At a Glance
- Tasks: Lead innovative biomarker strategies to revolutionise oncology clinical development.
- Company: Join GSK, a global biopharma leader with a mission to impact 2.5 billion lives.
- Benefits: Enjoy competitive pay, comprehensive benefits, and a thriving work environment.
- Other info: Dynamic workplace with opportunities for growth and scientific contribution.
- Why this job: Make a real difference in patients' lives through cutting-edge research and collaboration.
- Qualifications: 5+ years in oncology biomarkers, strong leadership, and team collaboration skills required.
The predicted salary is between 54000 - 90000 £ per year.
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success.
In this role, you will be responsible for the development and effective implementation of biomarker and translational medicine strategies to support the clinical development of late-stage oncology assets. As a key member of a Clinical Matrix Team (CMT), the Clinical Biomarker Director will collaborate with the Clinical Biomarker Executive Director to establish clear decision-making criteria, define patient segmentation strategies, and integrate these into clinical development plans. You will leverage cutting-edge technologies and methodologies to discover and clinically validate biomarkers, ensuring the biomarker strategy is fully aligned with the clinical plan. This integration will optimize decision-making in drug development and enable the identification of the right patient populations for our medicines.
Please note: This position requires an on-site office-based presence 2 to 3 days a week in the UK (Stevenage); or US (Upper Providence, PA; Waltham, MA).
Responsibilities
- Collaborating closely with the Clinical Biomarker Executive Director to drive the design, alignment, and execution of clinical biomarker and translational medicine strategies focused on identifying predictive biomarkers that enable clinical success.
- Validating and implementing biomarker strategies, including target engagement, pharmacodynamic, and proof-of-mechanism biomarkers, for clinical-phase programs to support patient stratification, dose selection, and enable clinical go/no-go decisions.
- Participating in tumor-specific Biomarker Matrix teams, with responsibility for executing clinical biomarker strategies for late-stage oncology programs, while working closely with internal and external stakeholders, as well as disease area strategy teams.
- Representing Translational Medicine at Clinical Development Matrix Teams (CMT) to establish biomarker-driven decision-making criteria and their seamless integration into clinical study designs, aligning with clinical study objectives.
- Identifying cutting-edge science and technological advances to incorporate into biomarker strategies for guiding indication selection, patient enrichment, and combination strategies.
- Overseeing and/or developing sample testing plans and delivering high-quality biomarker data packages to inform clinical development and regulatory strategies.
- Managing effective relationships with clinical and scientific operations, diagnostics, medical science, medical affairs, regulatory, portfolio management, and commercial functions.
- Supporting the expansion of mechanism and disease understanding to generate insights for indication expansion and scientific exchange as needed.
- Contributing to the company’s scientific credibility through publications and presentations.
Basic Qualifications
- Minimum of 5 years of experience in the pharmaceutical industry, with a solid background in oncology clinical biomarkers - expertise in late-phase oncology studies - and translational research within clinical development.
- Background as a Scientist and/or Physician.
- Proven ability to lead cross-functional teams and execute strategic biomarker plans.
- Experience conducting clinical trials and working as part of clinical study teams.
- Expertise in interpreting clinical biomarker data and evaluating innovative biomarker technologies for clinical trial applications.
- Strong interpersonal skills and ability to thrive in a team-oriented environment.
- Demonstrated ability to influence teams and key leaders, with a track record of success.
Preferred Qualifications
- Experience with high-dimensional dataset analysis.
- Expertise in identifying predictive biomarkers and/or diagnostic development.
- Excellent communication, problem-solving, and presentation skills.
Join us in shaping the future of oncology research and making a difference in the lives of patients worldwide. Apply today!
Director, Clinical Biomarkers, Oncology in Stevenage employer: Gsk
At GSK, we are dedicated to fostering a dynamic and inclusive work environment where innovation thrives and employees are empowered to make a meaningful impact on global health. Our commitment to professional development is evident through comprehensive training programmes and opportunities for career advancement, all while working alongside passionate colleagues in state-of-the-art facilities in Stevenage. Join us in our mission to transform oncology research and improve patient outcomes, as we unite science, technology, and talent to get ahead of disease together.
StudySmarter Expert Advice🤫
We think this is how you could land Director, Clinical Biomarkers, Oncology in Stevenage
✨Unlock Networking Opportunities
Dive into industry-specific events like pharmaceutical conferences and seminars, where you can meet hiring managers from companies like Gsk. These are goldmines for making connections and learning about job openings before they hit the mainstream job boards.
✨Join Relevant Professional Bodies
Get involved with organisations such as the Royal Pharmaceutical Society or your local pharmaceutical professionals' network. Being an active member can boost your credibility and may even lead to job referrals in top organisations like Gsk.
✨Leverage Internships for Full-time Roles
If you can, consider pursuing internships in the pharmaceutical industry, especially with companies like Gsk. These opportunities often pave the way for full-time positions and allow you to demonstrate your capabilities firsthand.
✨Tailor Your Approach
When you're applying for roles, don't rush it! Take the time to customise your applications for specific positions, showcasing relevant skills and experiences that align with what Gsk is looking for. A tailored application can really make you stand out!
We think you need these skills to ace Director, Clinical Biomarkers, Oncology in Stevenage
Some tips for your application 🫡
Showcase Your Relevant Experience:When applying for a role in the pharmaceutical industry, it's crucial to highlight any relevant experience you have. Whether that's internships, lab work, or even related coursework, make sure to weave this into your CV and cover letter. We want to see how your background aligns with the role you're applying for at Gsk!
Emphasise Your Understanding of Regulations:The pharmaceutical industry is heavily regulated, so it's important to indicate your familiarity with industry standards and regulations. In your cover letter, mention any training or certifications you've received that are relevant, or discuss projects where you’ve navigated compliance. This will show Gsk that you're not just a fit for the job but also a safety-conscious candidate!
Tailor Your CV to Be Result-Driven:Craft your CV to highlight quantifiable achievements, especially if you have previous roles in pharmaceuticals or related fields. Use metrics to demonstrate your impact, such as improved processing times or successful project completions while working on trials. This analytical approach will resonate well with hiring managers at Gsk!
Convey Your Passion for the Industry:In your cover letter, express why you are passionate about working in the pharmaceutical sector. Whether it’s your desire to contribute to groundbreaking drug research or improve patient outcomes, let it shine through! At Gsk, we value candidates who are truly enthusiastic about their work—you might just stand out from the crowd.
How to prepare for a job interview at Gsk
✨Understand the Science
Make sure you brush up on key pharmaceutical concepts and recent developments in the industry. You might get asked some technical questions during the interview at Gsk that show your grasp of drug development processes or regulatory requirements, so be ready to discuss them clearly.
✨Showcase Relevant Experience
If you have any hands-on experience or internships in a laboratory setting, be sure to highlight these in your responses. Think about the projects you worked on, the methodologies you used, and the impact you made. It's all about telling a story that connects your background to the role you're applying for.
✨Know Their Products
Take some time to familiarise yourself with Gsk’s product range and recent breakthroughs. Understanding their portfolio not only shows your enthusiasm for the role but also allows you to ask insightful questions that demonstrate your interest in actively contributing to their projects.
✨Be Ready for Regulatory Scenarios
In a full-time pharmaceutical role, understanding the regulatory landscape is crucial. Prepare for situational questions that may test your problem-solving skills concerning compliance and safety standards. You could be asked how you'd handle a hypothetical issue regarding a drug’s market release, so think through your approach.
