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- Tasks: Lead a dynamic team in biomarker discovery and translational science.
- Company: GSK is a global biopharma company focused on innovative health solutions.
- Benefits: Enjoy hybrid working options, professional development, and a supportive culture.
- Why this job: Make a real impact in healthcare while collaborating with top scientists and external partners.
- Qualifications: Ph.D. in a relevant field and extensive experience in translational science required.
- Other info: Join a diverse team committed to innovation and personal growth.
The predicted salary is between 72000 - 108000 £ per year.
Senior Director Biomarker Discovery, Translational Sciences
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Senior Director Biomarker Discovery, Translational Sciences
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Join to apply for the Senior Director Biomarker Discovery, Translational Sciences role at GSK
Site Name: UK – Hertfordshire – Stevenage, USA – Pennsylvania – Upper Providence
Posted Date: Aug 8 2025
Reporting to Vice President of Translational Sciences, Respiratory, Immunology and Inflammation Translational Unit (RIITU), the Senior Director, Biomarker Discovery, Translational Sciences will be responsible for leading laboratory teams in RIITU, delivering innovation in biomarker discovery, ensuring biomarkers are developed for transition to clinical biomarker teams as well generating experimental data to support translational evidence at disease and clinical asset level. A key aspect of this role will be to further develop biomarker insights from high-dimensional omics and genetic approaches generated in the teams at GSK and bring this insight into biomarker innovation and development.
The successful candidate will work closely with the other members of the RIITU leadership team and the overarching research unit leadership teams, GSK matrix and external partners and will represent RIITU at governance level.
Key Responsibilities:
- Translational Biomarker Discovery Leadership:
- Lead, inspire, and scale a high-performing Biomarker discovery and assay team of :20 scientists across US and UK, creating a culture of scientific rigor, innovation, and continuous improvement. Mentor and empower team members to reach their full potential, fostering a collaborative environment that maximizes the team’s collective impact on GSK’s R&D objectives.
- Oversee the biomarker assay development supporting translational science and biomarker discovery, ensuring operational excellence across assay development, context-of-use validation, and sample analysis.
- Drive the alignment with the biomarker assay group in Development organization on assay platforms and quality expectations to ensure successful assay transitions from preclinical and translational science to clinical study support.
- Drive the adoption of cutting-edge technologies and methodologies in biomarker identification and measurements; implement new approaches to enhance the quality and throughput of biomarker assays through the application of insights from resources such as the Human Cell Atlas, disease tissue multi-omics data and genetic resources (external or proprietary).
- Partner with the Disease Teams, Research Technologies and the Development organisation to identify, establish disease biomarkers for decision making throughout clinical development phases and aligned with the overall research and development goals. This will include the identification, prioritisation and validation of disease relevant biomarkers, mechanistic/surrogate biomarkers, patient stratification, and differentiated response prediction through to their deployment into clinical studies.
- Collaborate closely with cross-functional teams including the Translational, Disease Teams, Human Genetics & Genomics, biology groups, biomarker platforms, Medicine Development Teams, HBSM , data-sciences, regulatory affairs, business development and commercial to ensure seamless integration of translational research and biomarker strategies across the drug development lifecycle.
- Establish and maintain strategic collaborations with academic institutions, contract research organizations (CROs), and other external partners to access cutting-edge technologies, tools, reagents, biosamples, biomarker expertise, and research capabilities.
- Foster a network of external experts and key opinion leaders to stay at the forefront of translational science and biomarker advancements across the industry.
- Contribute to evaluation and diligence of business development opportunities.
- Provide mentorship, guidance, and professional development opportunities to ensure a high-performing and motivated team.
- Manage disease and project level resources, budgets, and timelines to ensure the successful execution of projects and achievement of milestones and RIITU objectives.
Why you?
Basic Qualifications:
We are looking for professionals with these required skills to achieve our goals:
- Ph.D. in a relevant scientific discipline (e.g., Cell/Molecular Biology, Genetics, Pharmacology, Physical Chemistry or related field)
- Extensive experience in translational science and biomarker development within the pharmaceutical or biotechnology industry with broad knowledge in technologies and methods used in translational research.
