At a Glance
- Tasks: Lead the development of innovative bispecific TCR therapeutics targeting AML and solid tumours.
- Company: Join a pioneering biotech firm focused on next-generation immunotherapies.
- Benefits: Competitive salary, career growth, and the chance to make a real impact.
- Other info: Be part of life-saving innovations and engage with global regulatory bodies.
- Why this job: Shape the future of cancer treatment and lead a passionate team in a science-first environment.
- Qualifications: PhD in relevant field and 5+ years of biotech experience required.
The predicted salary is between 72000 - 108000 £ per year.
Job Description
We are seeking a visionary and hands‑on Head of Pipeline Biology to lead the biological development of our novel bispecific TCR therapeutics targeting AML and solid tumours. This is a pivotal role in our journey to bring first‑in‑class, first‑in‑human molecules to the clinic.
You will work closely with the Chief Scientific Officer and Protein Science leadership to guide the non‑clinical cellular testing of candidate molecules, enabling the selection of a lead candidate for full preclinical development. Your work will directly inform regulatory submissions and shape our clinical strategy.
This role requires strong team leadership, scientific understanding, and expertise in immunology, cellular biology, and molecular biology including lentiviral transduction. In this role you will be accountable for :
- Determining HLA‑restriction, for the successful and appropriate in vitro characterisation of binding specificity of candidate and T cell activation and T cell mediated killing of bispecific TCR molecules to cells.
- In vivo characterization of bispecific TCR molecules would be desirable.
Key Responsibilities
Scientific Leadership & Strategy
- Lead the preclinical biology group, overseeing in vitro and in vivo testing of bispecific TCR molecules.
- Design and ...
Head of Pipeline Biology in Oxford employer: Hlx Life Sciences
Join us as the Head of Pipeline Biology and lead a dynamic team at the forefront of next-generation immunotherapies in a mission-driven, science-first environment. We offer a collaborative culture that fosters innovation and scientific excellence, alongside opportunities for professional growth and development. With a focus on impactful work, you will play a crucial role in shaping the future of TCR bispecifics and contributing to life-saving innovations.
StudySmarter Expert Advice🤫
We think this is how you could land Head of Pipeline Biology in Oxford
✨Get Involved in Local Research Communities
Tap into local biotechnology meetups and research forums. These are great places to mingle with industry professionals, share your passion, and even discover unadvertised job openings. It's all about getting your face known in the field!
✨Leverage University Alumni Networks
If you're a recent grad, don’t underestimate the power of your university’s alumni network! Reach out to alumni working in biotechnology to gather tips about job openings at companies like Hlx Life Sciences. You'd be surprised how willing people are to help out a fellow grad!
✨Show Off Your Projects
Curate a portfolio showcasing any research projects or internships you've completed in biotechnology. This tangible evidence of your skills can really impress employers when you chat with them at networking events or interviews. It's about making that killer first impression!
✨Stay Up-to-Date with Industry Trends
Biotech is a fast-paced field, so keeping yourself updated with the latest advancements is crucial. Attend industry conferences, webinars, or workshops to broaden your knowledge and meet potential employers. Plus, it’ll give you fantastic talking points for your interviews at places like Hlx Life Sciences!
We think you need these skills to ace Head of Pipeline Biology in Oxford
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show Hlx Life Sciences that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at Hlx Life Sciences.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that Hlx Life Sciences does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at Hlx Life Sciences
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at Hlx Life Sciences. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
✨Show Your Teamwork Skills
Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into Hlx Life Sciences's culture.
✨Research Recent Biotech Innovations
Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at Hlx Life Sciences. This shows your passion for the industry!
