At a Glance
- Tasks: Lead innovative analytical chemistry projects and modernise mass spectrometry platforms.
- Company: Join GSK, a global biopharma leader with a mission to impact 2.5 billion lives.
- Benefits: Competitive salary, flexible working, and opportunities for professional growth.
- Other info: Collaborative environment with strong focus on scientific excellence and career advancement.
- Why this job: Make a real difference in healthcare by advancing cutting-edge drug development technologies.
- Qualifications: BSc in Chemistry or related field; hands-on mass spectrometry experience required.
The predicted salary is between 51750 - 63250 £ per year.
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives.
We are seeking a Principal Scientist to provide expert scientific and technical contribution to the modernisation and evolution of discovery Analytical Chemistry platforms supporting developing and complex therapeutic modalities. This role supports the evolution of the current analytical LCMS platform capability beyond the current small-molecule portfolio, contributing to robust, scalable, and future-proof LCMS analysis of divalent small molecules, drug conjugates including Warhead Linker Payloads for Antibody Drug Conjugates (WLPs for ADCs), peptides and oligonucleotides.
The position plays an important role in ensuring analytical platforms are positioned to meet near-term pipeline demands, while maintaining the highest standards of scientific excellence. The successful candidate will be a hands-on mass spectrometry specialist, combining deep technical expertise in LC-MS/HRMS with a good working knowledge of platform-level analytical strategy.
Key Responsibilities:
- Mass Spectrometry & Platform Technical Delivery: Serve as a hands-on expert in mass spectrometry (LC-MS, HRMS, and related techniques), delivering high-quality analytical data and method development support for small molecule and next-generation modalities, including divalent small molecules, WLPs, and oligonucleotides. Develop, optimise, and troubleshoot mass spectrometry methods to support platform capability, ensuring robust, reproducible, and high-quality data.
- Scientific & Technical Contribution: Provide expert analytical input on complex mass spectrometry challenges, supporting method development, troubleshooting, and data interpretation. Apply strong scientific judgement to ensure robustness, reproducibility, and data quality in day-to-day analytical work.
- High-Throughput & Workflow Support: Support the integration of high-throughput purification and analytical workflows, with particular focus on mass-spectrometry-based analysis, to enable efficient end-to-end support of emerging modality pipelines.
- Collaboration & Communication: Work collaboratively with colleagues in Discovery Chemistry, Modality teams, Informatics, Automation, and external collaborators to deliver analytical support aligned with business priorities.
- Quality & Continuous Improvement: Ensure mass spectrometry and analytical work meets high standards of quality, safety, and compliance, consistent with organisational and regulatory expectations.
Basic Qualifications & Skills:
- BSc or equivalent in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related discipline, with several years of postgraduate experience in analytical chemistry and strong hands-on mass spectrometry experience.
- Demonstrable expertise in mass spectrometry techniques (e.g. LC-MS, HRMS) and familiarity with associated analytical techniques relevant to modern drug modalities.
- Strong scientific judgement and hands-on problem-solving skills in the laboratory.
- Good communication skills and the ability to work effectively across multiple functions and teams.
Preferred Qualifications & Skills:
- PhD in Analytical Chemistry, Chemistry, or a related discipline, or MSc with relevant experience, with a strong mass spectrometry focus.
- Hands-on experience supporting complex or emerging modalities such as divalent molecules, peptides WLPs, and oligonucleotides.
If this role speaks to you, please apply now. In your application, use the cover letter or CV to describe how your experience meets the requirements.
Analytical Chemistry - Platform and Mass Spectrometry principal scientist in Stevenage employer: Gsk
GSK is an exceptional employer located in Greater London, offering a dynamic and inclusive work environment that fosters innovation and collaboration. As a Senior FinOps Product Manager, you will have the opportunity to drive impactful projects while benefiting from robust employee growth opportunities and a culture that values diverse perspectives. With a commitment to professional development and a focus on agile methodologies, GSK empowers its employees to thrive in their careers while contributing to meaningful advancements in cloud financial management.
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We think you need these skills to ace Analytical Chemistry - Platform and Mass Spectrometry principal scientist in Stevenage
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Show Off Your Lab Skills:When applying for a chemistry position, make sure to highlight any lab experience you've got. Mention specific techniques and instruments you've worked with, as they can set you apart from other candidates. For us, demonstrating your practical skills is as important as your theoretical knowledge!
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