At a Glance
- Tasks: Lead innovative drug development strategies in cardiovascular and metabolic diseases.
- Company: Join GSK, a global biopharma leader dedicated to advancing health.
- Benefits: Competitive salary, career growth, and a collaborative work environment.
- Other info: Opportunity to shape the future of medicine in a dynamic team.
- Why this job: Make a real impact on patient health through cutting-edge research.
- Qualifications: PhD, MD, or PharmD with 5+ years in clinical pharmacology and drug development.
The predicted salary is between 56250 - 68750 £ per year.
Location: Stevenage (temporary, relocating to Cambridge, UK)
For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.
The Department of Clinical Pharmacology Modelling & Simulation in Respiratory and Inflammation (CPMS R&I) at GSK is recruiting for a Director–level Clinical Pharmacologist with cardiovascular and metabolic disease expertise. This role sits within the newly established Clinical Pharmacology and Quantitative Medicine (CPQM) organisation, which aims to be a centre of excellence in Model‑Informed Drug Development (MIDD) by integrating clinical pharmacology, digital medicine, translational imaging and mechanistic/systems modelling.
You will lead the end‑to‑end application of MIDD across the drug development lifecycle - from first‑in‑human studies through filing and lifecycle management - and provide clinical pharmacology strategy and evidence‑generation input. This is an opportunity to join a highly regarded, high‑impact team with a strong publication track record, reporting directly to the Respiratory, Immunology & Inflammation Research Unit (RIIRU).
Main responsibilities and accountabilities include, but are not limited to:
- Design & Execute Model Informed and Clinical Pharmacology strategies
- Develop and implement robust MIDD & ClinPharm evidence strategies to de-risk and accelerate RIIRU programs. Aim for faster development, optimal dosing and stronger regulatory positioning across respiratory, inflammation, neurodegeneration and emerging areas — and support business development opportunities.
- Ensure robust ways of working and regulatory ready evidence. Draft and review clinical pharmacology regulatory content to support timely approvals and optimal labelling.
- Maintain up to date knowledge of FDA, EMA, CDE, PMDA and ICH expectations and embed regulatory considerations and best practices into study design and MIDD strategies.
- Build cross functional partnerships. Work closely with CPQM peers (digital medicine, translational imaging, MIDD specialists, mechanistic/systems modelling) and cross functional partners (biology, data science, computational biology, clinical, etc.). Maintain strong networks and share best practices in the CPMS community of practice.
- Build strong network key functions such as AI/ML, biomarkers, biostatistics, clinical operations, data science, computational biology and RWE to embed quantitative approaches into decision making at asset level.
- External engagement & scientific leadership
- Raise GSK’s profile in MIDD, clinical pharmacology, QSP and AI/ML integration through publications, conference presentations and active participation in scientific and regulatory fora to influence method adoption and regulatory dialogue.
Why you?
Basic Qualifications:
- PhD, MD, or PharmD
- 5+ years of industry experience in clinical pharmacology, modelling/simulation and drug development to solve practical problems in pharmaceutical industry.
- Experience in pharmacometrics and its application to clinical questions in drug development.
Preferred Qualifications:
- Experience in Cardiovascular and metabolic diseases.
- Demonstrated experience of collaboration in a multi-disciplinary team, using effective communication and taking personal accountability for timely delivery of results.
- Evidenced experience making sound judgement in complex situations and adapting to changing business needs by prioritising multiple tasks.
- Experience working with senior stakeholders in a cross functional environment.
- Track record of implementation of Model-Informed Drug Discovery and Development (MIDD) approaches to accelerate patient access to novel therapies and to expand therapeutic indications of marketed drugs.
- Drive and learning agility to build knowledge on a drug-disease system, symptom progression, standard of care, and trial design.