- Recognised translational biomarker expert in scientific community through publications and contributions to the field.
- Track record of developing novel biomarkers working with multi-omics evidence
- Knowledge of regulatory requirements, industry standards, best practices and compliance considerations in Translational Research and biomarker development and validation.
- Broad knowledge in technologies and methods used in translational research.
- Proven track record of program decision making through implementing biomarker strategies and delivering translational science insights in support of drug progression through clinical transition milestones.
- Experience leading/managing external collaborations and evaluation of business development opportunities.
- Strong executive management skills, with the ability to prioritize and manage multiple projects to meet timelines while maintaining attention to detail and high-performance standards.
- Excellent inclusive matrix leadership skills, with the ability to create psychological safety, inspire and motivate a team towards achieving common goals.
- Ability to adapt to a fast-paced and evolving research environment, with strong problem-solving and critical-thinking skills.
Preferred Qualifications:
If you have the following characteristics, it would be a plus:
- Awareness of bioinformatic / computational methods supporting integrated analysis and interpretation of translational and biomarker-related data sets.
Work Location:
This role is based in the United Kingdom or United States and will require on-site presence with flexibility for hybrid working arrangements.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on UKRecruitment.Adjustments@gsk.com or 0808 234 4391. The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.
Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK\’s commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/
Seniority level
-
Seniority level
Not Applicable
Employment type
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Employment type
Full-time
Job function
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Job function
Research, Analyst, and Information Technology
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Industries
Pharmaceutical Manufacturing
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Senior Director Biomarker Discovery, Translational Sciences employer: Gsk
Contact Detail:
Gsk Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Director Biomarker Discovery, Translational Sciences
✨Tip Number 1
Network with professionals in the biomarker discovery and translational sciences fields. Attend relevant conferences, webinars, and workshops to meet potential colleagues and industry leaders. This can help you gain insights into the latest trends and technologies, making you a more attractive candidate.
✨Tip Number 2
Showcase your leadership skills by engaging in community or professional groups related to biomarker research. Taking on leadership roles in these settings can demonstrate your ability to inspire and manage teams, which is crucial for the Senior Director position.
✨Tip Number 3
Stay updated on the latest advancements in omics technologies and their applications in biomarker discovery. Familiarity with cutting-edge methods will not only enhance your knowledge but also show your commitment to innovation in the field.
✨Tip Number 4
Consider reaching out to current or former employees of GSK to gain insights into the company culture and expectations for the role. This can provide you with valuable information that can help you tailor your approach during interviews.
We think you need these skills to ace Senior Director Biomarker Discovery, Translational Sciences
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in biomarker discovery and translational sciences. Use specific examples that demonstrate your leadership skills and technical expertise, particularly in high-dimensional omics and genetic approaches.
Craft a Compelling Cover Letter: In your cover letter, express your passion for biomarker innovation and how your background aligns with GSK's mission. Mention specific projects or achievements that showcase your ability to lead teams and drive scientific advancements.
Highlight Collaborative Experience: Given the cross-functional nature of the role, emphasise your experience working with diverse teams. Provide examples of successful collaborations with external partners, academic institutions, or within matrix leadership structures.
Showcase Problem-Solving Skills: Include instances where you've tackled complex challenges in biomarker development. Highlight your critical-thinking abilities and how you've adapted to fast-paced research environments to achieve project goals.
How to prepare for a job interview at Gsk
✨Showcase Your Leadership Skills
As a Senior Director, you'll be expected to lead and inspire a team. Prepare examples of how you've successfully managed teams in the past, focusing on mentorship and fostering a collaborative environment.
✨Demonstrate Your Technical Expertise
Be ready to discuss your extensive experience in translational science and biomarker development. Highlight specific projects where you implemented cutting-edge technologies or methodologies that led to successful outcomes.
✨Prepare for Cross-Functional Collaboration Questions
This role requires working closely with various teams. Think of instances where you've collaborated across departments, detailing how you navigated challenges and achieved common goals.
✨Understand GSK's Vision and Values
Familiarise yourself with GSK's mission to unite science, technology, and talent. Be prepared to discuss how your personal values align with theirs and how you can contribute to their goal of getting ahead of disease together.
