cultures and histology techniques. Brush up on your knowledge of SA-β-gal staining, qRT-PCR, and immunofluorescence. Being able to discuss these methods confidently will demonstrate your technical expertise.
✨Showcase Your Problem-Solving Skills
Think of examples from your past experiences where you faced challenges in research and how you overcame them. Be ready to discuss how you would approach potential issues in the lab, particularly regarding maintaining cell cultures or evaluating treatments.
✨Ask Insightful Questions
Prepare thoughtful questions about the role and the team's future projects. Inquire about the specific goals of the current research or how they measure success in their studies. This not only shows your enthusiasm but also helps you gauge if the position is the right fit for you.