Skills
- Drug Design
- Drug Development
- Drug Discovery Process
- Drug Discovery Research
- Medication Safety
- Molecular Modeling
- Pharmaceutical Regulatory Compliance
- Pharmaceutical Sciences
- Pharmacodynamics
- Pharmacokinetics
- Pharmacology
- Pharmacometrics
- Pharmacovigilance
- Study Design
- Target Validation
Why GSK?
Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
Director, Cardiovascular And Metabolic Diseases, Clinical Pharmacology Modelling And Simulation in Stevenage employer: GSK
GSK is an exceptional employer, offering a dynamic work culture that fosters collaboration and innovation in the heart of Stevenage. With a strong commitment to employee growth, you will have access to extensive development opportunities while working on groundbreaking medicine projects. The hybrid work model and future relocation to Cambridge provide a unique advantage, ensuring a vibrant environment for both personal and professional advancement.
StudySmarter Expert Advice🤫
We think this is how you could land Director, Cardiovascular And Metabolic Diseases, Clinical Pharmacology Modelling And Simulation in Stevenage
✨Get Familiar with Temporary Roles in Pharma
Temporary positions in the pharmaceutical industry often arise during specific periods, like product launches or seasonal hiring sprints. Keep an eye on timelines and be proactive in reaching out to companies, especially around these busy times!
✨Join Pharma Networking Events
Participate in local and virtual pharmaceutical networking events or job fairs. This is a fantastic way to get in front of hiring managers and learn more about temporary opportunities directly from those in the know.
✨Leverage Your University Career Services
If you’re a student or recent grad, tap into your university’s career services which often have specific connections to pharma companies looking to fill temporary roles. They might even have exclusive internship programmes that lead to temp jobs!
✨Be Visible Online and Offline
Utilise platforms like LinkedIn to share your interests in temporary roles and connect with industry professionals. Plus, consider writing about relevant pharmaceutical topics to showcase your knowledge and enthusiasm—this can help you stand out to hiring companies like GSK.
We think you need these skills to ace Director, Cardiovascular And Metabolic Diseases, Clinical Pharmacology Modelling And Simulation in Stevenage
Some tips for your application 🫡
Highlight Your Relevant Experience:In the pharmaceutical industry, it's crucial to showcase any relevant experience you have, whether it's internships, lab work, or coursework. Let’s emphasise your familiarity with drug development processes and any hands-on experience you've had with lab equipment or clinical trials in your CV.
Mention Certifications and Training:If you’ve got any certifications relevant to pharmaceuticals, like Good Clinical Practice (GCP) or a certification in pharmacovigilance, make sure to include them. These show your commitment to the field and can make a positive impact on your application for a temporary role at GSK.
Show Your Flexibility and Availability:Temporary positions often require immediate availability and flexibility in working hours. In your cover letter, make it clear when you can start and your ability to adapt to changing schedules, as this is key to a successful application.
Express Your Learning Goals:Since this is a temporary role, we suggest discussing what you hope to learn or gain from the experience at GSK. This not only shows your eagerness but also helps employers see you as someone who’s ready to make the most out of the opportunity.
How to prepare for a job interview at GSK
✨Know Your Regulations
In the pharmaceutical industry, it’s crucial to understand key regulations like GMP (Good Manufacturing Practices) or GCP (Good Clinical Practices). Brush up on these standards and be ready to discuss how they influence your work approach during your interview with GSK.
✨Emphasise Adaptability
Since this is a temporary role, show that you're ready to hit the ground running. Share examples from your past experiences that demonstrate your ability to adapt quickly to new environments or changes, especially in a fast-paced setting like pharmaceuticals.
✨Highlight Relevant Skills and Tools
Whether it’s laboratory techniques or software like LabWare or SAS, make sure you can confidently talk about your technical skills. If you have experience with any specific tools used in previous roles, relate that directly to how it can help GSK achieve its goals.
✨Prepare for Technical Questions
Be ready for technical questions related to drug development processes or quality assurance. We should expect scenarios where you might have to troubleshoot a problem or suggest improvements on a project—this shows your problem-solving capability in a temporary role.
