Senior Director-Molecule Steward Lead in Ware

Site Name: USA - Pennsylvania - King of Prussia, Belgium-Wavre, Durham Blackwell Street, GSK HQ, Upper Providence, USA - Massachusetts - Waltham, Ware

Position Summary

The Sr Director - Molecule Steward Lead will lead a group (5‑15) of Molecule Stewards who have end‑to‑end technical accountability for a portfolio of innovative programs, including Drug Substance, Drug Product, inspection, assembly, packing and related support activities. The role provides strategic technical leadership to ensure successful new product introduction, launch, and lifecycle improvements (e.g., quality, robustness and productivity). The Senior Director will drive program alignment across a portfolio of assets from Commit to Commercial Design through Product sunset, representing MSAT in product lifecycle milestones such as Product Control Strategy development, Technology Transfer, PPQ and ongoing maintenance of the Control Strategy to meet quality and business objectives. The role requires deep expertise in long‑acting injectable products and strong technical leadership to ensure the highest levels of quality and robustness.

Key Responsibilities

• Manage a group of Molecule Stewards (5‑10) accountable for end‑to‑end technical leadership of pipeline and in‑line programs; recruit and develop a world‑class team.
• Serve on the Molecule Steward leadership team to drive portfolio and organizational excellence.
• Define and own the technical strategy through a product’s lifecycle, including product transfers, R&D to GSK sites, external manufacturing sites, and site‑to‑site transfers; lead Product Technical Lifecycle Team (PTLT) and Manufacturing Robustness Review Board (MRRB) meetings.
• Develop and deliver the Technical Lifecycle Plan (TLCP) for major geographic expansion and new technologies impacting manufacturing, analysis, packing, device and specifications.
• Maintain product history and knowledge from development through the lifecycle, aligning with knowledge management standards and serving as PHF reviewer/approver if applicable.
• Provide technical leadership for multi‑site investigations, critical deviations, troubleshooting and major change programs across supply nodes.
• Stay current with scientific knowledge, regulatory policies, guidelines and industry best practices.
• Coordinate technical review of regulatory submissions and responses across MSAT, ensuring SME and site review.
• Act as MSAT single‑point decision maker for GSC strategic team and CMC team, defining and maintaining product control strategy to meet manufacturability criteria.
• Develop and manage collaborations with technical staff across Supply Chain sites, MSAT & R&D; mentor and develop talent through effective communication.
• Manage stakeholders effectively.
• Demonstrate knowledge of risk management approaches.

Basic Qualifications

• Bachelor’s degree in life sciences, pharmaceutical sciences, biochemical engineering, or a related field.
• Experience in biopharmaceutical development or a related scientific area.
• Experience supporting molecule program management across preclinical and/or clinical stages.
• Experience working within cross‑functional, matrixed development teams.
• Experience within external regulatory frameworks (e.g., FDA, EMA, MHRA, PMDA) in a pharmaceutical or biologics development environment.
• Experience supporting technology transfer activities within a product development environment.

Preferred Qualifications

• PhD or Master’s degree preferred.
• Strong communication skills in English and experience presenting technical information to diverse audiences.
• Experience using risk‑based approaches and project management tools.
• Knowledge of global regulatory pathways for clinical development.
• Comfort working in matrixed and cross‑cultural teams.

Work Location

This role is based in Upper Providence PA, Waltham MA or Durham NC and United Kingdom (GSK HQ, London or Ware) / Wavre, Belgium / Aranda, Spain / Evreux, France. It offers a hybrid working model, combining on‑site and remote work.

If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires ranges from $220,275 to $367,125. The position also offers an annual bonus and eligibility to participate in a share‑based long‑term incentive program. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

Equal Opportunity Statement

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.