VP, CMC Project Leadership, Small Molecules

Site Name: UK - Hertfordshire - Stevenage, UK - Hertfordshire - Ware, USA - Pennsylvania - King of Prussia, USA - Pennsylvania - Upper Providence

Posted Date: May 6 2026

Position Summary

The VP, CMC Project Leadership, Small Molecules, leads a team of CMC Development working with product and process development experts to ensure that the proposed product, manufacturing processes and supply chain logistics are sufficient to support clinical trials, transfer to manufacturing sites, registration and launch of the product; and the delivery of critical lifecycle programmes. Works with internal sites and CMOs to ensure that manufacturing sites and associated logistics are capable of implementing the manufacturing process and supply chain to produce quality product for clinical studies, registration activities and initial commercial supply. Leads the assessment of technical, regulatory, quality, logistical and financial risks associated with the physical product development, manufacture and supply.

Works with GSK leaders in commercial manufacturing and logistics, therapeutic areas, franchises and R CMC Matrix Leaders; Medicine Commercialisation Leaders; project managers; the commercial supply chain and logistics organisations; manufacturing sites; Therapeutic Area and Franchise groups; Local Operating Companies; and external partners. Core member of the Medicine and Vaccine Development develops and implements effective strategies to ensure cross‑portfolio problems are resolved. Serves as the portfolio interface to one or more of the following: Oncology, Specialty, ViiV, Generalised Medicines Development, and/or Franchise Heads. In this role, provide input to partners regarding cross‑portfolio delivery, strategy, and line‑specific decision‑making forums.

Each leader reporting to this role is responsible for managing a lifecycle EPE (Estimated Project Expenditure) budget – spanning approximately 5 to 10 years – of over £30M per asset. Their responsibilities also include overseeing assets with peak year sales exceeding £500M. In addition, they lead a matrix team of around 10 people, who themselves manage line teams dedicated to specific projects.

Candidate Profile

Basic Criteria

• BSc in chemistry, life sciences, or bio(chemical) engineering.
• Extensive CMC experience in the development or manufacture of small / synthetic molecules and drug products.
• Experience in CMC, supply chain, and late phase CMC/supply‑chain development and commercialization.
• Project leadership experience, specifically leadership of global multi‑disciplinary, matrix teams.
• Experience developing and bringing medicines to market, having delivered a product through the technology transfer process in some capacity.
• Experience with global pharmaceutical CMC regulatory requirements and working at a very senior level with both internal and external groups.

Preferred Criteria

• PhD or EngD.
• Additional CMC experience in the development or manufacture of biopharmaceuticals or vaccines.
• An influential and collaborative leader.
• Learning agility and desire to learn new things outside of one's comfort zone.
• Willingness to take on diverse and agnostic assignments in product development.
• A track record of developing others at director level or above.

Equal Employment Opportunity

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.