Senior Scientist - Translational Science (Immunology)

Overview

We are looking for a Senior Scientist to join our Translational Unit on a permanent basis. This is an exciting opportunity allowing you to play a critical role in bridging preclinical target and asset validation and early clinical proof of concept studies, working closely with biology leads, clinical and computational scientists.

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people\’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients\’ needs and have the highest probability of success. We unite science, technology, and talent to get ahead of disease together.

Responsibilities

• Support identification and validation of clinical biomarkers and development of clinically deployable biomarker assays, including ELISA-based and flow cytometry-based readouts.
• Utilise your expertise in immunology to assist in the design, optimisation and conduct of in vitro and ex vivo translational assays using primary human cells and tissues.
• Apply expertise in several capabilities: flow cytometry, ELISA/MSD/Luminex, gene/protein expression analysis, cell and tissue imaging, next-generation sequencing, proteomics (e.g., OLink) and other omics platforms; act as a go to expert on specific technologies.
• Effectively troubleshoot assays and, when necessary, develop alternative approaches.
• Work closely with preclinical statistics and other relevant teams to ensure robust study design of experiments.
• Present findings to internal teams, stakeholders, and governance in a balanced, clear, and precise manner.
• Maintain accurate and detailed laboratory records in alignment with data integrity expectations and ensure compliance with all relevant protocols and safety guidelines.
• Ensure compliance with all applicable laws, regulations, and ethical standards in the conduct of translational research.
• Foster a culture of innovation, collaboration, and continuous learning within the translational research team and across the organisation.

Basic Qualifications

• PhD (or equivalent) in Cell Biology, Molecular Biology, Immunology or related field or MSc (or equivalent) in Cell Biology, Molecular Biology, Immunology or related field with relevant laboratory experience.
• Background and expertise in Immunology.
• Experience in flow cytometry.
• Expertise in immunoassays (ELISA, MSD or Luminex) and primary cell culture techniques.

Preferred Qualifications

• Expertise in multi-colour flow cytometry and gene expression analysis.
• Expertise in the development of ELISA-based and flow cytometry-based biomarker assays.
• Background and expertise in autoimmune and immune-mediated diseases.
• Previous experience in pharma or biotech industry; understanding of drug discovery processes including small and large molecule development.
• Experience processing human biological samples, developing B cell, T cell and myeloid cell functional readouts, flexibility to adopt new technologies.
• Ability to understand, interpret, and communicate complex scientific data; knowledge of different omics platforms.
• Strong written and verbal communication skills, with the ability to effectively present scientific findings to internal and external stakeholders in a balanced, clear, and precise manner.
• Proven ability to balance priorities across multiple objectives, meeting timelines while maintaining attention to detail and high-performance standards. Excellent record keeping and organisational skills.
• Knowledge of regulatory guidelines and compliance requirements related to translational research and clinical development.

Closing Date for Applications: 17th September 2025 EOD

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the \’cover letter\’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we are committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

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