Preclinical In-Vitro Toxicology Scientist in Slough

Preclinical In-Vitro Toxicology Scientist up to c£70k Base+ Bonus + Benefits Hampshire, Full Time ABJ6761 ONSITE- 5 days PERM An exciting opportunity has arisen for an experienced In-Vitro Regulatory Toxicology Scientist to join a leading scientific research and product development organisation focused on in-vitro and pre-clinical assessment.This is an excellent opportunity for an experienced scientist to take a technically influential role within a multidisciplinary environment, contributing to advanced pre-clinical testing capabilities across in-vitro science, product development and regulatory toxicology. You will provide technical expertise and scientific direction across in-vitro Regulatory and Genetic Toxicology, supporting pre-clinical research, product development and regulatory programmes. The role will suit an experienced toxicologist with strong hands-on laboratory expertise who can work independently, lead technical activities and collaborate with internal teams and external partners. Key Responsibilities Provide technical expertise in the development and application of in-vitro Regulatory Toxicology approaches. Lead and execute in-vitro studies, delivering robust, reliable and scientifically defensible data. Develop, optimise and apply Neutral Red, Ames and in-vitro micronucleus assays. Apply complex cell culture, exposure techniques and biological testing methodologies to investigate product safety and potential human health effects. Interpret experimental findings and bridge in-vitro data with analytical, human-use and clinical information where appropriate. Provide technical direction for new testing capabilities, methodologies and assessment strategies. Plan and deliver technical work programmes to agreed timescales, quality standards and objectives. Collaborate with multidisciplinary teams across Preclinical Science, Analytical Science, Toxicology, Clinical and Product Development. Build relationships with external technical partners, CROs, academic groups and specialist consultants. Support method transfer, validation and implementation of new technologies. Ensure data is generated and managed in line with appropriate quality and regulatory requirements within controlled, quality-assured laboratory environments. Contribute to continuous improvement of laboratory methods, processes and scientific capabilities. Prepare, author and peer-review scientific reports, technical documentation, regulatory materials, presentations and publications. Support external scientific collaborations, including method transfer and inter-laboratory validation. Experience & Skills Required Degree, MSc or PhD in Biological Sciences, Toxicology, Pharmacology, Biomedical Sciences, Cell Biology, Molecular Biology or a related discipline. Significant practical experience in in-vitro Regulatory Toxicology, Genetic Toxicology or pre-clinical area. Hands-on experience with Neutral Red, Ames and/or in-vitro micronucleus testing. Strong experience in complex cell culture, exposure techniques, biological assays and data interpretation. Experience developing, optimising, transferring or validating in-vitro testing methodologies. Understanding of relevant regulatory toxicology guidelines, including OECD, ECVAM and ICCVAM. Experience within a controlled, quality-assured laboratory environment, ideally with GMP, GLP or GxP. Ability to assess complex biological datasets using appropriate data analysis, computational or bioinformatics. Experience contributing to regulatory submissions, scientific reports, technical documentation or external scientific communications. Desirable Experience in disease modelling, molecular toxicology or adverse outcome pathway frameworks. Knowledge of bioinformatics, computational biology or advanced biological data analysis. Experience with high-content screening, high-throughput assays or innovative in-vitro platforms. Experience managing CROs, suppliers or scientific collaborations. Benefits
: Up to £70k Base+ up to 30% bonus + 20% pension To Apply: Please contact Alison Basson on 0203 909 3782 / 07814 547 440 or apply quoting ABJ6761 to
TPBN1_UKTJ