I'm hiring a Director of Clinical Pharmacology to help power our growing discovery and development portfolio — and to build our clinical pharmacology and pharmacometric capability from the ground up.
Sitting within Drug Discovery, you'll be the core quantitative and clinical pharmacology lead across cross-functional project teams, applying MIDD approaches to translate nonclinical PK/PD into human development strategy — informing dose selection, trial design, and risk mitigation across a modality-agnostic pipeline (small molecules, biologics, novel platforms).
You'll:
- Own clinical pharmacology strategy across multiple concurrent programmes, from IND-enabling studies through Phase 1–3
- Lead modelling & simulation — PK/PD, PBPK, population PK/PD, QSP, DDI risk — to drive data-informed decisions
- Partner across Translational Safety, Pharmacology, Biomarkers, DMPK, and Regulatory to embed clinical pharmacology into every development plan
- Author regulatory submissions (IB, IND, NDA/BLA/MAA) and represent us with regulators
- Manage CRO partnerships and bring AI-enabled approaches into the workflow
Clinical Pharmacologist employer: Hlx Life Sciences
As a leading CRO, we pride ourselves on fostering a collaborative and dynamic work environment that empowers our Clinical Research Associates to thrive. With a focus on global clinical trials, we offer unique opportunities for professional growth and development, particularly for those fluent in French and English, while supporting a diverse range of therapeutic areas. Our commitment to employee well-being and flexible working arrangements ensures that you can balance your career with personal commitments, making us an excellent employer for those seeking meaningful and rewarding work in the UK.
