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- Tasks: Join our team to drive innovative drug discovery using plant biosynthetic tools.
- Company: HotHouse Therapeutics is pioneering natural product drug discovery with a focus on bioactive chemicals.
- Benefits: Collaborate with a dynamic team and work in an emerging field of science.
- Why this job: Be at the forefront of revolutionizing medicine while working in a multidisciplinary environment.
- Qualifications: PhD in Biology or Biochemistry, or 3+ years relevant R&D experience required.
- Other info: Training available for specific techniques; strong problem-solving and communication skills are essential.
The predicted salary is between 43200 - 72000 £ per year.
About the Company
HotHouse Therapeutics is a first mover company revolutionising natural product drug discovery. We discover the biosynthetic tools which plants have evolved to synthesise bioactive chemicals and then redeploy them to synthesise new-to-nature small molecule drugs. This is an exciting opportunity to join our growing and ambitious team as a natural product biologist and work in a completely new and emerging area of science and drug discovery. The ideal candidate will have experience working at the interface of biology and chemistry in a multi-disciplinary environment. They will work with other laboratory-based scientists and informaticians, and be responsible for driving projects forward.
Responsibilities
- Plant tissue culture
- Cloning and transformation in bacterial systems
- Reconstituting and manipulating biosynthetic pathways in heterologous systems
- Extracting and analysing natural products from plant material
- Analysing LC-MS based results to validate and improve pathway efficiencies
- Collaborating with the wider scientific team to deliver projects
Essential
- PhD in Biology, Biochemistry or a related field, or 3+ years experience in a directly comparable field of R&D
- Experience in tissue culture techniques (ideally plant TC, but specific training available)
- Experience using LC-MS based systems and interpreting results
- Experience with molecular biology techniques
- Excellent presentation and communication skills
- Strong problem-solving skills
- Ability to work independently and develop ideas
- Ability to work in a multidisciplinary team
Desirable
- Use of NMR for structure and purity analysis
- Familiarity with natural product chemistry
- Experience using transient plant expression systems
- Knowledge of plant biology
Senior Research Development Scientist employer: HotHouse Therapeutics
Contact Detail:
HotHouse Therapeutics Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Research Development Scientist
✨Tip Number 1
Make sure to highlight your experience at the intersection of biology and chemistry. This role requires a strong understanding of both fields, so be prepared to discuss specific projects where you've successfully integrated these disciplines.
✨Tip Number 2
Familiarize yourself with the latest advancements in natural product drug discovery. Being knowledgeable about current trends and technologies will show your passion for the field and your commitment to contributing to our innovative team.
✨Tip Number 3
Prepare to discuss your experience with LC-MS systems in detail. Since analyzing results from these systems is crucial for this position, being able to articulate your hands-on experience and any challenges you've overcome will set you apart.
✨Tip Number 4
Emphasize your collaborative skills and experiences. This role involves working closely with a multidisciplinary team, so sharing examples of successful teamwork and communication will demonstrate that you're a great fit for our culture.
We think you need these skills to ace Senior Research Development Scientist
Some tips for your application 🫡
Understand the Company: Familiarize yourself with HotHouse Therapeutics and their innovative approach to natural product drug discovery. Highlight your understanding of their mission and how your background aligns with their goals.
Tailor Your CV: Customize your CV to emphasize relevant experience in biology, biochemistry, and R&D. Include specific examples of your work with plant tissue culture, LC-MS systems, and molecular biology techniques.
Craft a Compelling Cover Letter: Write a cover letter that showcases your passion for natural product chemistry and your ability to work in a multidisciplinary team. Mention any specific projects or experiences that demonstrate your problem-solving skills and communication abilities.
Highlight Collaborative Experience: In your application, emphasize any previous collaborative projects you've been involved in. Discuss how you contributed to team success and how you can bring that collaborative spirit to HotHouse Therapeutics.
How to prepare for a job interview at HotHouse Therapeutics
✨Showcase Your Multidisciplinary Experience
Highlight your experience at the intersection of biology and chemistry. Be prepared to discuss specific projects where you collaborated with different scientific disciplines, as this is crucial for the role.
✨Demonstrate Technical Proficiency
Be ready to talk about your hands-on experience with plant tissue culture, LC-MS systems, and molecular biology techniques. Providing examples of how you've successfully applied these skills in past projects will impress the interviewers.
✨Communicate Clearly and Effectively
Since excellent presentation and communication skills are essential, practice explaining complex scientific concepts in a clear and concise manner. This will help you convey your ideas effectively during the interview.
✨Prepare for Problem-Solving Scenarios
Expect questions that assess your problem-solving abilities. Think of specific challenges you've faced in your research and how you overcame them, as this will demonstrate your critical thinking skills and ability to work independently.
