At a Glance
- Tasks: Lead innovative oncology programmes and drive scientific advancements in cancer treatment.
- Company: Join GSK, a global biopharma leader committed to transforming cancer care.
- Benefits: Enjoy competitive salary, health benefits, and a hybrid work model.
- Other info: Dynamic environment with opportunities for professional growth and innovation.
- Why this job: Make a real impact in oncology while collaborating with top experts in the field.
- Qualifications: 10+ years in oncology drug development; strong scientific and leadership skills required.
The predicted salary is between 72000 - 88000 £ per year.
For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.
Overview
Cancer is unrelenting, but so are we. At GSK, we are committed to transforming outcomes for people with cancer through innovative science, bold ambition, and strong partnerships across the healthcare ecosystem. We focus our science where it can matter most - advancing care in cancers with high unmet need, grounded in a deep understanding of disease biology and deliberate scientific choices that connect discovery to meaningful impact in the real world.
The Portfolio Integration Lead (PIL) is a senior role in Oncology Clinical Development, responsible for shaping the advancement of multiple oncology programmes from our portfolio with a focus on particular cancers. Working closely with both the VP and Clinical Development Leads (CDLs) and cross-functional teams across GSK, this role ensures scientific alignment, portfolio coherence, and development excellence across assets. This is a senior individual contributor position that operates across the full breadth of an Oncology portfolio rather than within a single programme, enabling cross-asset integration and strategic alignment across development activities.
The PIL applies a disease-level clinical and scientific lens across the portfolio, integrating disease biology, biomarker strategy, and emerging clinical approaches to define what is scientifically feasible and inform development pathways across programmes. This includes bringing clinical context to novel biomarker strategies and trial designs, particularly for early-stage and mechanistically novel assets and across programmes with similar indications.
The position is open to candidates from either a medical or non-medical background based on the expertise required to be successful operating at the intersection of oncology disease strategy, clinical development, and portfolio leadership.
In This Role You Will:
- Provide senior scientific partnership to CDLs, particularly in areas such as disease biology, biomarker strategy, and novel treatment combinations development.
- Ensure consistent cross-programme ways of working to improve development efficiency and execution.
- Drive cross-programme portfolio working groups and ensure business level alignment.
- Drive and support clinical trial innovation based on evolving oncology treatment landscape, government regulations, basic/translational science, and emerging technologies (such as AI-enabled tools).
- Strengthen the scientific and strategic positioning of a pan-asset portfolio across multiple clinical and pre-clinical assets.
- Drive initiatives that advance data and technology strategies supporting development decision-making.
- Shape engagement with external experts and governance bodies including advisory boards where relevant.
Key Responsibilities
Portfolio Strategy & Cross-Program Integration- Shape the advancement of multiple development programs within the oncology portfolio by providing scientific insights across assets, ensuring that agreed disease strategy is implemented consistently across programs.
- Prepare detailed strategic analyses and portfolio recommendations on behalf of the Disease Area Vice President, enabling effective decision-making at senior leadership and governance levels.
- Ensure alignment and coordination across Clinical Matrix Teams (CMTs) and relevant cross-functional stakeholders in Research & Development (R&D), Global Medical Affairs (GMA) and Global Product Strategy (GPS).
- Drive disease-level strategic discussions and portfolio planning, bringing a pan-asset perspective to governance discussions and portfolio prioritization.
- Serve as a subject matter expert supporting global health authority interactions, regulatory submissions and key development milestones across multiple assets.
- Serve as a scientific thought partner to CDLs across multiple asset programs, shaping key aspects of clinical development strategy for a given tumour types, including:
- disease biology and translational science
- biomarker and precision medicine approaches
- combination strategies
- emerging clinical development opportunities
- Establish and champion consistent ways of working across programs to improve efficiency and development quality.
- Drive innovation in clinical development approaches for a given disease area, including trial design, novel endpoints, and emerging technologies such as AI-enabled analytics where appropriate.
- Maintain a deep understanding of the evolving tumour disease landscape, standards of care, and emerging science.
- Shape engagement with external experts through advisory boards.
- Synthesise portfolio-level external insights to inform and strengthen development strategy across multiple programs.
- Drive initiatives that strengthen the application of data, technology, and analytics in clinical development decision-making for a given tumour type.
- Champion innovative approaches to clinical trials and portfolio insights, ensuring the tumour portfolio remains at the forefront of emerging capabilities.
- Bachelor’s / Master’s / Advanced degree in a scientific or medical discipline. Candidates may come from a medical or scientific background; oncology drug development expertise with defined experience is expected.
- 10+ years of experience in oncology drug development within pharmaceutical or biotechnology environments, including involvement across multiple programs or assets.
- Experience of clinical development processes, regulatory pathways, and oncology therapeutic landscapes.
- Experience in operating structured matrix organizations and demonstrate decision-making and stakeholder engagement at senior organizational levels.
- Experience as a Clinical Development Lead, Medical Director, Clinical Scientist Program Lead, or equivalent program leadership role in oncology.
- Expertise in biomarker development, precision medicine strategies, or combination therapy approaches.
- Experience engaging with external scientific experts, advisory groups, and Health Authorities.
- Demonstrated ability to influence senior stakeholders and shape strategic portfolio discussions.
- Familiarity with clinical trial innovation methods, including AI/ML applications, adaptive trial designs, or real-world evidence integration.
This role offers a hybrid working model, with a mix of on-site and remote work. Remote or fully home-working arrangements are not available for this role.
Skills- Clinical Data Interpretation
- Clinical Trial Designs
- Clinical Trials Monitoring
- Digital Fluency
- Drug Development
- Drug Regulatory Affairs
- Evidence Based Decision Making
- Executive Presence
- Hematology and Oncology
- Learning Agility
- Matrix Leadership
- Real World Evidence (RWE)
- Scientific Presentations
- Strategic Direction
Senior Director, Portfolio Integration Lead - Hematology in Stevenage employer: Gsk
GSK is an exceptional employer located in Greater London, offering a dynamic and inclusive work environment that fosters innovation and collaboration. As a Senior FinOps Product Manager, you will have the opportunity to drive impactful projects while benefiting from robust employee growth opportunities and a culture that values diverse perspectives. With a commitment to professional development and a focus on agile methodologies, GSK empowers its employees to thrive in their careers while contributing to meaningful advancements in cloud financial management.
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We think you need these skills to ace Senior Director, Portfolio Integration Lead - Hematology in Stevenage
Some tips for your application 🫡
Showcase Your Relevant Experience:When applying for a role in the pharmaceutical industry, it's crucial to highlight any relevant experience you have. Whether that's internships, lab work, or even related coursework, make sure to weave this into your CV and cover letter. We want to see how your background aligns with the role you're applying for at Gsk!
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✨Understand the Science
Make sure you brush up on key pharmaceutical concepts and recent developments in the industry. You might get asked some technical questions during the interview at Gsk that show your grasp of drug development processes or regulatory requirements, so be ready to discuss them clearly.
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If you have any hands-on experience or internships in a laboratory setting, be sure to highlight these in your responses. Think about the projects you worked on, the methodologies you used, and the impact you made. It's all about telling a story that connects your background to the role you're applying for.
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